Publications by authors named "Alex Phillipou"

Claim this Profile
B
BET Isoform Selectivity through Diverse Linkers for Bivalent Inhibitors: GSK785, a BRD2/4-Selective Bivalent BET Inhibitor.
Francesco Rianjongdee, Stephen J Atkinson, Paul Bamborough, Heather A Barnett, Kallie Friston, Alex Phillipou

J Med Chem· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Optimization of Potent and Selective Cyclohexyl Acid ERAP1 Inhibitors Using Structure- and Property-Based Drug Design.
Ross P Hryczanek, Andrew S Hackett, Paul Rowland, Chun-Wa Chung, Máire A Convery, Alex Phillipou

ACS Med Chem Lett· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-Guided Design of a Domain-Selective Bromodomain and Extra Terminal N-Terminal Bromodomain Chemical Probe.
Erin Bradley, Lucia Fusani, Chun-Wa Chung, Peter D Craggs, Emmanuel H Demont, Alex Phillipou

J Med Chem· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design and Characterization of 1,3-Dihydro-2-benzo[]azepin-2-ones as Rule-of-5 Compliant Bivalent BET Inhibitors.
Paul Bamborough, Chun-Wa Chung, Nicole C Goodwin, Darren J Mitchell, Christopher E Neipp, Alex Phillipou

ACS Med Chem Lett· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Photoaffinity labelling displacement assay using multiple recombinant protein domains.
David J Fallon, Alex Phillipou, Christopher J Schofield, David House, Nicholas C O Tomkinson

Biochem J· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
One-Step Synthesis of Photoaffinity Probes for Live-Cell MS-Based Proteomics.
David J Fallon, Stephanie Lehmann, Chun-Wa Chung, Alex Phillipou, Christian Eberl

Chemistry· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of a Highly Selective BET BD2 Inhibitor from a DNA-Encoded Library Technology Screening Hit.
Francesco Rianjongdee, Stephen J Atkinson, Chun-Wa Chung, Paola Grandi, James R J Gray, Alex Phillipou

J Med Chem· August 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fragment-based Scaffold Hopping: Identification of Potent, Selective, and Highly Soluble Bromo and Extra Terminal Domain (BET) Second Bromodomain (BD2) Inhibitors.
Jonathan T Seal, Stephen J Atkinson, Paul Bamborough, Anna Bassil, Chun-Wa Chung, Alex Phillipou

J Med Chem· August 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Optimization of Naphthyridones into Selective TATA-Binding Protein Associated Factor 1 (TAF1) Bromodomain Inhibitors.
Michael A Clegg, Natalie H Theodoulou, Paul Bamborough, Chun-Wa Chung, Peter D Craggs, Alex Phillipou

ACS Med Chem Lett· August 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
GSK789: A Selective Inhibitor of the First Bromodomains (BD1) of the Bromo and Extra Terminal Domain (BET) Proteins.
Robert J Watson, Paul Bamborough, Heather Barnett, Chun-Wa Chung, Rob Davis, Alex Phillipou

J Med Chem· September 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting the Regulatory Site of ER Aminopeptidase 1 Leads to the Discovery of a Natural Product Modulator of Antigen Presentation.
John Liddle, Jonathan P Hutchinson, Semra Kitchen, Paul Rowland, Margarete Neu, Alex Phillipou

J Med Chem· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis