Publications by authors named "Andreas J Gruber"

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Replication-associated mechanisms contribute to an increased CpG > TpG mutation burden in mismatch repair-deficient cancers.
Joseph C Ward, Ignacio Soriano, Steve Thorn, Juan Fernández-Tajes, Kitty Sherwood, Andreas J Gruber

Genome Med· August 2025

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The long way from raw data to NAM-based information: Overview on data layers and processing steps.
Jonathan Blum, Markus Brüll, Jan G Hengstler, Daniel R Dietrich, Andreas J Gruber

ALTEX· May 2025

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Genomic landscape of diffuse glioma revealed by whole genome sequencing.
Ben Kinnersley, Josephine Jung, Alex J Cornish, Daniel Chubb, Ross Laxton, Andreas J Gruber

Nat Commun· May 2025

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Causes of evolutionary divergence in prostate cancer.
Emre Esentürk, Atef Sahli, Valeriia Haberland, Aleksandra Ziuboniewicz, Christopher Wirth, Andreas J Gruber

ArXiv· March 2025

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Genomic landscape of adult testicular germ cell tumours in the 100,000 Genomes Project.
Máire Ní Leathlobhair, Anna Frangou, Ben Kinnersley, Alex J Cornish, Daniel Chubb, Andreas J Gruber

Nat Commun· October 2024

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Analysis of 10,478 cancer genomes identifies candidate driver genes and opportunities for precision oncology.
Ben Kinnersley, Amit Sud, Andrew Everall, Alex J Cornish, Daniel Chubb, Andreas J Gruber

Nat Genet· September 2024

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The genomic landscape of 2,023 colorectal cancers.
Alex J Cornish, Andreas J Gruber, Ben Kinnersley, Daniel Chubb, Anna Frangou

Nature· September 2024

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Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma.
Richard Culliford, Samuel E D Lawrence, Charlie Mills, Zayd Tippu, Daniel Chubb, Andreas J Gruber

Nat Commun· July 2024

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MAPP unravels frequent co-regulation of splicing and polyadenylation by RNA-binding proteins and their dysregulation in cancer.
Maciej Bak, Erik van Nimwegen, Ian U Kouzel, Tamer Gur, Ralf Schmidt, Andreas J Gruber

Nat Commun· May 2024

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Genomic evolution shapes prostate cancer disease type.
Dan J Woodcock, Atef Sahli, Ruxandra Teslo, Vinayak Bhandari, Andreas J Gruber

Cell Genom· March 2024

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scTEA-db: a comprehensive database of novel terminal exon isoforms identified from human single cell transcriptomes.
Miguel Barquin, Ian U Kouzel, Beat Ehrmann, Michael Basler, Andreas J Gruber

Nucleic Acids Res· January 2024

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Uncovering novel mutational signatures by extraction with SigProfilerExtractor.
S M Ashiqul Islam, Marcos Díaz-Gay, Yang Wu, Mark Barnes, Raviteja Vangara, Andreas J Gruber

Cell Genom· November 2022

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Investigating the Human Host-ssRNA Virus Interaction Landscape Using the SMEAGOL Toolbox.
Avantika Lal, Mariana Galvao Ferrarini, Andreas J Gruber

Viruses· June 2022

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Germline MBD4 deficiency causes a multi-tumor predisposition syndrome.
Claire Palles, Hannah D West, Edward Chew, Sara Galavotti, Christoffer Flensburg, Andreas J Gruber

Am J Hum Genet· May 2022

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The International Virus Bioinformatics Meeting 2022.
Franziska Hufsky, Denis Beslic, Dimitri Boeckaerts, Sebastian Duchene, Enrique González-Tortuero, Andreas J Gruber

Viruses· May 2022

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Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes.
Naser Ansari-Pour, Yonglan Zheng, Toshio F Yoshimatsu, Ayodele Sanni, Mustapha Ajani, Andreas J Gruber

Nat Commun· November 2021

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Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis.
Mariana G Ferrarini, Avantika Lal, Rita Rebollo, Andreas J Gruber, Andrea Guarracino

Commun Biol· May 2021

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PolyASite 2.0: a consolidated atlas of polyadenylation sites from 3' end sequencing.
Christina J Herrmann, Ralf Schmidt, Alexander Kanitz, Panu Artimo, Andreas J Gruber

Nucleic Acids Res· January 2020

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Reply to 'A different perspective on alternative cleavage and polyadenylation'.
Andreas J Gruber, Mihaela Zavolan

Nat Rev Genet· January 2020

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Alternative cleavage and polyadenylation in health and disease.
Andreas J Gruber, Mihaela Zavolan

Nat Rev Genet· October 2019

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Terminal exon characterization with TECtool reveals an abundance of cell-specific isoforms.
Andreas J Gruber, Foivos Gypas, Andrea Riba, Ralf Schmidt, Mihaela Zavolan

Nat Methods· October 2018

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Single-cell mRNA profiling reveals the hierarchical response of miRNA targets to miRNA induction.
Andrzej J Rzepiela, Souvik Ghosh, Jeremie Breda, Arnau Vina-Vilaseca, Afzal P Syed, Andreas J Gruber

Mol Syst Biol· August 2018

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Discovery of physiological and cancer-related regulators of 3' UTR processing with KAPAC.
Andreas J Gruber, Ralf Schmidt, Souvik Ghosh, Georges Martin, Andreas R Gruber

Genome Biol· March 2018

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3' End Sequencing Library Preparation with A-seq2.
Georges Martin, Ralf Schmidt, Andreas J Gruber, Souvik Ghosh, Walter Keller

J Vis Exp· October 2017

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TFAP2A is a component of the ZEB1/2 network that regulates TGFB1-induced epithelial to mesenchymal transition.
Yoana Dimitrova, Andreas J Gruber, Nitish Mittal, Souvik Ghosh, Beatrice Dimitriades

Biol Direct· April 2017

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