Publications by authors named "Aleem Syed"

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CHAMP1 Complex Promotes Heterochromatin Assembly and Reduces Replication Stress.
Feng Li, Amira Elbakry, Felix Y Zhou, Tianpeng Zhang, Ramya Ravindranathan, Aleem Syed

bioRxiv· August 2025

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Role of Artificial Intelligence in the Diagnosis of Oral Squamous Cell Carcinoma: A Systematic Review.
Tanay Chowdhury, Pratik Kasralikar, Abdul Aleem Syed, Ramakrishna Tumati, Sandipkumar Patel

Cureus· April 2025

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Natural Language Processing (NLP)- and Machine Learning (ML)-Enabled Operating Room Optimization: A Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Systematic Review Anchored in Project Planning Theory.
Balaiah Chamarthi, Omkar Reddy Polu, Sathish Krishna Anumula, Azhar Ushmani, Pratik Kasralikar, Abdul Aleem Syed

Cureus· April 2025

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CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair.
Feng Li, Tianpeng Zhang, Aleem Syed, Amira Elbakry, Noella Holmer

Nat Commun· February 2025

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Enriched G4 forming repeats in the human genome are associated with robust well-coordinated transcription and reduced cancer transcriptome variation.
Ruth B De-Paula, Albino Bacolla, Aleem Syed, John A Tainer

J Biol Chem· November 2024

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CDK5-cyclin B1 regulates mitotic fidelity.
Xiao-Feng Zheng, Aniruddha Sarkar, Humphrey Lotana, Aleem Syed, Huy Nguyen

Nature· September 2024

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NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity.
Susan Kilgas, Aleem Syed, Patrick Toolan-Kerr, Michelle L Swift, Shrabasti Roychoudhury

Nat Commun· September 2024

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ASCC1 structures and bioinformatics reveal a novel helix-clasp-helix RNA-binding motif linked to a two-histidine phosphodiesterase.
Naga Babu Chinnam, Roopa Thapar, Andrew S Arvai, Altaf H Sarker, Jennifer M Soll, Aleem Syed

J Biol Chem· June 2024

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Author Correction: Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology.
Frantisek Filandr, Vladimir Sarpe, Shaunak Raval, D Alex Crowder, Morgan F Khan, Aleem Syed

Nat Commun· April 2024

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Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology.
Frantisek Filandr, Vladimir Sarpe, Shaunak Raval, D Alex Crowder, Morgan F Khan, Aleem Syed

Nat Commun· March 2024

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Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity.
Aleem Syed, Frantisek Filandr, Jeffrey Patterson-Fortin, Albino Bacolla, Ramya Ravindranathan

Nucleic Acids Res· October 2023

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Dynamics of the DYNLL1-MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs.
Michelle L Swift, Rui Zhou, Aleem Syed, Lisa A Moreau, Bartłomiej Tomasik

Nat Struct Mol Biol· October 2023

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Dynamics of the DYNLL1/MRE11 complex regulates DNA end resection and recruitment of the Shieldin complex to DSBs.
Rui Zhou, Michelle L Swift, Aleem Syed, Kaimeng Huang, Lisa Moreau

bioRxiv· March 2023

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Combining small angle X-ray scattering (SAXS) with protein structure predictions to characterize conformations in solution.
Naga Babu Chinnam, Aleem Syed, Greg L Hura, Michal Hammel, John A Tainer

Methods Enzymol· January 2023

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Universally Accessible Structural Data on Macromolecular Conformation, Assembly, and Dynamics by Small Angle X-Ray Scattering for DNA Repair Insights.
Naga Babu Chinnam, Aleem Syed, Kathryn H Burnett, Greg L Hura, John A Tainer

Methods Mol Biol· March 2022

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Monitoring Nuclease Activity by X-Ray Scattering Interferometry Using Gold Nanoparticle-Conjugated DNA.
Daniel J Rosenberg, Aleem Syed, John A Tainer, Greg L Hura

Methods Mol Biol· March 2022

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GRB2 enforces homology-directed repair initiation by MRE11.
Zu Ye, Shengfeng Xu, Yin Shi, Albino Bacolla, Aleem Syed

Sci Adv· August 2021

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A first-in-class Polymerase Theta Inhibitor selectively targets Homologous-Recombination-Deficient Tumors.
Jia Zhou, Camille Gelot, Constantia Pantelidou, Adam Li, Hatice Yücel, Aleem Syed

Nat Cancer· June 2021

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Targeting Allostery with Avatars to Design Inhibitors Assessed by Cell Activity: Dissecting MRE11 Endo- and Exonuclease Activities.
Davide Moiani, Daryl A Ronato, Chris A Brosey, Andrew S Arvai, Aleem Syed

Methods Enzymol· March 2019

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Charge Transport Communication through DNA by Protein Fe-S Clusters: How Far Is Not Too Far?
Aleem Syed, John A Tainer

ACS Cent Sci· January 2019

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The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.
Aleem Syed, John A Tainer

Annu Rev Biochem· June 2018

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Family of BODIPY Photocages Cleaved by Single Photons of Visible/Near-Infrared Light.
Julie A Peterson, Chamari Wijesooriya, Elizabeth J Gehrmann, Kaitlyn M Mahoney, Pratik P Goswami, Aleem Syed

J Am Chem Soc· June 2018

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Lateral diffusion and signaling of receptor for advanced glycation end-products (RAGE): a receptor involved in chronic inflammation.
Aleem Syed, Qiaochu Zhu, Emily A Smith

Eur Biophys J· January 2018

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Raman Imaging in Cell Membranes, Lipid-Rich Organelles, and Lipid Bilayers.
Aleem Syed, Emily A Smith

Annu Rev Anal Chem (Palo Alto Calif)· June 2017

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The role of a conserved membrane proximal cysteine in altering αPS2CβPS integrin diffusion.
Aleem Syed, Neha Arora, Thomas A Bunch, Emily A Smith

Phys Biol· November 2016

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