Publications by authors named "John A Tainer"

Claim this Profile
A
APOL2 Stabilizes Ku80 to Confer NHEJ-Mediated Radioresistance in Gastric Cancer.
Dan Zu, Qimei Bao, Hanyi He, Yuke Zhong, Mingcong Deng, John A Tainer

Adv Sci (Weinh)· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
RNA/DNA-binding protein TDP43 regulates DNA mismatch repair genes with implications for genome stability.
Vincent E Provasek, Albino Bacolla, Suganya Rangaswamy, Manohar Kodavati, Joy Mitra, John A Tainer

Nucleic Acids Res· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Information theory optimization of signals from small-angle scattering measurements.
Robert P Rambo, John A Tainer

Biophys J· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
RNA/DNA Binding Protein TDP43 Regulates DNA Mismatch Repair Genes with Implications for Genome Stability.
Vincent E Provasek, Albino Bacolla, Suganya Rangaswamy, Manohar Kodavati, Joy Mitra, John A Tainer

bioRxiv· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Huntingtin preserves mitochondrial genome integrity in neurons, which is impaired in Huntington's disease.
Subrata Pradhan, Sagar Gaikwad, Chi-Lin Tsai, Charlene Smith, Nan Zhang, John A Tainer

bioRxiv· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
BRCA2 C-terminal clamp restructures RAD51 dimers to bind B-DNA for replication fork stability.
Michael A Longo, Syed Moiz Ahmed, Yue Chen, Chi-Lin Tsai, Sarita Namjoshi, John A Tainer

Mol Cell· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
RNA sculpting by the primordial Helix-clasp-Helix-Strand-Loop (HcH-SL) motif enforces chemical recognition enabling diverse KH domain functions.
John A Tainer, Susan E Tsutakawa

J Biol Chem· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A predictive chromatin architecture nexus regulates transcription and DNA damage repair.
Audesh Bhat, Sonali Bhan, Aindrila Kabiraj, Raj K Pandita, Keneth S Ramos, John A Tainer

J Biol Chem· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Molecular model of TFIIH recruitment to the transcription-coupled repair machinery.
Tanmoy Paul, Chunli Yan, Jina Yu, Susan E Tsutakawa, John A Tainer

Nat Commun· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism.
Chris A Brosey, Runze Shen, John A Tainer

EMBO J· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Enriched G4 forming repeats in the human genome are associated with robust well-coordinated transcription and reduced cancer transcriptome variation.
Ruth B De-Paula, Albino Bacolla, Aleem Syed, John A Tainer

J Biol Chem· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A goldilocks computational protocol for inhibitor discovery targeting DNA damage responses including replication-repair functions.
Davide Moiani, John A Tainer

Front Mol Biosci· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair.
Jina Yu, Chunli Yan, Tanmoy Paul, Lucas Brewer, Susan E Tsutakawa, John A Tainer

Nat Commun· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chemical screening by time-resolved X-ray scattering to discover allosteric probes.
Chris A Brosey, Todd M Link, Runze Shen, Davide Moiani, Kathryn Burnett, John A Tainer

Nat Chem Biol· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chromatin remodeler BRG1 recruits huntingtin to repair DNA double-strand breaks in neurons.
Subrata Pradhan, Keegan Bush, Nan Zhang, Raj K Pandita, Chi-Lin Tsai, John A Tainer

bioRxiv· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
BRCA2 C-terminal clamp restructures RAD51 dimers to bind B-DNA for replication fork stability.
Michael A Longo, Syed Moiz Ahmed, Yue Chen, Chi-Lin Tsai, Sarita Namjoshi, John A Tainer

bioRxiv· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A prismatic view of the epigenetic-metabolic regulatory axis in breast cancer therapy resistance.
Chandrima Das, Apoorva Bhattacharya, Swagata Adhikari, Atanu Mondal, Payel Mondal, John A Tainer

Oncogene· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
ASCC1 structures and bioinformatics reveal a novel helix-clasp-helix RNA-binding motif linked to a two-histidine phosphodiesterase.
Naga Babu Chinnam, Roopa Thapar, Andrew S Arvai, Altaf H Sarker, Jennifer M Soll, John A Tainer

J Biol Chem· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthetic cationic helical polypeptides for the stimulation of antitumour innate immune pathways in antigen-presenting cells.
DaeYong Lee, Kristin Huntoon, Yifan Wang, Minjeong Kang, Yifei Lu, John A Tainer

Nat Biomed Eng· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Author Correction: Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology.
Frantisek Filandr, Vladimir Sarpe, Shaunak Raval, D Alex Crowder, Morgan F Khan, John A Tainer

Nat Commun· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer.
Jie Fu, Jianhua Ling, Ching-Fei Li, Chi-Lin Tsai, Wenjuan Yin, John A Tainer

Nat Commun· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer.
Zu Ye, Shengfeng Xu, Yin Shi, Xueqian Cheng, Yuan Zhang, John A Tainer

Nat Commun· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology.
Frantisek Filandr, Vladimir Sarpe, Shaunak Raval, D Alex Crowder, Morgan F Khan, John A Tainer

Nat Commun· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The NS1 protein of influenza B virus binds 5'-triphosphorylated dsRNA to suppress RIG-I activation and the host antiviral response.
Ryan Woltz, Brandon Schweibenz, Susan E Tsutakawa, Chen Zhao, LiChung Ma, John A Tainer

bioRxiv· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dynamics of the DYNLL1-MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs.
Michelle L Swift, Rui Zhou, Aleem Syed, Lisa A Moreau, Bartłomiej Tomasik, John A Tainer

Nat Struct Mol Biol· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis