Publications by authors named "Alex Odermatt"

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Estimates of skin and blood concentrations of UV-filters: Insights from in vitro skin experiments.
Hélène P De Luca, Stéphanie Boudon, Alex Odermatt, Linda Schenk, Nancy B Hopf

Regul Toxicol Pharmacol· December 2025

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Optimizing efficacy and safety of T cell bispecific antibodies: the interdependence of CD3 and tumor antigen binder affinities in FOLR1 and CEACAM5 2 + 1 TCBs.
Omar Abdelmotaleb, Anneliese Schneider, Inja Waldhauer, Johannes Sam, Thomas Hofer, Alex Odermatt

MAbs· December 2025

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Hormonal changes in professional printers exposed to phthalates suggesting potential disturbances of the hypothalamic-pituitary-gonadal axis.
Tiberiu M Nita, Sonja A Wrobel, David Vernez, Holger M Koch, Pascal Wild, Alex Odermatt

Environ Res· December 2025

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SACF and GILA assays on AML12 cells show limited predictive value for mouse liver genotoxicity.
Erica Coratella, Rebecca Bohnert, Benoit Fischer, Myriam Lemmens, Tara Alpert, Alex Odermatt

Toxicol Appl Pharmacol· November 2025

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Multidisciplinary Preclinical Investigations on Ferrocenyl, Ruthenocenyl, and Benzyl Derivatives of Niridazole as New Drug Candidates against Schistosomiasis.
Tanja Karpstein, Shuai Zhong, Sarah Keller, Philipp Späne, Cécile Häberli, Alex Odermatt

ChemMedChem· November 2025

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ApoE4 disrupts intracellular trafficking and iron homeostasis in a reproducible iPSC-based model of human brain endothelial cells.
Luisa Bell, Shane Clerkin, Sila Rizalar, Antoine Rizkallah, Nadine Stokar-Regenscheit, Alex Odermatt

Stem Cell Reports· September 2025

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Alterations in glucocorticoid homeostasis following sleeve gastrectomy.
Seraina O Moser, Andrei Moscalu, Cullen F Roberts, Denise V Winter, Friedrich L Joos, Alex Odermatt

bioRxiv· September 2025

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Synthesis and Multidisciplinary Preclinical Investigations of Ferrocenyl, Ruthenocenyl, and Benzyl Derivatives of Thiabendazole as New Drug Candidates against Soil-Transmitted Helminth Infections.
Tanja Karpstein, Apollonia Kalamatianou, Sarah Keller, Philipp Späne, Cécile Häberli, Alex Odermatt

ACS Infect Dis· July 2025

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Elucidation of B-cell specific drug immunogenicity liabilities via a novel assay.
Cary M Looney, Axel Ducret, Guido Steiner, Karen Dernick, Katharina Hartman, Alex Odermatt

Front Immunol· June 2025

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The long way from raw data to NAM-based information: Overview on data layers and processing steps.
Jonathan Blum, Markus Brüll, Jan G Hengstler, Daniel R Dietrich, Andreas J Gruber, Alex Odermatt

ALTEX· May 2025

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Discovery of non-steroidal aldo-keto reductase 1D1 inhibitors through automated screening and in vitro evaluation.
Jacek Kȩdzierski, Rianne E van Diest, Julien A Allard, Alex Odermatt, Martin Smieško

Toxicol Lett· April 2025

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A BioID-based approach uncovers the interactome of hexose-6-phosphate dehydrogenase in breast cancer cells and identifies anterior gradient protein 2 as an interacting partner.
Gabriele Sakalauskaite, Michael Weingartner, Sophie Ebert, Gina Boot, Thomas Bock, Alex Odermatt

Cell Biosci· April 2025

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Disruption of serotonin homeostasis in intestinal organoids provides insights into drug-induced gastrointestinal toxicity.
Georgia M Rouseti, Audrey Fischer, Nicole Rathfelder, Karen Grimes, Annick Waldt, Alex Odermatt

Toxicology· February 2025

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Advanced tissue technologies of blood-brain barrier organoids as high throughput toxicity readouts in drug development.
Luisa Bell, Claire Simonneau, Chiara Zanini, Elena Kassianidou, Christelle Zundel, Alex Odermatt

Heliyon· January 2025

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Potential antiandrogenic effects of parabens and benzophenone-type UV-filters by inhibition of 3α-hydroxysteroid dehydrogenases.
Manuel Kley, Simon Stücheli, Pamela Ruffiner, Veronika Temml, Stéphanie Boudon, Alex Odermatt

Toxicology· December 2024

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Assessment of the potential risk of oteseconazole and two other tetrazole antifungals to inhibit adrenal steroidogenesis and peripheral metabolism of corticosteroids.
Marie-Christin Jäger, Víctor González-Ruiz, Friedrich L Joos, Denise V Winter, Julien Boccard, Alex Odermatt

Front Pharmacol· August 2024

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Metabolic outcomes in obese mice undergoing one-anastomosis gastric bypass (OAGB) with a long or a short biliopancreatic limb.
Ioannis I Lazaridis, Angela J T Bosch, Lena Keller, Andy J Y Low, Jeanne Tamarelle, Alex Odermatt

Am J Physiol Endocrinol Metab· June 2024

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In silico and in vitro assessment of drugs potentially causing adverse effects by inhibiting CYP17A1.
Jacek Kędzierski, Marie-Christin Jäger, Sadaf Naeem, Alex Odermatt, Martin Smieško

Toxicol Appl Pharmacol· May 2024

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Identification of a human blood biomarker of pharmacological 11β-hydroxysteroid dehydrogenase 1 inhibition.
Cristina Gómez, Zerin Alimajstorovic, Nantia Othonos, Denise V Winter, Sarah White, Alex Odermatt

Br J Pharmacol· March 2024

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Mechanisms of hepatocellular toxicity associated with the components of St. John's Wort extract hypericin and hyperforin in HepG2 and HepaRG cells.
Vanessa Fabienne Abegg, Miljenko Valentin Panajatovic, Riccardo Vincenzo Mancuso, Julien Arthur Allard, Urs Duthaler, Alex Odermatt

Toxicol Lett· March 2024

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A battery of in silico models application for pesticides exerting reproductive health effects: Assessment of performance and prioritization of mechanistic studies.
Serhii Kolesnyk, Mykola Prodanchuk, Petro Zhminko, Yana Kolianchuk, Nataliia Bubalo, Alex Odermatt

Toxicol In Vitro· December 2023

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In vitro methods to assess 11β-hydroxysteroid dehydrogenase type 1 activity.
Manuel Kley, Seraina O Moser, Denise V Winter, Alex Odermatt

Methods Enzymol· November 2023

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In vitro methods to assess 11β-hydroxysteroid dehydrogenase type 2 activity.
Manuel Kley, Seraina O Moser, Denise V Winter, Alex Odermatt

Methods Enzymol· November 2023

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Editorial: Steroid hormone receptors in cardiometabolic disease.
Julie Goodwin, Alex Odermatt, Ruth Morgan, Mark Nixon

Front Endocrinol (Lausanne)· August 2023

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Characterization of the interferences of systemic azole antifungal drugs with adrenal steroid biosynthesis using H295R cells and enzyme activity assays.
Marie-Christin Jäger, Friedrich L Joos, Denise V Winter, Alex Odermatt

Curr Res Toxicol· August 2023

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