Publications by authors named "Alejandro Brenes"

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Author Correction: Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity.
Manuel A Sanchez-Garcia, Pranvera Sadiku, Brian M Ortmann, Niek Wit, Yutaka Negishi, Alejandro J Brenes

Nat Immunol· December 2025

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Single cell proteomic analysis defines discrete neutrophil functional states in human glioblastoma.
Pranvera Sadiku, Alejandro J Brenes, Rupert L Mayer, Leila Reyes, Patricia Coelho

Nat Commun· December 2025

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Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity.
Manuel A Sanchez-Garcia, Pranvera Sadiku, Brian M Ortmann, Niek Wit, Yutaka Negishi, Alejandro J Brenes

Nat Immunol· November 2025

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Calculating and Reporting Coefficients of Variation for DIA-Based Proteomics.
Alejandro J Brenes

J Proteome Res· December 2024

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Deep proteomic analysis of microglia reveals fundamental biological differences between model systems.
Amy F Lloyd, Anna Martinez-Muriana, Emma Davis, Michael J D Daniels, Pengfei Hou, Alejandro J Brenes

Cell Rep· November 2024

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Proteomic and functional comparison between human induced and embryonic stem cells.
Alejandro J Brenes, Eva Griesser, Linda V Sinclair, Lindsay Davidson, Alan R Prescott

Elife· November 2024

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PROSER1 modulates DNA demethylation through dual mechanisms to prevent syndromic developmental malformations.
Anna Fleming, Elena V Knatko, Xiang Li, Ansgar Zoch, Zoe Heckhausen, Alejandro J Brenes

Genes Dev· November 2024

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Optimizing Spectronaut Search Parameters to Improve Data Quality with Minimal Proteome Coverage Reductions in DIA Analyses of Heterogeneous Samples.
Christa P Baker, Roland Bruderer, James Abbott, J Simon C Arthur, Alejandro J Brenes

J Proteome Res· June 2024

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Extensive acute and sustained changes to neutrophil proteomes post-SARS-CoV-2 infection.
Merete B Long, Andrew J M Howden, Holly R Keir, Christina M Rollings, Yan Hui Giam, Alejandro J Brenes

Eur Respir J· March 2024

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Quantitative proteomics reveals tissue-specific, infection-induced and species-specific neutrophil protein signatures.
Gabriel Sollberger, Alejandro J Brenes, Jordan Warner, J Simon C Arthur, Andrew J M Howden

Sci Rep· March 2024

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The Immunological Proteome Resource.
Alejandro J Brenes, Angus I Lamond, Doreen A Cantrell

Nat Immunol· May 2023

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DIA label-free proteomic analysis of murine bone-marrow-derived macrophages.
Christa P Baker, Iain R Phair, Alejandro J Brenes, Abdelmadjid Atrih, Dylan G Ryan

STAR Protoc· December 2022

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Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response.
Dylan G Ryan, Elena V Knatko, Alva M Casey, Jens L Hukelmann, Sharadha Dayalan Naidu, Alejandro J Brenes

iScience· February 2022

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Tissue environment, not ontogeny, defines murine intestinal intraepithelial T lymphocytes.
Alejandro J Brenes, Maud Vandereyken, Olivia J James, Harriet Watt, Jens Hukelmann

Elife· September 2021

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-------A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS--.
Leila Reyes, Manuel A Sanchez-Garcia, Tyler Morrison, Andy J M Howden, Emily R Watts, Alejandro J Brenes

Wellcome Open Res· May 2021

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Erosion of human X chromosome inactivation causes major remodeling of the iPSC proteome.
Alejandro J Brenes, Harunori Yoshikawa, Dalila Bensaddek, Bogdan Mirauta, Daniel Seaton

Cell Rep· April 2021

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Population-scale proteome variation in human induced pluripotent stem cells.
Bogdan Andrei Mirauta, Daniel D Seaton, Dalila Bensaddek, Alejandro Brenes, Marc Jan Bonder

Elife· August 2020

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Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation.
Andrew J M Howden, Jens L Hukelmann, Alejandro Brenes, Laura Spinelli, Linda V Sinclair

Nat Immunol· November 2019

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Multibatch TMT Reveals False Positives, Batch Effects and Missing Values.
Alejandro Brenes, Jens Hukelmann, Dalila Bensaddek, Angus I Lamond

Mol Cell Proteomics· October 2019

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The Encyclopedia of Proteome Dynamics: the KinoViewer.
Alejandro Brenes, Angus I Lamond

Bioinformatics· April 2019

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Antigen receptor control of methionine metabolism in T cells.
Linda V Sinclair, Andrew Jm Howden, Alejandro Brenes, Laura Spinelli, Jens L Hukelmann

Elife· March 2019

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Proteome-wide analysis of protein abundance and turnover remodelling during oncogenic transformation of human breast epithelial cells.
Tony Ly, Aki Endo, Alejandro Brenes, Marek Gierlinski, Vackar Afzal

Wellcome Open Res· May 2018

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The Encyclopedia of Proteome Dynamics: a big data ecosystem for (prote)omics.
Alejandro Brenes, Vackar Afzal, Robert Kent, Angus I Lamond

Nucleic Acids Res· January 2018

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