Publications by authors named "Alex D Sheftel"

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Human CIA2A-FAM96A and CIA2B-FAM96B Integrate Iron Homeostasis and Maturation of Different Subsets of Cytosolic-Nuclear Iron-Sulfur Proteins.
Oliver Stehling, Judita Mascarenhas, Ajay A Vashisht, Alex D Sheftel, Brigitte Niggemeyer

Cell Metab· January 2018

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Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells.
Daniel Garcia-Santos, Matthias Schranzhofer, Richard Bergeron, Alex D Sheftel, Prem Ponka

Haematologica· August 2017

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Do Mammalian Cells Really Need to Export and Import Heme?
Prem Ponka, Alex D Sheftel, Ann M English, D Scott Bohle, Daniel Garcia-Santos

Trends Biochem Sci· May 2017

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Erythroid cell mitochondria receive endosomal iron by a "kiss-and-run" mechanism.
Amel Hamdi, Tariq M Roshan, Tanya M Kahawita, Anne B Mason, Alex D Sheftel

Biochim Biophys Acta· December 2016

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Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation.
Zhen-Hua Shi, Fang-Fang Shi, Yue-Qi Wang, Alex D Sheftel, Guangjun Nie

Cell Mol Life Sci· March 2015

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Prognostic usefulness of insulin-like growth factor-binding protein 7 in heart failure with reduced ejection fraction: a novel biomarker of myocardial diastolic function?
Parul U Gandhi, Hanna K Gaggin, Alex D Sheftel, Arianna M Belcher, Rory B Weiner

Am J Cardiol· November 2014

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Heme oxygenase 1 is expressed in murine erythroid cells where it controls the level of regulatory heme.
Daniel Garcia-Santos, Matthias Schranzhofer, Monika Horvathova, Mehrad Mojtahed Jaberi, Jose Artur Bogo Chies, Alex D Sheftel

Blood· April 2014

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HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress.
Liyong Zhang, Xin Chen, Parveen Sharma, Mark Moon, Alex D Sheftel

Nat Commun· March 2014

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Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.
Oliver Stehling, Judita Mascarenhas, Ajay A Vashisht, Alex D Sheftel, Brigitte Niggemeyer

Cell Metab· August 2013

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The human mitochondrial ISCA1, ISCA2, and IBA57 proteins are required for [4Fe-4S] protein maturation.
Alex D Sheftel, Claudia Wilbrecht, Oliver Stehling, Brigitte Niggemeyer, Hans-Peter Elsässer

Mol Biol Cell· April 2012

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The long history of iron in the Universe and in health and disease.
Alex D Sheftel, Anne B Mason, Prem Ponka

Biochim Biophys Acta· March 2012

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Ferritin does not donate its iron for haem synthesis in macrophages.
Marc Mikhael, Alex D Sheftel, Prem Ponka

Biochem J· August 2010

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Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol.
Des R Richardson, Darius J R Lane, Erika M Becker, Michael L-H Huang, Megan Whitnall, Alex D Sheftel

Proc Natl Acad Sci U S A· June 2010

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Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis.
Alex D Sheftel, Oliver Stehling, Antonio J Pierik, Hans-Peter Elsässer, Ulrich Mühlenhoff

Proc Natl Acad Sci U S A· June 2010

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Human ind1, an iron-sulfur cluster assembly factor for respiratory complex I.
Alex D Sheftel, Oliver Stehling, Antonio J Pierik, Daili J A Netz, Stefan Kerscher

Mol Cell Biol· November 2009

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Mitochondrial iron metabolism and sideroblastic anemia.
Alex D Sheftel, Des R Richardson, Josef Prchal, Prem Ponka

Acta Haematol· November 2009

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Chapter 12 Controlled expression of iron-sulfur cluster assembly components for respiratory chain complexes in mammalian cells.
Oliver Stehling, Alex D Sheftel, Roland Lill

Methods Enzymol· June 2009

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The power plant of the cell is also a smithy: the emerging role of mitochondria in cellular iron homeostasis.
Alex D Sheftel, Roland Lill

Ann Med· April 2009

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Nramp1 equips macrophages for efficient iron recycling.
Shan Soe-Lin, Alex D Sheftel, Brandi Wasyluk, Prem Ponka

Exp Hematol· August 2008

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Direct interorganellar transfer of iron from endosome to mitochondrion.
Alex D Sheftel, An-Sheng Zhang, Claire Brown, Orian S Shirihai, Prem Ponka

Blood· July 2007

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Non-heme induction of heme oxygenase-1 does not alter cellular iron metabolism.
Alex D Sheftel, Sangwon F Kim, Prem Ponka

J Biol Chem· April 2007

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In vivo tumor growth is inhibited by cytosolic iron deprivation caused by the expression of mitochondrial ferritin.
Guangjun Nie, Guohua Chen, Alex D Sheftel, Kostas Pantopoulos, Prem Ponka

Blood· October 2006

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Iron regulatory protein-independent regulation of ferritin synthesis by nitrogen monoxide.
Marc Mikhael, Sangwon F Kim, Matthias Schranzhofer, Shan Soe-Lin, Alex D Sheftel

FEBS J· August 2006

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The anemia of "haemoglobin-deficit" (hbd/hbd) mice is caused by a defect in transferrin cycling.
An-Sheng Zhang, Alex D Sheftel, Prem Ponka

Exp Hematol· May 2006

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Functional consequences of the human DMT1 (SLC11A2) mutation on protein expression and iron uptake.
Monika Priwitzerova, Guangjun Nie, Alex D Sheftel, Dagmar Pospisilova, Vladimir Divoky

Blood· December 2005

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