Publications by authors named "Alessandro Romanel"

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HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences.
Fabio Mazza, Filippo Gastaldello, Davide Dalfovo, Gianluca Lattanzi, Alessandro Romanel

Nucleic Acids Res· November 2025

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TRPM8 levels determine tumor vulnerability to channel agonists.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Alessandro Romanel

Mol Oncol· October 2025

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Integrative Computational Analysis of Common EXO5 Haplotypes: Impact on Protein Dynamics, Genome Stability, and Cancer Progression.
Fabio Mazza, Davide Dalfovo, Alessio Bartocci, Gianluca Lattanzi, Alessandro Romanel

J Chem Inf Model· April 2025

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Enabling sensitive and precise detection of ctDNA through somatic copy number aberrations in breast cancer.
Riccardo Scandino, Agostina Nardone, Nicola Casiraghi, Francesca Galardi, Mattia Genovese, Alessandro Romanel

NPJ Breast Cancer· March 2025

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Rarγ-Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer.
Dario De Felice, Alessandro Alaimo, Davide Bressan, Sacha Genovesi, Elisa Marmocchi, Alessandro Romanel

EMBO Rep· January 2025

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The three YTHDF paralogs and VIRMA are strong cross-histotype tumor driver candidates among mA core genes.
Eliana Destefanis, Denise Sighel, Davide Dalfovo, Riccardo Gilmozzi, Francesca Broso, Alessandro Romanel

NAR Cancer· December 2024

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SpikeFlow: automated and flexible analysis of ChIP-Seq data with spike-in control.
Davide Bressan, Daniel Fernández-Pérez, Alessandro Romanel, Fulvio Chiacchiera

NAR Genom Bioinform· September 2024

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Correction: PaCBAM: fast and scalable processing of whole exome and targeted sequencing data.
Samuel Valentini, Tarcisio Fedrizzi, Francesca Demichelis, Alessandro Romanel

BMC Genomics· May 2024

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Sterile inflammation via TRPM8 RNA-dependent TLR3-NF-kB/IRF3 activation promotes antitumor immunity in prostate cancer.
Alessandro Alaimo, Sacha Genovesi, Nicole Annesi, Dario De Felice, Saurav Subedi, Alessandro Romanel

EMBO J· March 2024

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Germline determinants of aberrant signaling pathways in cancer.
Davide Dalfovo, Riccardo Scandino, Marta Paoli, Samuel Valentini, Alessandro Romanel

NPJ Precis Oncol· March 2024

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Increased genomic instability and reshaping of tissue microenvironment underlie oncogenic properties of mutations.
Alessandro D'Ambrosio, Davide Bressan, Elisa Ferracci, Francesco Carbone, Patrizia Mulè, Alessandro Romanel

Sci Adv· March 2024

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Rarγ -Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer.
Dario De Felice, Alessandro Alaimo, Davide Bressan, Sacha Genovesi, Elisa Marmocchi, Alessandro Romanel

bioRxiv· March 2024

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Divergent HLA variations and heterogeneous expression but recurrent HLA loss-of- heterozygosity and common and transcriptional silencing across advanced pediatric solid cancers.
Wan Ching Lim, Maria Eugenia Marques Da Costa, Karine Godefroy, Eric Jacquet, Loren Gragert, Alessandro Romanel

Front Immunol· February 2024

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LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice.
Ramachandran Prakasam, Angela Bonadiman, Roberta Andreotti, Emanuela Zuccaro, Davide Dalfovo, Alessandro Romanel

Nat Commun· February 2023

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Analysis of Genetic Ancestry from NGS Data Using EthSEQ.
Davide Dalfovo, Alessandro Romanel

Curr Protoc· February 2023

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Synggen: fast and data-driven generation of synthetic heterogeneous NGS cancer data.
Riccardo Scandino, Federico Calabrese, Alessandro Romanel

Bioinformatics· January 2023

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Transient rapamycin treatment during developmental stage extends lifespan in Mus musculus and Drosophila melanogaster.
Giuseppe Aiello, Cosimo Sabino, Davide Pernici, Matteo Audano, Francesco Antonica, Alessandro Romanel

EMBO Rep· September 2022

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A slow-cycling/quiescent cells subpopulation is involved in glioma invasiveness.
Francesco Antonica, Lucia Santomaso, Davide Pernici, Linda Petrucci, Giuseppe Aiello, Alessandro Romanel

Nat Commun· August 2022

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Allele-informed copy number evaluation of plasma DNA samples from metastatic prostate cancer patients: the PCF_SELECT consortium assay.
Francesco Orlando, Alessandro Romanel, Blanca Trujillo, Michael Sigouros, Daniel Wetterskog

NAR Cancer· June 2022

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Intra-epithelial non-canonical Activin A signaling safeguards prostate progenitor quiescence.
Francesco Cambuli, Veronica Foletto, Alessandro Alaimo, Dario De Felice, Francesco Gandolfi, Alessandro Romanel

EMBO Rep· May 2022

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ETS-related gene (ERG) undermines genome stability in mouse prostate progenitors via Gsk3β dependent Nkx3.1 degradation.
Marco Lorenzoni, Dario De Felice, Giulia Beccaceci, Giorgia Di Donato, Veronica Foletto, Alessandro Romanel

Cancer Lett· May 2022

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Plasma tumor DNA is associated with increased risk of venous thromboembolism in metastatic castration-resistant cancer patients.
Vincenza Conteduca, Emanuela Scarpi, Daniel Wetterskog, Nicole Brighi, Fabio Ferroni, Alessandro Romanel

Int J Cancer· April 2022

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Polympact: exploring functional relations among common human genetic variants.
Samuel Valentini, Francesco Gandolfi, Mattia Carolo, Davide Dalfovo, Lara Pozza, Alessandro Romanel

Nucleic Acids Res· February 2022

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and Amplifications as Synergistic Resistance Mechanisms to Different Generation ALK Tyrosine Kinase Inhibitors in Advanced NSCLC: Brief Report of Clinical and Preclinical Proofs.
Roberta Minari, Samuel Valentini, Denise Madeddu, Andrea Cavazzoni, Silvia La Monica, Alessandro Romanel

JTO Clin Res Rep· February 2022

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: A class of functional SNPs affecting mRNA translation potential revealed by fraction-based allelic imbalance.
Samuel Valentini, Caterina Marchioretti, Alessandra Bisio, Annalisa Rossi, Sara Zaccara, Alessandro Romanel

iScience· December 2021

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