Publications by authors named "Prem Ponka"

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Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin.
Pei Jin Lim, Tiago L Duarte, João Arezes, Daniel Garcia-Santos, Amel Hamdi, Prem Ponka

Nat Metab· May 2019

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Transferrin receptor 1 controls systemic iron homeostasis by fine-tuning hepcidin expression to hepatocellular iron load.
Carine Fillebeen, Edouard Charlebois, John Wagner, Angeliki Katsarou, Jeannie Mui, Prem Ponka

Blood· January 2019

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Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a β-thalassemia mouse model.
Daniel Garcia-Santos, Amel Hamdi, Zuzana Saxova, Carine Fillebeen, Kostas Pantopoulos, Prem Ponka

Blood· January 2018

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The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria.
Aurélie Laroque, Gundula Min-Oo, Mifong Tam, Prem Ponka, Mary M Stevenson

PLoS One· September 2017

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Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells.
Daniel Garcia-Santos, Matthias Schranzhofer, Richard Bergeron, Alex D Sheftel, Prem Ponka

Haematologica· August 2017

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Do Mammalian Cells Really Need to Export and Import Heme?
Prem Ponka, Alex D Sheftel, Ann M English, D Scott Bohle, Daniel Garcia-Santos

Trends Biochem Sci· May 2017

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Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice.
Huihui Li, Tenzin Choesang, Weili Bao, Huiyong Chen, Maria Feola, Prem Ponka

Blood· March 2017

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Erythroid cell mitochondria receive endosomal iron by a "kiss-and-run" mechanism.
Amel Hamdi, Tariq M Roshan, Tanya M Kahawita, Anne B Mason, Alex D Sheftel, Prem Ponka

Biochim Biophys Acta· December 2016

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Response to: Dietary and pharmacological factors affecting iron absorption in mice and man.
Carine Fillebeen, Konstantinos Gkouvatsos, Gabriela Fragoso, Annie Calvé, Daniel Garcia-Santos, Prem Ponka

Haematologica· March 2016

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Mice are poor heme absorbers and do not require intestinal Hmox1 for dietary heme iron assimilation.
Carine Fillebeen, Konstantinos Gkouvatsos, Gabriela Fragoso, Annie Calvé, Daniel Garcia-Santos, Prem Ponka

Haematologica· September 2015

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Thioredoxin-interacting protein regulates the differentiation of murine erythroid precursors.
Jadwiga J Gasiorek, Marc Mikhael, Daniel Garcia-Santos, Simon T Hui, Prem Ponka

Exp Hematol· May 2015

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Heme oxygenase 1 is expressed in murine erythroid cells where it controls the level of regulatory heme.
Daniel Garcia-Santos, Matthias Schranzhofer, Monika Horvathova, Mehrad Mojtahed Jaberi, Jose Artur Bogo Chies, Prem Ponka

Blood· April 2014

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Hepcidin bound to α2-macroglobulin reduces ferroportin-1 expression and enhances its activity at reducing serum iron levels.
Michael Li-Hsuan Huang, Christopher J D Austin, Marie-Agnès Sari, Yohan Suryo Rahmanto, Prem Ponka

J Biol Chem· August 2013

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Nitrogen monoxide inhibits haem synthesis in mouse reticulocytes.
Marc R Mikhael, Tariq Roshan, Shan Soe-Lin, Sameer Apte, Prem Ponka

Biochem J· April 2013

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Snx3 regulates recycling of the transferrin receptor and iron assimilation.
Caiyong Chen, Daniel Garcia-Santos, Yuichi Ishikawa, Alexandra Seguin, Liangtao Li, Prem Ponka

Cell Metab· March 2013

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Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia.
Megan Whitnall, Yohan Suryo Rahmanto, Michael L-H Huang, Federica Saletta, Hiu Chuen Lok, Prem Ponka

Proc Natl Acad Sci U S A· December 2012

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The long history of iron in the Universe and in health and disease.
Alex D Sheftel, Anne B Mason, Prem Ponka

Biochim Biophys Acta· March 2012

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Nitric oxide storage and transport in cells are mediated by glutathione S-transferase P1-1 and multidrug resistance protein 1 via dinitrosyl iron complexes.
Hiu Chuen Lok, Yohan Suryo Rahmanto, Clare L Hawkins, Danuta S Kalinowski, Charles S Morrow, Prem Ponka

J Biol Chem· January 2012

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Iron overload in human disease.
Robert E Fleming, Prem Ponka

N Engl J Med· January 2012

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Antitumor activity of metal-chelating compound Dp44mT is mediated by formation of a redox-active copper complex that accumulates in lysosomes.
David B Lovejoy, Patric J Jansson, Ulf T Brunk, Jacky Wong, Prem Ponka

Cancer Res· September 2011

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Hypoxia. 5. Hypoxia and hematopoiesis.
Donghoon Yoon, Prem Ponka, Josef T Prchal

Am J Physiol Cell Physiol· June 2011

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Antagonistic roles of the ERK and p38 MAPK signalling pathways in globin expression, haem biosynthesis and iron uptake.
Louay Mardini, Jadwiga Gasiorek, Anna Derjuga, Lucie Carrière, Matthias Schranzhofer, Prem Ponka

Biochem J· November 2010

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Ferritin does not donate its iron for haem synthesis in macrophages.
Marc Mikhael, Alex D Sheftel, Prem Ponka

Biochem J· August 2010

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Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol.
Des R Richardson, Darius J R Lane, Erika M Becker, Michael L-H Huang, Megan Whitnall, Prem Ponka

Proc Natl Acad Sci U S A· June 2010

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Molecular basis of hereditary iron homeostasis defects.
Monika Horvathova, Prem Ponka, Vladimir Divoky

Hematology· April 2010

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