Publications by authors named "Alex Crowe"

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HDAC6 Inhibition Reduces Seeded Tau and α-Synuclein Pathologies in Primary Neuron Cultures and Wild-type Mice.
Alex Crowe, Yuemang Yao, Mira Newman, Kevt'her Hoxha, Thallyah Baffic

J Neurosci· December 2025

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Targeting Endogenous Tau in Seeded Tauopathy Models Inhibits Tau Spread.
Elliot Jang, Kevt'her Hoxha, Damian Mozier, Abigail Insana, Ethan Farber, Alex Crowe

J Neurosci· November 2024

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Identification of small molecules and related targets that modulate tau pathology in a seeded primary neuron model.
Garrett S Gibbons, Hailey Gould, Virginia M-Y Lee, Alex Crowe, Kurt R Brunden

J Biol Chem· July 2023

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Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays.
Alex Crowe, Mark J Henderson, Johnathon Anderson, Steven A Titus, Alexey Zakharov

J Biol Chem· March 2020

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Tuberous Sclerosis Complex (TSC): Expert Recommendations for Provision of Coordinated Care.
Nicholas M P Annear, Richard E Appleton, Zahabiyah Bassi, Rupesh Bhatt, Patrick F Bolton, Alex Crowe

Front Neurol· November 2019

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The Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES.
Jing L Guo, Arjan Buist, Alberto Soares, Kathleen Callaerts, Sara Calafate, Alex Crowe

J Biol Chem· June 2016

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Design, synthesis, and biological evaluation of 1-phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as new glycogen synthase kinase-3β inhibitors.
Valeria La Pietra, Giuseppe La Regina, Antonio Coluccia, Valeria Famiglini, Sveva Pelliccia, Alex Crowe

J Med Chem· December 2013

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Developing an online, modular, active learning training program for behavioral activation.
Ajeng Puspitasari, Jonathan W Kanter, Joseph Murphy, Alex Crowe, Kelly Koerner

Psychotherapy (Chic)· June 2013

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Aminothienopyridazines and methylene blue affect Tau fibrillization via cysteine oxidation.
Alex Crowe, Michael J James, Virginia M-Y Lee, Amos B Smith, John Q Trojanowski

J Biol Chem· April 2013

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Aminothienopyridazine inhibitors of tau aggregation: evaluation of structure-activity relationship leads to selection of candidates with desirable in vivo properties.
Carlo Ballatore, Alex Crowe, Francesco Piscitelli, Michael James, Kevin Lou

Bioorg Med Chem· July 2012

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Tau-directed drug discovery for Alzheimer's disease and related tauopathies: a focus on tau assembly inhibitors.
Kurt R Brunden, Carlo Ballatore, Alex Crowe, Amos B Smith, Virginia M-Y Lee

Exp Neurol· June 2010

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Discovery of brain-penetrant, orally bioavailable aminothienopyridazine inhibitors of tau aggregation.
Carlo Ballatore, Kurt R Brunden, Francesco Piscitelli, Michael J James, Alex Crowe

J Med Chem· May 2010

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Lanthanum associated abnormal liver function tests in two patients on dialysis: a case report.
Girish Namagondlu, Norman Main, Lucy Yates, Joanne Mooney, Sangita Sathyamurthy, Alex Crowe

J Med Case Rep· December 2009

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Case mix, outcome and activity for patients with severe acute kidney injury during the first 24 hours after admission to an adult, general critical care unit: application of predictive models from a secondary analysis of the ICNARC Case Mix Programme database.
Nitin V Kolhe, Paul E Stevens, Alex V Crowe, Graham W Lipkin, David A Harrison

Crit Care· November 2009

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Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau.
Wenkai Li, Jeffrey B Sperry, Alex Crowe, John Q Trojanowski, Amos B Smith

J Neurochem· August 2009

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Identification of aminothienopyridazine inhibitors of tau assembly by quantitative high-throughput screening.
Alex Crowe, Wenwei Huang, Carlo Ballatore, Ronald L Johnson, Anne-Marie L Hogan

Biochemistry· August 2009

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Ventriculo-peritoneal shunt infection in a patient on hemodialysis.
Yupar Thet, Win Myint, David Hughes, Alex V Crowe, Anindya Banerjee

Hemodial Int· July 2008

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Case mix, outcome and activity for patients admitted to intensive care units requiring chronic renal dialysis: a secondary analysis of the ICNARC Case Mix Programme Database.
Colin A Hutchison, Alex V Crowe, Paul E Stevens, David A Harrison, Graham W Lipkin

Crit Care· February 2008

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High throughput screening for small molecule inhibitors of heparin-induced tau fibril formation.
Alex Crowe, Carlo Ballatore, Edward Hyde, John Q Trojanowski, Virginia M-Y Lee

Biochem Biophys Res Commun· June 2007

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Biochemical and pathological characterization of frontotemporal dementia due to a Leu266Val mutation in microtubule-associated protein tau in an African American individual.
Vivianna M Van Deerlin, Mark S Forman, Jennifer M Farmer, Murray Grossman, Sonali Joyce, Alex Crowe

Acta Neuropathol· April 2007

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Surviving and thriving in the early years as a new consultant physician.
Alex Crowe

Clin Med (Lond)· July 2004

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An English kindred with a novel recessive tauopathy and respiratory failure.
David J Nicholl, Michael A Greenstone, Carl E Clarke, Patrizia Rizzu, Daniel Crooks, Alex Crowe

Ann Neurol· November 2003

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Treatment of haemodialysis catheter-related infections.
Anand Vardhan, Jon Davies, Indiver Daryanani, Alex Crowe, Peter McClelland

Nephrol Dial Transplant· June 2002

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