Publications by authors named "Alessandra Toti"

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Gut microbiota dysbiosis affects intestinal sensitivity through epithelium-to-neuron signaling: novel insights from a colon organoid-based model to improve visceral pain therapy.
Francesco Margiotta, Elena Lucarini, Alessandra Toti, Lorenzo Curti, Alessio Masi

Gut Microbes· December 2025

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In Vitro Study of Microbiota Influence on Enteric Glial Cell Physiology.
Elena Lucarini, Alessandra Toti

Methods Mol Biol· October 2025

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Biomarkers during early healing of extraction procedures: a prospective case series.
Alessandra Toti, Ada Kura, Elena Sticchi, Marco Duvina, Vanni Balestri

Clin Oral Investig· October 2025

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The challenge to identify sensitive safety biomarkers of peripheral neurotoxicity in the rat: A collaborative effort across industry and academia (IMI NeuroDeRisk project).
Laura Micheli, David Balayssac, Jérôme Busserolles, Cristelle Dalbos, Laetitia Prival, Alessandra Toti

Toxicology· January 2025

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Use of imidazo[1,5-a]quinoline scaffold as the pharmacophore in the design of bivalent ligands of central benzodiazepine receptors.
Marco Paolino, Mario Saletti, Jacopo Venditti, Federica Castriconi, Germano Giuliani, Alessandra Toti

Bioorg Med Chem· January 2025

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New insights in the mechanisms of opioid analgesia and tolerance: Ultramicronized palmitoylethanolamide down-modulates vascular endothelial growth factor-A in the nervous system.
Laura Micheli, Stefania Nobili, Elena Lucarini, Alessandra Toti, Francesco Margiotta

Pharmacol Res· November 2024

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Ultramicronized N-palmitoylethanolamine associated with analgesics: Effects against persistent pain.
Stefania Nobili, Laura Micheli, Elena Lucarini, Alessandra Toti, Carla Ghelardini

Pharmacol Ther· June 2024

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Correction: VEGF-A/VEGFR-1 signalling and chemotherapy-induced neuropathic pain: therapeutic potential of a novel anti-VEGFR-1 monoclonal antibody.
Laura Micheli, Carmen Parisio, Elena Lucarini, Alessia Vona, Alessandra Toti

J Exp Clin Cancer Res· April 2024

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Ultramicronized -palmitoylethanolamine Contributes to Morphine Efficacy Against Neuropathic Pain: Implication of Mast Cells and Glia.
Laura Micheli, Elena Lucarini, Stefania Nobili, Gianluca Bartolucci, Marco Pallecchi, Alessandra Toti

Curr Neuropharmacol· November 2023

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Anti-Hyperalgesic Efficacy of Acetyl L-Carnitine (ALCAR) Against Visceral Pain Induced by Colitis: Involvement of Glia in the Enteric and Central Nervous System.
Elena Lucarini, Laura Micheli, Alessandra Toti, Clara Ciampi, Francesco Margiotta

Int J Mol Sci· October 2023

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Protective and Pain-Killer Effects of AMC3, a Novel N-Formyl Peptide Receptors (FPRs) Modulator, in Experimental Models of Rheumatoid Arthritis.
Valentina Ferrara, Alessandra Toti, Elena Lucarini, Carmen Parisio, Laura Micheli

Antioxidants (Basel)· June 2023

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Ultramicronized -Palmitoylethanolamine Regulates Mast Cell-Astrocyte Crosstalk: A New Potential Mechanism Underlying the Inhibition of Morphine Tolerance.
Alessandra Toti, Laura Micheli, Elena Lucarini, Valentina Ferrara, Clara Ciampi

Biomolecules· January 2023

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The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII.
Alessandro Bonardi, Silvia Bua, Jacob Combs, Carrie Lomelino, Jacob Andring, Alessandra Toti

J Enzyme Inhib Med Chem· December 2022

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Interferon-gamma and neuropathy: balance between pain and neuroprotection.
Valentina Ferrara, Alessandra Toti, Carla Ghelardini, Lorenzo Di Cesare Mannelli

Neural Regen Res· December 2022

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Efficacy of a vegetal mixture composed of , , and in a mouse model of neuroinflammation: and analysis.
Laura Micheli, Alessandra Toti, Elena Lucarini, Valentina Ferrara, Clara Ciampi

Front Nutr· August 2022

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Inhibition of Monoacylglycerol Lipase by NSD1819 as an Effective Strategy for the Endocannabinoid System Modulation against Neuroinflammation-Related Disorders.
Laura Micheli, Samuele Maramai, Alessandra Toti, Valentina Ferrara, Clara Ciampi

Int J Mol Sci· July 2022

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The Efficacy of Defatted Seed Meal against Colitis-Induced Persistent Visceral Hypersensitivity: The Relevance of PPAR α Receptor Activation in Pain Relief.
Elena Lucarini, Laura Micheli, Eleonora Pagnotta, Alessandra Toti, Valentina Ferrara

Nutrients· July 2022

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Neuronal alarmin IL-1α evokes astrocyte-mediated protective signals: Effectiveness in chemotherapy-induced neuropathic pain.
Lorenzo Di Cesare Mannelli, Laura Micheli, Chiara Cervetto, Alessandra Toti, Elena Lucarini

Neurobiol Dis· June 2022

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Restorative and pain-relieving effects of fibroin in preclinical models of tendinopathy.
Laura Micheli, Carmen Parisio, Elena Lucarini, Donatello Carrino, Clara Ciampi, Alessandra Toti

Biomed Pharmacother· April 2022

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Beneficial Effects of Defatted Seed Meal on Visceral Pain and Intestinal Damage Resulting from Colitis in Rats.
Elena Lucarini, Laura Micheli, Eleonora Pagnotta, Roberto Matteo, Carmen Parisio, Alessandra Toti

Foods· February 2022

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Effects of Ultramicronized -Palmitoylethanolamine Supplementation on Tramadol and Oxycodone Analgesia and Tolerance Prevention.
Laura Micheli, Elena Lucarini, Alessandra Toti, Valentina Ferrara, Clara Ciampi

Pharmaceutics· February 2022

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Role of Enteric Glia as Bridging Element between Gut Inflammation and Visceral Pain Consolidation during Acute Colitis in Rats.
Elena Lucarini, Luisa Seguella, Martina Vincenzi, Carmen Parisio, Laura Micheli, Alessandra Toti

Biomedicines· November 2021

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VEGF-A/VEGFR-1 signalling and chemotherapy-induced neuropathic pain: therapeutic potential of a novel anti-VEGFR-1 monoclonal antibody.
Laura Micheli, Carmen Parisio, Elena Lucarini, Alessia Vona, Alessandra Toti

J Exp Clin Cancer Res· October 2021

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Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in Rats.
Elena Lucarini, Alessio Nocentini, Alessandro Bonardi, Niccolò Chiaramonte, Carmen Parisio, Alessandra Toti

Cells· September 2021

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Lipid Cubic Mesophases Combined with Superparamagnetic Iron Oxide Nanoparticles: A Hybrid Multifunctional Platform with Tunable Magnetic Properties for Nanomedical Applications.
Lucrezia Caselli, Marco Mendozza, Beatrice Muzzi, Alessandra Toti, Costanza Montis

Int J Mol Sci· August 2021

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