Publications by authors named "Alberto Napuli"

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Increasing the structural coverage of tuberculosis drug targets.
Loren Baugh, Isabelle Phan, Darren W Begley, Matthew C Clifton, Brianna Armour, Alberto J Napuli

Tuberculosis (Edinb)· March 2015

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Combining functional and structural genomics to sample the essential Burkholderia structome.
Loren Baugh, Larry A Gallagher, Rapatbhorn Patrapuvich, Matthew C Clifton, Anna S Gardberg, Alberto Napuli

PLoS One· September 2013

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Structure of the prolyl-tRNA synthetase from the eukaryotic pathogen Giardia lamblia.
Eric T Larson, Jessica E Kim, Alberto J Napuli, Christophe L M J Verlinde, Erkang Fan

Acta Crystallogr D Biol Crystallogr· September 2012

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Screening a fragment cocktail library using ultrafiltration.
Sayaka Shibata, Zhongsheng Zhang, Konstantin V Korotkov, Jaclyn Delarosa, Alberto Napuli

Anal Bioanal Chem· September 2011

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Immobilized metal-affinity chromatography protein-recovery screening is predictive of crystallographic structure success.
Ryan Choi, Angela Kelley, David Leibly, Stephen Nakazawa Hewitt, Alberto Napuli

Acta Crystallogr Sect F Struct Biol Cryst Commun· September 2011

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Expression of proteins in Escherichia coli as fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline.
Stephen N Hewitt, Ryan Choi, Angela Kelley, Gregory J Crowther, Alberto J Napuli

Acta Crystallogr Sect F Struct Biol Cryst Commun· September 2011

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High-throughput protein production and purification at the Seattle Structural Genomics Center for Infectious Disease.
Cassie M Bryan, Janhavi Bhandari, Alberto J Napuli, David J Leibly, Ryan Choi

Acta Crystallogr Sect F Struct Biol Cryst Commun· September 2011

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Structure of a Nudix hydrolase (MutT) in the Mg(2+)-bound state from Bartonella henselae, the bacterium responsible for cat scratch fever.
Garry W Buchko, Thomas E Edwards, Jan Abendroth, Tracy L Arakaki, Laura Law, Alberto J Napuli

Acta Crystallogr Sect F Struct Biol Cryst Commun· September 2011

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BrabA.11339.a: anomalous diffraction and ligand binding guide towards the elucidation of the function of a 'putative β-lactamase-like protein' from Brucella melitensis.
Jan Abendroth, Banumathi Sankaran, Thomas E Edwards, Anna S Gardberg, Shellie Dieterich, Alberto J Napuli

Acta Crystallogr Sect F Struct Biol Cryst Commun· September 2011

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Solution structure of an arsenate reductase-related protein, YffB, from Brucella melitensis, the etiological agent responsible for brucellosis.
Garry W Buchko, Stephen N Hewitt, Alberto J Napuli, Wesley C Van Voorhis, Peter J Myler

Acta Crystallogr Sect F Struct Biol Cryst Commun· September 2011

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Solution-state NMR structure and biophysical characterization of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis.
Garry W Buchko, Stephen N Hewitt, Alberto J Napuli, Wesley C Van Voorhis, Peter J Myler

Acta Crystallogr Sect F Struct Biol Cryst Commun· September 2011

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The double-length tyrosyl-tRNA synthetase from the eukaryote Leishmania major forms an intrinsically asymmetric pseudo-dimer.
Eric T Larson, Jessica E Kim, Lisa J Castaneda, Alberto J Napuli, Zhongsheng Zhang

J Mol Biol· June 2011

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Design and initial characterization of the SC-200 proteomics standard mixture.
Andrew Bauman, Roger Higdon, Sean Rapson, Brenton Loiue, Jason Hogan, Alberto Napuli

OMICS· May 2011

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Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase.
Ethan A Merritt, Tracy L Arakaki, Robert Gillespie, Alberto J Napuli, Jessica E Kim

Mol Biochem Parasitol· May 2011

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Selective inhibitors of methionyl-tRNA synthetase have potent activity against Trypanosoma brucei Infection in Mice.
Sayaka Shibata, J Robert Gillespie, Angela M Kelley, Alberto J Napuli, Zhongsheng Zhang

Antimicrob Agents Chemother· May 2011

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Structure determination of glycogen synthase kinase-3 from Leishmania major and comparative inhibitor structure-activity relationships with Trypanosoma brucei GSK-3.
Kayode K Ojo, Tracy L Arakaki, Alberto J Napuli, Krishna K Inampudi, Katelyn R Keyloun

Mol Biochem Parasitol· April 2011

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Structure of Leishmania major methionyl-tRNA synthetase in complex with intermediate products methionyladenylate and pyrophosphate.
Eric T Larson, Jessica E Kim, Frank H Zucker, Angela Kelley, Natascha Mueller, Alberto J Napuli

Biochimie· March 2011

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Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds.
Gregory J Crowther, Alberto J Napuli, James H Gilligan, Kerstin Gagaring, Rachel Borboa

Mol Biochem Parasitol· January 2011

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Nanovolume optimization of protein crystal growth using the microcapillary protein crystallization system.
Cory J Gerdts, Glenn L Stahl, Alberto Napuli, Bart Staker, Jan Abendroth

J Appl Crystallogr· October 2010

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The structure of tryptophanyl-tRNA synthetase from Giardia lamblia reveals divergence from eukaryotic homologs.
Tracy L Arakaki, Megan Carter, Alberto J Napuli, Christophe L M J Verlinde, Erkang Fan

J Struct Biol· August 2010

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Prediction of protein crystallization outcome using a hybrid method.
Frank H Zucker, Christine Stewart, Jaclyn dela Rosa, Jessica Kim, Li Zhang, Alberto J Napuli

J Struct Biol· July 2010

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Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors.
Kayode K Ojo, Eric T Larson, Katelyn R Keyloun, Lisa J Castaneda, Amy E Derocher, Alberto J Napuli

Nat Struct Mol Biol· May 2010

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The crystal structure and activity of a putative trypanosomal nucleoside phosphorylase reveal it to be a homodimeric uridine phosphorylase.
Eric T Larson, Devaraja G Mudeppa, J Robert Gillespie, Natascha Mueller, Alberto J Napuli

J Mol Biol· March 2010

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Crystal structures of trypanosomal histidyl-tRNA synthetase illuminate differences between eukaryotic and prokaryotic homologs.
Ethan A Merritt, Tracy L Arakaki, J Robert Gillespie, Eric T Larson, Angela Kelley, Alberto J Napuli

J Mol Biol· March 2010

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X-ray structure determination of the glycine cleavage system protein H of Mycobacterium tuberculosis using an inverse Compton synchrotron X-ray source.
Jan Abendroth, Michael S McCormick, Thomas E Edwards, Bart Staker, Roderick Loewen, Alberto J Napuli

J Struct Funct Genomics· March 2010

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