Publications by authors named "Niccolo Chiaramonte"

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2
2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity.
Niccolò Chiaramonte, Andrea Angeli, Silvia Sgambellone, Alessandro Bonardi, Alessio Nocentini

Eur J Med Chem· January 2022

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New Histamine-Related Five-Membered N-Heterocycle Derivatives as Carbonic Anhydrase I Activators.
Niccolò Chiaramonte, Alessio Gabellini, Andrea Angeli, Gianluca Bartolucci, Laura Braconi

Molecules· January 2022

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Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in Rats.
Elena Lucarini, Alessio Nocentini, Alessandro Bonardi, Niccolò Chiaramonte, Carmen Parisio

Cells· September 2021

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6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline amides and corresponding ester isosteres as multidrug resistance reversers.
Laura Braconi, Gianluca Bartolucci, Marialessandra Contino, Niccolò Chiaramonte, Roberta Giampietro

J Enzyme Inhib Med Chem· December 2020

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Synthesis and carbonic anhydrase activating properties of a series of 2-amino-imidazolines structurally related to clonidine.
Niccolò Chiaramonte, Soumia Maach, Caterina Biliotti, Andrea Angeli, Gianluca Bartolucci

J Enzyme Inhib Med Chem· December 2020

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Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors.
Niccolò Chiaramonte, Silvia Bua, Andrea Angeli, Marta Ferraroni, Ilaria Picchioni

Bioorg Chem· October 2019

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Modulation of the spacer in N,N-bis(alkanol)amine aryl ester heterodimers led to the discovery of a series of highly potent P-glycoprotein-based multidrug resistance (MDR) modulators.
Silvia Dei, Laura Braconi, Alfonso Trezza, Marta Menicatti, Marialessandra Contino, Niccolò Chiaramonte

Eur J Med Chem· June 2019

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New Rigid Nicotine Analogues, Carrying a Norbornane Moiety, Are Potent Agonists of α7 and α3* Nicotinic Receptors.
Dina Manetti, Alexandra Garifulina, Gianluca Bartolucci, Carla Bazzicalupi, Cristina Bellucci, Niccolò Chiaramonte

J Med Chem· February 2019

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Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators.
Andrea Angeli, Niccolò Chiaramonte, Dina Manetti, Maria Novella Romanelli, Claudiu T Supuran

J Enzyme Inhib Med Chem· December 2018

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2
2-Benzylpiperazine: A new scaffold for potent human carbonic anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents.
Niccolò Chiaramonte, Silvia Bua, Marta Ferraroni, Alessio Nocentini, Alessandro Bonardi

Eur J Med Chem· May 2018

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Amino Acids as Building Blocks for Carbonic Anhydrase Inhibitors.
Niccolò Chiaramonte, Maria Novella Romanelli, Elisabetta Teodori, Claudiu T Supuran

Metabolites· May 2018

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Designing selective modulators for the nicotinic receptor subtypes: challenges and opportunities.
Dina Manetti, Cristina Bellucci, Niccolò Chiaramonte, Silvia Dei, Elisabetta Teodori

Future Med Chem· February 2018

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Design and synthesis of aminoester heterodimers containing flavone or chromone moieties as modulators of P-glycoprotein-based multidrug resistance (MDR).
Silvia Dei, Maria Novella Romanelli, Dina Manetti, Niccolò Chiaramonte, Marcella Coronnello

Bioorg Med Chem· January 2018

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