Publications by authors named "Alexander A Vinks"

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Building a Beta-Lactam Model-Informed Precision Dosing Service in a Quaternary Care Children's Hospital.
Sonya Tang Girdwood, Ronaldo Morales Junior, Erin Schuler, Peter Tang, Emily Diseroad, Alexander A Vinks

Clin Transl Sci· December 2025

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The Coming of Age of Model-Informed Precision Therapeutics for Children.
Alexander A Vinks

J Pediatr Pharmacol Ther· December 2025

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Microsensor Array for the Electrochemical Analysis of Hydroxyurea in Blood Samples of Children Affected by Sickle Cell Anemia.
Rajendra P Shukla, Matan Aroosh, Remi Cazelles, Russell E Ware, Alexander A Vinks

Anal Chem· November 2025

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Hydroxyurea pharmacokinetics in children with sickle cell anemia across different global populations.
Alexandra Power-Hays, Kathryn E McElhinney, Thomas N Williams, George Mochamah, Peter Olupot-Olupot, Alexander A Vinks

Blood Adv· September 2025

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Belatacept Pharmacokinetic Analysis of Belatacept Early Steroid Withdrawal Trial (BEST) to Clinical Outcomes and Compared With Reported BENEFIT and BENEFIT-EXT Pharmacokinetic Analysis.
Alexandra Pyatt, Melissa McGowan, Ryota Tanaka, Bradley Miyagawa, Tomoyuki Mizuno, Alexander A Vinks

Clin Transplant· August 2025

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The feasibility of pharmacokinetic-based dosing of hydroxyurea for children with sickle cell anaemia in Uganda: Baseline results of the alternative dosing and prevention of transfusions trial.
Alexandra Power-Hays, Ruth Namazzi, Min Dong, Caroline Kazinga, Charles Kato, Alexander A Vinks

Br J Clin Pharmacol· June 2025

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The feasibility of pharmacokinetic-based dosing of hydroxyurea for children with sickle cell anaemia in Uganda: Baseline results of the alternative dosing and prevention of transfusions trial.
Alexandra Power-Hays, Ruth Namazzi, Min Dong, Caroline Kazinga, Charles Kato, Alexander A Vinks

Br J Clin Pharmacol· April 2025

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Acute kidney injury is associated with abnormal cefepime exposure among critically ill children and young adults.
Kathryn Pavia, Sonya Tang Girdwood, Kelli Paice, Min Dong, Tomoyuki Mizuno, Alexander A Vinks

Pediatr Nephrol· February 2025

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Integrating early response biomarkers in pharmacokinetic models: A novel method to individualize the initial infliximab dose in patients with Crohn's disease.
Abigail Samuels, Kei Irie, Tomoyuki Mizuno, Jack Reifenberg, Nieko Punt, Alexander A Vinks

Clin Transl Sci· February 2025

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Pharmacokinetic Factors Associated With Early Meropenem Target Attainment in Pediatric Severe Sepsis.
Kelli Paice, Sonya Tang Girdwood, Tomoyuki Mizuno, Kathryn Pavia, Nieko Punt, Alexander A Vinks

Pediatr Crit Care Med· December 2024

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Rationale, Development, and Validation of HdxSim, a Clinical Decision Support Tool for Model-Informed Precision Dosing of Hydroxyurea for Children with Sickle Cell Anemia.
Alexandra Power-Hays, Min Dong, Nieko Punt, Tomoyuki Mizuno, Luke R Smart, Alexander A Vinks

Clin Pharmacol Ther· September 2024

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A pharmacokinetic-pharmacodynamic analysis of l-glutamine for the treatment of sickle cell disease: Implications for understanding the mechanism of action and evaluating response to therapy.
Alina Sadaf, Min Dong, Amanda Pfeiffer, Jennifer Korpik, Theodosia A Kalfa, Alexander A Vinks

Br J Haematol· September 2024

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Belatacept Removal by Plasmapheresis: Dose Adjustments and Clinical Recommendations.
Nicole K Wilson, Simon Tremblay, Adele R Shields, E Steve Woodle, Rita R Alloway, Alexander A Vinks

Transplant Direct· August 2024

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Development and Verification of a Full Physiologically Based Pharmacokinetic Model for Sublingual Buprenorphine in Healthy Adult Volunteers that Accounts for Nonlinear Bioavailability.
Matthijs W van Hoogdalem, Ryota Tanaka, Trevor N Johnson, Alexander A Vinks, Tomoyuki Mizuno

Drug Metab Dispos· July 2024

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Preventative treatment of tuberous sclerosis complex with sirolimus: Phase I safety and efficacy results.
Jamie K Capal, David M Ritter, David Neal Franz, Molly Griffith, Kristn Currans, Alexander A Vinks

Ann Child Neurol Soc· June 2024

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Ceftriaxone Pharmacokinetics and Pharmacodynamic Target Attainment for Three Pediatric Patients Receiving Continuous Kidney Replacement Therapy.
H Rhodes Hambrick, Francisco Cervantes, Min Dong, Peter Tang, Trent Arbough, Alexander A Vinks

J Pediatr Pharmacol Ther· April 2024

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Piperacillin pharmacokinetics and pharmacodynamics in paediatric patients who received high frequency intra-operative piperacillin/tazobactam dosing.
Carter McIntire, Julie Luna Torres, Peter Tang, Alexander A Vinks, Jennifer Kaplan

Int J Antimicrob Agents· March 2024

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A Population Pharmacokinetic Analysis of L-Glutamine Exposure in Patients with Sickle Cell Disease: Evaluation of Dose and Food Effects.
Alina Sadaf, Min Dong, Amanda Pfeiffer, Teresa Latham, Theodosia Kalfa, Alexander A Vinks

Clin Pharmacokinet· March 2024

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Precise infliximab exposure and pharmacodynamic control to achieve deep remission in paediatric Crohn's disease (REMODEL-CD): study protocol for a multicentre, open-label, pragmatic clinical trial in the USA.
Phillip Paul Minar, Ruben J Colman, Nanhua Zhang, Tomoyuki Mizuno, Alexander A Vinks

BMJ Open· March 2024

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Forecasting Fetal Buprenorphine Exposure through Maternal-Fetal Physiologically Based Pharmacokinetic Modeling.
Matthijs W van Hoogdalem, Ryota Tanaka, Khaled Abduljalil, Trevor N Johnson, Scott L Wexelblatt, Alexander A Vinks

Pharmaceutics· March 2024

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Ceftriaxone Pharmacokinetics and Pharmacodynamics in 2 Pediatric Patients on Extracorporeal Membrane Oxygenation Therapy.
Francisco C Cervantes, Tomoyuki Mizuno, Min Dong, Peter Tang, Trent Arbough, Alexander A Vinks

Ther Drug Monit· December 2023

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Tutorial on model selection and validation of model input into precision dosing software for model-informed precision dosing.
Zachary L Taylor, Ethan A Poweleit, Kelli Paice, Katherine M Somers, Kathryn Pavia, Alexander A Vinks

CPT Pharmacometrics Syst Pharmacol· December 2023

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Adopting Model-Informed Precision-Dosing for Eculizumab in Transplant Associated-Thrombotic Microangiopathy to Gene Therapies.
Sonata Jodele, Kana Mizuno, Anthony Sabulski, Alexander A Vinks

Clin Pharmacol Ther· September 2023

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Cefepime pharmacokinetics in critically ill children and young adults undergoing continuous kidney replacement therapy.
Kathryn Pavia, H Rhodes Hambrick, Kelli Paice, Peter Tang, Nieko Punt, Alexander A Vinks

J Antimicrob Chemother· September 2023

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Novel Therapeutic Modalities: The Future is Now.
Yewon Choi, Alexander A Vinks, Piet H van der Graaf

Clin Pharmacol Ther· September 2023

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