Publications by authors named "Unmesh Jadhav"

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A niche-dependent redox rheostat regulates epithelial stem cell fate.
Xi Chen, Krishnan Raghunathan, Bin Bao, Elsy Ngwa, Andrew Kwong, Unmesh Jadhav

Nat Commun· November 2025

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Crypt density and recruited enhancers underlie intestinal tumour initiation.
Liam Gaynor, Harshabad Singh, Guodong Tie, Krithika Badarinath, Shariq Madha, Unmesh Jadhav

Nature· April 2025

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Motif distribution and DNA methylation underlie distinct Cdx2 binding during development and homeostasis.
Alireza Lorzadeh, George Ye, Sweta Sharma, Unmesh Jadhav

Nat Commun· January 2025

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DNA methylation-dependent and -independent binding of CDX2 directs activation of distinct developmental and homeostatic genes.
Alireza Lorzadeh, George Ye, Sweta Sharma, Unmesh Jadhav

bioRxiv· March 2024

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Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer.
Min-Sik Lee, Courtney Dennis, Insia Naqvi, Lucas Dailey, Alireza Lorzadeh, Unmesh Jadhav

Nature· April 2023

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Epigenetic Regulation of Intestinal Stem Cells and Disease: A Balancing Act of DNA and Histone Methylation.
Alireza Lorzadeh, Maile Romero-Wolf, Ajay Goel, Unmesh Jadhav

Gastroenterology· June 2021

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Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1.
Pei-Yun Tsai, Min-Sik Lee, Unmesh Jadhav, Insia Naqvi, Shariq Madha

Proc Natl Acad Sci U S A· March 2021

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Creb5 establishes the competence for Prg4 expression in articular cartilage.
Cheng-Hai Zhang, Yao Gao, Unmesh Jadhav, Han-Hwa Hung, Kristina M Holton

Commun Biol· March 2021

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Replicational Dilution of H3K27me3 in Mammalian Cells and the Role of Poised Promoters.
Unmesh Jadhav, Elisa Manieri, Kodandaramireddy Nalapareddy, Shariq Madha, Shaon Chakrabarti

Mol Cell· April 2020

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Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells.
Kazutaka Murata, Unmesh Jadhav, Shariq Madha, Johan van Es, Justin Dean

Cell Stem Cell· March 2020

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Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in Hypomethylated Enhancer DNA.
Unmesh Jadhav, Alessia Cavazza, Kushal K Banerjee, Huafeng Xie, Nicholas K O'Neill

Mol Cell· May 2019

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Dissecting Cell Lineages: From Microscope to Kaleidoscope.
Unmesh Jadhav, Ramesh A Shivdasani

Cell· February 2019

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Enhancer, transcriptional, and cell fate plasticity precedes intestinal determination during endoderm development.
Kushal K Banerjee, Madhurima Saxena, Namit Kumar, Lei Chen, Alessia Cavazza, Unmesh Jadhav

Genes Dev· November 2018

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RORα-expressing T regulatory cells restrain allergic skin inflammation.
Nidhi Malhotra, Juan Manuel Leyva-Castillo, Unmesh Jadhav, Olga Barreiro, Christy Kam

Sci Immunol· March 2018

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Transcription factor-dependent 'anti-repressive' mammalian enhancers exclude H3K27me3 from extended genomic domains.
Madhurima Saxena, Adrianna K San Roman, Nicholas K O'Neill, Rita Sulahian, Unmesh Jadhav

Genes Dev· December 2017

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Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells.
Unmesh Jadhav, Madhurima Saxena, Nicholas K O'Neill, Assieh Saadatpour, Guo-Cheng Yuan

Cell Stem Cell· July 2017

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Natural Selection, Crypt Fitness, and Pol III Dependency in the Intestine.
Unmesh Jadhav, Ramesh A Shivdasani

Cell Mol Gastroenterol Hepatol· November 2016

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Single-Cell Transcript Profiles Reveal Multilineage Priming in Early Progenitors Derived from Lgr5(+) Intestinal Stem Cells.
Tae-Hee Kim, Assieh Saadatpour, Guoji Guo, Madhurima Saxena, Alessia Cavazza, Unmesh Jadhav

Cell Rep· August 2016

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Acquired Tissue-Specific Promoter Bivalency Is a Basis for PRC2 Necessity in Adult Cells.
Unmesh Jadhav, Kodandaramireddy Nalapareddy, Madhurima Saxena, Nicholas K O'Neill, Luca Pinello

Cell· June 2016

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SOX15 governs transcription in human stratified epithelia and a subset of esophageal adenocarcinomas.
Rita Sulahian, Justina Chen, Zoltan Arany, Unmesh Jadhav, Shouyong Peng

Cell Mol Gastroenterol Hepatol· November 2015

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Hypogonadotropic hypogonadism in subjects with DAX1 mutations.
Unmesh Jadhav, Rebecca M Harris, J Larry Jameson

Mol Cell Endocrinol· October 2011

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Steroidogenic factor-1 (SF-1)-driven differentiation of murine embryonic stem (ES) cells into a gonadal lineage.
Unmesh Jadhav, J Larry Jameson

Endocrinology· July 2011

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The hemopexin domain of MMP-9 inhibits angiogenesis and retards the growth of intracranial glioblastoma xenograft in nude mice.
Ravesanker Ezhilarasan, Unmesh Jadhav, Indra Mohanam, Jasti S Rao, Meena Gujrati

Int J Cancer· January 2009

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Iberin induces cell cycle arrest and apoptosis in human neuroblastoma cells.
Unmesh Jadhav, Ravesanker Ezhilarasan, Steven F Vaughn, Mark A Berhow, Sanjeeva Mohanam

Int J Mol Med· March 2007

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Dietary isothiocyanate iberin inhibits growth and induces apoptosis in human glioblastoma cells.
Unmesh Jadhav, Ravesanker Ezhilarasan, Steven F Vaughn, Mark A Berhow, Sanjeeva Mohanam

J Pharmacol Sci· February 2007

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