Publications by authors named "Alex Lash"

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Analysis of clinical, single cell, and spatial data from the Human Tumor Atlas Network (HTAN) with massively distributed cloud-based queries.
David Gibbs, Dar'ya Pozhidayeva, Yamina Katariya, Boris Aguilar, Kristen Anton, Alex Lash

Res Sq· November 2025

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Analyzing the large and complex SFARI autism cohort data using the Genotypes and Phenotypes in Families (GPF) platform.
Liubomir Chorbadjiev, Murat Cokol, Zohar Weinstein, Kevin Shi, Christopher Fleisch, Alex Lash

Genome Res· October 2025

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Sharing data from the Human Tumor Atlas Network through standards, infrastructure and community engagement.
Ino de Bruijn, Milen Nikolov, Clarisse Lau, Ashley Clayton, David L Gibbs, Alex Lash

Nat Methods· April 2025

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Sharing Data from the Human Tumor Atlas Network through Standards, Infrastructure, and Community Engagement.
Ino de Bruijn, Milen Nikolov, Clarisse Lau, Ashley Clayton, David L Gibbs, Alex Lash

bioRxiv· June 2024

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The Genotype and Phenotypes in Families (GPF) platform manages the large and complex data at SFARI.
Liubomir Chorbadjiev, Murat Cokol, Zohar Weinstein, Kevin Shi, Chris Fleisch, Alex Lash

bioRxiv· February 2024

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Simplifying research access to genomics and health data with Library Cards.
Moran N Cabili, Knox Carey, Stephanie O M Dyke, Anthony J Brookes, Marc Fiume, Alex Lash

Sci Data· March 2018

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Damaging de novo mutations diminish motor skills in children on the autism spectrum.
Andreas Buja, Natalia Volfovsky, Abba M Krieger, Catherine Lord, Alex E Lash

Proc Natl Acad Sci U S A· February 2018

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Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder.
Arjun Krishnan, Ran Zhang, Victoria Yao, Chandra L Theesfeld, Aaron K Wong, Alex Lash

Nat Neurosci· November 2016

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Phase II Study of a Non-Platinum-Containing Doublet of Paclitaxel and Pemetrexed with Bevacizumab as Initial Therapy for Patients with Advanced Lung Adenocarcinomas.
M C Pietanza, Matthew D Hellmann, John J Fiore, Stephanie Smith-Marrone, Ethan M Basch, Alex E Lash

J Thorac Oncol· June 2016

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Robust classification of protein variation using structural modelling and large-scale data integration.
Evan H Baugh, Riley Simmons-Edler, Christian L Müller, Rebecca F Alford, Natalia Volfovsky, Alex E Lash

Nucleic Acids Res· April 2016

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Harnessing technology to improve clinical trials: study of real-time informatics to collect data, toxicities, image response assessments, and patient-reported outcomes in a phase II clinical trial.
M Catherine Pietanza, Ethan M Basch, Alex Lash, Lawrence H Schwartz, Michelle S Ginsberg

J Clin Oncol· June 2013

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Germline mutations in BAP1 predispose to melanocytic tumors.
Thomas Wiesner, Anna C Obenauf, Rajmohan Murali, Isabella Fried, Klaus G Griewank, Alex E Lash

Nat Genet· August 2011

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Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.
Jordi Barretina, Barry S Taylor, Shantanu Banerji, Alexis H Ramos, Mariana Lagos-Quintana, Alex Lash

Nat Genet· August 2010

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Genomic and biological characterization of exon 4 KRAS mutations in human cancer.
Manickam Janakiraman, Efsevia Vakiani, Zhaoshi Zeng, Christine A Pratilas, Barry S Taylor, Alex Lash

Cancer Res· July 2010

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Integrative genomic profiling of human prostate cancer.
Barry S Taylor, Nikolaus Schultz, Haley Hieronymus, Anuradha Gopalan, Yonghong Xiao, Alex E Lash

Cancer Cell· July 2010

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Comprehensive genomic analysis reveals clinically relevant molecular distinctions between thymic carcinomas and thymomas.
Nicolas Girard, Ronglai Shen, Tianhua Guo, Maureen F Zakowski, Adriana Heguy, Alex E Lash

Clin Cancer Res· November 2009

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Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS.
Udayan Guha, Raghothama Chaerkady, Arivusudar Marimuthu, A Scott Patterson, Manoj K Kashyap, Alex E Lash

Proc Natl Acad Sci U S A· September 2008

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Characterizing the cancer genome in lung adenocarcinoma.
Barbara A Weir, Michele S Woo, Gad Getz, Sven Perner, Li Ding, Alex Lash

Nature· December 2007

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Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4.
Jenifer L Marks, Michael D McLellan, Maureen F Zakowski, Alex E Lash, Yumi Kasai

PLoS One· May 2007

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CancerGenes: a gene selection resource for cancer genome projects.
Maureen E Higgins, Martine Claremont, John E Major, Chris Sander, Alex E Lash

Nucleic Acids Res· January 2007

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A FoxO-Smad synexpression group in human keratinocytes.
Roger R Gomis, Claudio Alarcón, Wei He, Qiongqing Wang, Joan Seoane, Alex Lash

Proc Natl Acad Sci U S A· August 2006

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Frequent mutation of the PIK3CA gene in ovarian and breast cancers.
Douglas A Levine, Faina Bogomolniy, Cindy J Yee, Alex Lash, Richard R Barakat

Clin Cancer Res· April 2005

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NCBI GEO: mining millions of expression profiles--database and tools.
Tanya Barrett, Tugba O Suzek, Dennis B Troup, Stephen E Wilhite, Wing-Chi Ngau, Alex E Lash

Nucleic Acids Res· January 2005

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FlyGEM, a full transcriptome array platform for the Drosophila community.
Rick Johnston, Bruce Wang, Rachel Nuttall, Michael Doctolero, Pamela Edwards, Alex Lash

Genome Biol· October 2004

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Database resources of the National Center for Biotechnology.
David L Wheeler, Deanna M Church, Scott Federhen, Alex E Lash, Thomas L Madden

Nucleic Acids Res· January 2003

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