Publications by authors named "Anna Bassil"

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Phase 1 and preclinical profiling of ESM-HDAC391, a myeloid-targeted histone deacetylase inhibitor, shows enhanced pharmacology and monocytopaenia.
Rebecca C Furze, Judit Molnar, Nigel J Parr, Faiz Ahmad, Yvette Henry, Anna K Bassil

Br J Clin Pharmacol· December 2022

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Identification of a Series of -Methylpyridine-2-carboxamides as Potent and Selective Inhibitors of the Second Bromodomain (BD2) of the Bromo and Extra Terminal Domain (BET) Proteins.
Lee A Harrison, Stephen J Atkinson, Anna Bassil, Chun-Wa Chung, Paola Grandi

J Med Chem· August 2021

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Fragment-based Scaffold Hopping: Identification of Potent, Selective, and Highly Soluble Bromo and Extra Terminal Domain (BET) Second Bromodomain (BD2) Inhibitors.
Jonathan T Seal, Stephen J Atkinson, Paul Bamborough, Anna Bassil, Chun-Wa Chung

J Med Chem· August 2021

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Template-Hopping Approach Leads to Potent, Selective, and Highly Soluble Bromo and Extraterminal Domain (BET) Second Bromodomain (BD2) Inhibitors.
Helen E Aylott, Stephen J Atkinson, Paul Bamborough, Anna Bassil, Chun-Wa Chung

J Med Chem· March 2021

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Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.
Omer Gilan, Inmaculada Rioja, Kathy Knezevic, Matthew J Bell, Miriam M Yeung, Anna K Bassil

Science· April 2020

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Signaling function of PRC2 is essential for TCR-driven T cell responses.
Marc-Werner Dobenecker, Joon Seok Park, Jonas Marcello, Michael T McCabe, Richard Gregory, Anna K Bassil

J Exp Med· April 2018

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Potent antimyeloma activity of the novel bromodomain inhibitors I-BET151 and I-BET762.
Aristeidis Chaidos, Valentina Caputo, Katerina Gouvedenou, Binbin Liu, Ilaria Marigo, Anna K Bassil

Blood· January 2014

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UDP-glucose modulates gastric function through P2Y14 receptor-dependent and -independent mechanisms.
Anna K Bassil, Sophie Bourdu, Karen A Townson, Alan Wheeldon, Emma M Jarvie

Am J Physiol Gastrointest Liver Physiol· April 2009

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Inhibition by tianeptine of neuronally mediated contractions in the rat isolated gastrointestinal tract.
Victoria N Bolton, Anna K Bassil, Kevin Lee, Gareth J Sanger

Pharmacol Res· May 2008

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Demonstration of functional neuronal beta3-adrenoceptors within the enteric nervous system.
Selim Cellek, Ramkumar Thangiah, Anna K Bassil, Colin A Campbell, Karen M Gray

Gastroenterology· July 2007

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The prokinetic-like activity of ghrelin in rat isolated stomach is mediated via cholinergic and tachykininergic motor neurones.
Anna K Bassil, Narinder B Dass, Gareth J Sanger

Eur J Pharmacol· August 2006

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Prokineticin-2, motilin, ghrelin and metoclopramide: prokinetic utility in mouse stomach and colon.
Anna K Bassil, Narinder B Dass, Charles D Murray, Alison Muir, Gareth J Sanger

Eur J Pharmacol· November 2005

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