Publications by authors named "Alessia Cavazza"

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Unveiling the cut-and-repair cycle of designer nucleases in human stem and T cells via CLEAR-time dPCR.
Nathan White, John Alexander Chalk, Yi-Ting Hu, Samuel Mark Pins, Chinnu Rose Joseph, Alessia Cavazza

Nat Commun· November 2025

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Proceedings of the second annual meeting of GenE-HumDi (COST Action 21113).
María Ortiz-Bueno, Iris Ramos-Hernández, Luis Algeciras-Jiménez, Nechama Kalter, Juan Roberto Rodríguez-Madoz, Alessia Cavazza

Front Genome Ed· November 2025

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Advanced delivery systems for gene editing: A comprehensive review from the GenE-HumDi COST Action Working Group.
Alessia Cavazza, Francisco J Molina-Estévez, Álvaro Plaza Reyes, Victor Ronco, Asma Naseem

Mol Ther Nucleic Acids· March 2025

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The future of ex vivo hematopoietic stem cell gene editing: what's next.
Alessia Cavazza, Giorgia Santilli

Regen Med· March 2025

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Hematopoietic stem cell gene editing rescues B-cell development in X-linked agammaglobulinemia.
Sameer Bahal, Marta Zinicola, Shefta E Moula, Thomas E Whittaker, Andrea Schejtman, Alessia Cavazza

J Allergy Clin Immunol· July 2024

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It's all about location: Targeting the right spot for Wiskott-Aldrich syndrome.
Asma Naseem, Alessia Cavazza

Mol Ther Methods Clin Dev· June 2024

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Multidimensional Response Surface Methodology for the Development of a Gene Editing Protocol for p67-Deficient Chronic Granulomatous Disease.
Thomas E Whittaker, Shefta E Moula, Sameer Bahal, Faris Ghalib Bakri, Wail Ahmad Hayajneh, Alessia Cavazza

Hum Gene Ther· April 2024

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CRISPR/Cas9-Based Disease Modeling and Functional Correction of Interleukin 7 Receptor Alpha Severe Combined Immunodeficiency in T-Lymphocytes and Hematopoietic Stem Cells.
Rajeev Rai, Zohar Steinberg, Marianna Romito, Federica Zinghirino, Yi-Ting Hu, Alessia Cavazza

Hum Gene Ther· April 2024

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Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi.
Alessia Cavazza, Ayal Hendel, Rasmus O Bak, Paula Rio, Marc Güell

Mol Ther Nucleic Acids· December 2023

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An improved medium formulation for efficient gene editing, expansion and engraftment of hematopoietic stem and progenitor cells.
Rajeev Rai, Asma Naseem, Winston Vetharoy, Zohar Steinberg, Adrian J Thrasher, Alessia Cavazza

Mol Ther Methods Clin Dev· June 2023

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Genome editing for primary immunodeficiencies: A therapeutic perspective on Wiskott-Aldrich syndrome.
Asma Naseem, Zohar Steinberg, Alessia Cavazza

Front Immunol· September 2022

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Gene Editing for the Treatment of Primary Immunodeficiency Diseases.
Rajeev Rai, Adrian J Thrasher, Alessia Cavazza

Hum Gene Ther· January 2021

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Gene Editing and Genotoxicity: Targeting the Off-Targets.
Georges Blattner, Alessia Cavazza, Adrian J Thrasher, Giandomenico Turchiano

Front Genome Ed· December 2020

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Wiskott Aldrich syndrome protein regulates non-selective autophagy and mitochondrial homeostasis in human myeloid cells.
Elizabeth Rivers, Rajeev Rai, Jonas Lötscher, Michael Hollinshead, Gasper Markelj, Alessia Cavazza

Elife· November 2020

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Targeted gene correction of human hematopoietic stem cells for the treatment of Wiskott - Aldrich Syndrome.
Rajeev Rai, Marianna Romito, Elizabeth Rivers, Giandomenico Turchiano, Georges Blattner, Alessia Cavazza

Nat Commun· August 2020

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Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells.
Kazutaka Murata, Unmesh Jadhav, Shariq Madha, Johan van Es, Justin Dean, Alessia Cavazza

Cell Stem Cell· March 2020

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Enhancing Lentiviral and Alpharetroviral Transduction of Human Hematopoietic Stem Cells for Clinical Application.
Juliane W Schott, Diego León-Rico, Carolina B Ferreira, Karen F Buckland, Giorgia Santilli, Alessia Cavazza

Mol Ther Methods Clin Dev· September 2019

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Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in Hypomethylated Enhancer DNA.
Unmesh Jadhav, Alessia Cavazza, Kushal K Banerjee, Huafeng Xie, Nicholas K O'Neill

Mol Cell· May 2019

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Genome editing for blood disorders: state of the art and recent advances.
Marianna Romito, Rajeev Rai, Adrian J Thrasher, Alessia Cavazza

Emerg Top Life Sci· May 2019

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Enhancer, transcriptional, and cell fate plasticity precedes intestinal determination during endoderm development.
Kushal K Banerjee, Madhurima Saxena, Namit Kumar, Lei Chen, Alessia Cavazza

Genes Dev· November 2018

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Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells.
Pamela P Lee, Damián Lobato-Márquez, Nayani Pramanik, Andrea Sirianni, Vanessa Daza-Cajigal, Alessia Cavazza

Nat Commun· November 2017

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Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype.
Paloma Cejas, Alessia Cavazza, C N Yandava, Victor Moreno, David Horst

Cancer Res· February 2017

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Single-Cell Transcript Profiles Reveal Multilineage Priming in Early Progenitors Derived from Lgr5(+) Intestinal Stem Cells.
Tae-Hee Kim, Assieh Saadatpour, Guoji Guo, Madhurima Saxena, Alessia Cavazza

Cell Rep· August 2016

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Dynamic Transcriptional and Epigenetic Regulation of Human Epidermal Keratinocyte Differentiation.
Alessia Cavazza, Annarita Miccio, Oriana Romano, Luca Petiti, Guidantonio Malagoli Tagliazucchi

Stem Cell Reports· April 2016

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Transcriptional, epigenetic and retroviral signatures identify regulatory regions involved in hematopoietic lineage commitment.
Oriana Romano, Clelia Peano, Guidantonio Malagoli Tagliazucchi, Luca Petiti, Valentina Poletti, Alessia Cavazza

Sci Rep· April 2016

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