Publications by authors named "Alex Lam"

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Staggered immunization with mRNA vaccines encoding SARS-CoV-2 polymerase or spike antigens broadens the T cell epitope repertoire.
Evan R Abt, Alex K Lam, Miyako Noguchi, Khalid Rashid, Jami McLaughlin

Proc Natl Acad Sci U S A· December 2024

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Immunization of Mice with Virus-Like Vesicles of Kaposi Sarcoma-Associated Herpesvirus Reveals a Role for Antibodies Targeting ORF4 in Activating Complement-Mediated Neutralization.
Alex K Lam, Romin Roshan, Wendell Miley, Nazzarena Labo, James Zhen

J Virol· February 2023

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Characterization of T Follicular Helper Cells and T Follicular Regulatory Cells in HIV-Infected and Sero-Negative Individuals.
Bradley Salvatore, Rachel S Resop, Brent R Gordon, Marta Epeldegui, Otoniel Martinez-Maza, Alex Lam

Cells· January 2023

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Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity.
Evan R Abt, Khalid Rashid, Thuc M Le, Suwen Li, Hailey R Lee, Alex K Lam

J Clin Invest· August 2022

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Deletion of immune evasion genes provides an effective vaccine design for tumor-associated herpesviruses.
Gurpreet Brar, Nisar A Farhat, Alisa Sukhina, Alex K Lam, Yong Hoon Kim

NPJ Vaccines· November 2020

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Isolated medial rectus palsy following closed head injury.
David Thean, Alex Lam, Stephen Honeybul

J Clin Neurosci· September 2019

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Human hepatocyte transplantation corrects the inherited metabolic liver disorder arginase deficiency in mice.
Stephanie A K Angarita, Brian Truong, Suhail Khoja, Matthew Nitzahn, Abha K Rajbhandari, Alex K Lam

Mol Genet Metab· June 2018

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Correction: Cardiac ryanodine receptor activation by a high Ca2+ store load is reversed in a reducing cytoplasmic redox environment.
Amy D Hanna, Alex Lam, Chris Thekkedam, Esther M Gallant, Nicole A Beard

J Cell Sci· November 2016

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Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells.
Patrick C Lee, Brian Truong, Agustin Vega-Crespo, W Blake Gilmore, Kip Hermann, Alex K Lam

Mol Ther Nucleic Acids· November 2016

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Adverse effects of doxorubicin and its metabolic product on cardiac RyR2 and SERCA2A.
Amy D Hanna, Alex Lam, Steffi Tham, Angela F Dulhunty, Nicole A Beard

Mol Pharmacol· October 2014

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Cardiac ryanodine receptor activation by a high Ca²⁺ store load is reversed in a reducing cytoplasmic redox environment.
Amy D Hanna, Alex Lam, Chris Thekkedam, Esther M Gallant, Nicole A Beard

J Cell Sci· October 2014

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Blockade of orexin receptors with Almorexant reduces cardiorespiratory responses evoked from the hypothalamus but not baro- or chemoreceptor reflex responses.
Kamon Iigaya, Jouji Horiuchi, Lachlan M McDowall, Alex C B Lam, Yusuf Sediqi

Am J Physiol Regul Integr Comp Physiol· November 2012

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An X-linked channelopathy with cardiomegaly due to a CLIC2 mutation enhancing ryanodine receptor channel activity.
Kyoko Takano, Dan Liu, Patrick Tarpey, Esther Gallant, Alex Lam

Hum Mol Genet· October 2012

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Rapid and robust association mapping of expression quantitative trait loci.
Alex C Lam, Michael Schouten, Yurii S Aulchenko, Chris S Haley, Dirk-Jan de Koning

BMC Proc· December 2009

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A combined strategy for quantitative trait loci detection by genome-wide association.
Alex C Lam, Joseph Powell, Wen-Hua Wei, Dirk-Jan de Koning, Chris S Haley

BMC Proc· February 2009

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Effects of external qigong therapy on osteoarthritis of the knee. A randomized controlled trial.
Kevin W Chen, Adam Perlman, Jason G Liao, Alex Lam, Joy Staller

Clin Rheumatol· December 2008

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Optimal design of genetic studies of gene expression with two-color microarrays in outbred crosses.
Alex C Lam, Jingyuan Fu, Ritsert C Jansen, Chris S Haley, Dirk-Jan de Koning

Genetics· November 2008

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Multiple testing in the genomics era: findings from Genetic Analysis Workshop 15, Group 15.
Lisa J Martin, Jessica G Woo, Christy L Avery, Huann-Sheng Chen, Kari E North, Alex C Lam

Genet Epidemiol· April 2008

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Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.
John A Todd, Neil M Walker, Jason D Cooper, Deborah J Smyth, Kate Downes, Alex A C Lam

Nat Genet· July 2007

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Sequencing and association analysis of the type 1 diabetes-linked region on chromosome 10p12-q11.
Sergey Nejentsev, Luc J Smink, Deborah Smyth, Rebecca Bailey, Christopher E Lowe, Alex Lam

BMC Genet· May 2007

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Interaction analysis of the CBLB and CTLA4 genes in type 1 diabetes.
Felicity Payne, Jason D Cooper, Neil M Walker, Alex C Lam, Luc J Smink

J Leukoc Biol· March 2007

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Mycobacterium marinum arthritis mimicking rheumatoid arthritis.
Alex Lam, Wadie Toma, Naomi Schlesinger

J Rheumatol· April 2006

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Discovery, linkage disequilibrium and association analyses of polymorphisms of the immune complement inhibitor, decay-accelerating factor gene (DAF/CD55) in type 1 diabetes.
Hidenori Taniguchi, Christopher E Lowe, Jason D Cooper, Deborah J Smyth, Rebecca Bailey, Alex C Lam

BMC Genet· April 2006

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Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases.
Deborah J Smyth, Joanna M M Howson, Felicity Payne, Lisa M Maier, Rebecca Bailey, Alex C Lam

BMC Med Genet· March 2006

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Polymorphism discovery and association analyses of the interferon genes in type 1 diabetes.
Gerard A J Morris, Christopher E Lowe, Jason D Cooper, Felicity Payne, Adrian Vella, Alex C Lam

BMC Genet· February 2006

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