Publications by authors named "Mahmut Gozelle"

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approach reveals -(5-phenoxythiophen-2-yl)-2-(arylthio)acetamides as promising selective SIRT2 inhibitors: the case of structural optimization of virtual screening-derived hits.
Mahmut Gozelle, Filiz Bakar-Ates, Alberto Massarotti, Erva Ozkan, Habibe Beyza Gunindi

J Biomol Struct Dyn· March 2025

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2-(Methyl(phenyl)amino)-N-(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition.
Selen Gozde Kaya, Gokcen Eren, Alberto Massarotti, Filiz Bakar-Ates, Erva Ozkan, Mahmut Gozelle

Drug Dev Res· June 2024

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Hit evaluation results in 5-benzyl-1,3,4-thiadiazole-2-carboxamide based SIRT2-selective inhibitor with improved affinity and selectivity.
Mahmut Gozelle, Selen Gozde Kaya, Ahmet Bugra Aksel, Erva Ozkan, Filiz Bakar-Ates

Bioorg Chem· June 2022

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Hit-to-lead optimization on aryloxybenzamide derivative virtual screening hit against SIRT.
Semih Yagci, Mahmut Gozelle, Selen Gozde Kaya, Yesim Ozkan, Ahmet Bugra Aksel

Bioorg Med Chem· January 2021

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Pharmacophore modeling and virtual screening studies to identify novel selective SIRT2 inhibitors.
Gokcen Eren, Agostino Bruno, Sezen Guntekin-Ergun, Rengul Cetin-Atalay, Fikriye Ozgencil, Mahmut Gozelle

J Mol Graph Model· June 2019

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