Publications by authors named "Haley Hieronymus"

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Oncogenic ERG Represses PI3K Signaling through Downregulation of IRS2.
Ninghui Mao, Dong Gao, Wenhuo Hu, Sunyana Gadal, Haley Hieronymus

Cancer Res· April 2020

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Aberrant Expression of ERG Promotes Resistance to Combined PI3K and AR Pathway Inhibition through Maintenance of AR Target Genes.
Ninghui Mao, Dong Gao, Wenhuo Hu, Haley Hieronymus, Shangqian Wang

Mol Cancer Ther· September 2019

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Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death.
Haley Hieronymus, Rajmohan Murali, Amy Tin, Kamlesh Yadav, Wassim Abida

Elife· September 2018

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Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors.
Charalambos Kaittanis, Chrysafis Andreou, Haley Hieronymus, Ninghui Mao, Catherine A Foss

J Exp Med· January 2018

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Correction: Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors.
Charalambos Kaittanis, Chrysafis Andreou, Haley Hieronymus, Ninghui Mao, Catherine A Foss

J Exp Med· January 2018

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Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis.
Haley Hieronymus, Phillip J Iaquinta, John Wongvipat, Anuradha Gopalan, Rajmohan Murali

Nat Commun· October 2017

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Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome.
Xian Liu, Tristan R Grogan, Haley Hieronymus, Takao Hashimoto, Jack Mottahedeh

Cell Rep· December 2016

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Identifying actionable targets through integrative analyses of GEM model and human prostate cancer genomic profiling.
Jackie Wanjala, Barry S Taylor, Caren Chapinski, Haley Hieronymus, John Wongvipat

Mol Cancer Ther· January 2015

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Copy number alteration burden predicts prostate cancer relapse.
Haley Hieronymus, Nikolaus Schultz, Anuradha Gopalan, Brett S Carver, Matthew T Chang

Proc Natl Acad Sci U S A· July 2014

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SPOP mutations in prostate cancer across demographically diverse patient cohorts.
Mirjam Blattner, Daniel J Lee, Catherine O'Reilly, Kyung Park, Theresa Y MacDonald, Haley Hieronymus

Neoplasia· January 2014

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Androgen receptor signaling regulates DNA repair in prostate cancers.
William R Polkinghorn, Joel S Parker, Man X Lee, Elizabeth M Kass, Daniel E Spratt, Haley Hieronymus

Cancer Discov· November 2013

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Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screening.
Kimberly Brown Dahlman, Joel S Parker, Tambudzai Shamu, Haley Hieronymus, Caren Chapinski

PLoS One· August 2012

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Traversing the genomic landscape of prostate cancer from diagnosis to death.
Haley Hieronymus, Charles L Sawyers

Nat Genet· May 2012

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A public genome-scale lentiviral expression library of human ORFs.
Xiaoping Yang, Jesse S Boehm, Xinping Yang, Kourosh Salehi-Ashtiani, Tong Hao, Haley Hieronymus

Nat Methods· June 2011

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Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer.
Brett S Carver, Caren Chapinski, John Wongvipat, Haley Hieronymus, Yu Chen

Cancer Cell· May 2011

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MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors.
Nicola J Clegg, Suzana S Couto, John Wongvipat, Haley Hieronymus, Brett S Carver

PLoS One· March 2011

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FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR.
Trever G Bivona, Haley Hieronymus, Joel Parker, Kenneth Chang, Miquel Taron

Nature· March 2011

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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.
Cory M Johannessen, Jesse S Boehm, So Young Kim, Sapana R Thomas, Leslie Wardwell, Haley Hieronymus

Nature· December 2010

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Integrative genomic profiling of human prostate cancer.
Barry S Taylor, Nikolaus Schultz, Haley Hieronymus, Anuradha Gopalan, Yonghong Xiao

Cancer Cell· July 2010

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Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis.
Jennifer C King, Jin Xu, John Wongvipat, Haley Hieronymus, Brett S Carver

Nat Genet· May 2009

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Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy.
Jinyan Du, Paula Bernasconi, Karl R Clauser, D R Mani, Stephen P Finn, Haley Hieronymus

Nat Biotechnol· January 2009

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Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators.
Haley Hieronymus, Justin Lamb, Kenneth N Ross, Xiao P Peng, Cristina Clement

Cancer Cell· October 2006

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The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.
Justin Lamb, Emily D Crawford, David Peck, Joshua W Modell, Irene C Blat, Haley Hieronymus

Science· September 2006

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A systems view of mRNP biology.
Haley Hieronymus, Pamela A Silver

Genes Dev· December 2004

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Genome-wide mRNA surveillance is coupled to mRNA export.
Haley Hieronymus, Michael C Yu, Pamela A Silver

Genes Dev· November 2004

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