Publications by authors named "Alexander Buell"

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Thermodynamic stability modulates chaperone-mediated disaggregation of α-synuclein fibrils.
Celia Fricke, Antonin Kunka, Rasmus K Norrild, Shuangyan Wang, Thi Lieu Dang, Alexander K Buell

Chem Sci· January 2026

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Structural polymorphism of α-synuclein fibrils alters the pathway of Hsc70-mediated disaggregation.
Svenja Jäger, Jessica Tittelmeier, Thi Lieu Dang, Tracy Bellande, Virginie Redeker, Alexander K Buell

EMBO J· November 2025

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A QCM-D-based continuous assay for the study of the enzymatic degradation of insoluble calcium-polygalacturonate.
Nathan Cannac, Sune Fjermedal, Jacob Aunstrup Larsen, Alexander K Buell, Anne S Meyer

Carbohydr Polym· September 2025

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Tracking reduction-induced molecular changes in pathological free light chains by SV-AUC.
Florian T Tucholski, Rebecca Sternke-Hoffmann, Thomas Pauly, Rasmus K Norrild, Amelie Boquoi, Alexander K Buell

Eur Biophys J· August 2025

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Global kinetic model of lipid-induced -synuclein aggregation and its inhibition by small molecules.
Alisdair Stevenson, Roxine Staats, Alexander J Dear, David Voderholzer, Jesper E Dreier, Alexander K Buell

Proc Natl Acad Sci U S A· July 2025

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Probing the effect of the disordered flank regions on amyloid fibril growth and proliferation.
Jacob Aunstrup Larsen, Juami H M van Gils, Soumik Ray, Marcel Dickmanns, Shuangyan Wang, Alexander K Buell

RSC Adv· June 2025

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On the thermal and chemical stability of DNAJB6b and its globular domains.
Celia Fricke, Jelica Milošević, Andreas Carlsson, Lars Boyens-Thiele, Marija Dubackic, Alexander K Buell

Biophys Chem· May 2025

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Semi-rational evolution of a recombinant DNA polymerase for modified nucleotide incorporation efficiency.
Lili Zhai, Zi Wang, Fen Liu, Chongjun Xu, Jingjing Wang, Alexander K Buell

PLoS One· May 2025

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Induction and Manipulation of Biomolecular Condensates Through Spatially Heterogeneous Solution Conditions.
Alexander K Buell

Chembiochem· May 2025

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The mechanism of amyloid fibril growth from Φ-value analysis.
Jacob Aunstrup Larsen, Abigail Barclay, Nicola Vettore, Louise K Klausen, Lena N Mangels, Alexander K Buell

Nat Chem· March 2025

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The Amplification of Alpha-Synuclein Amyloid Fibrils is Suppressed under Fully Quiescent Conditions.
Azad Farzadfard, Thomas O Mason, Antonin Kunka, Hossein Mohammad-Beigi, Kaare Bjerregaard-Andersen, Alexander K Buell

Angew Chem Int Ed Engl· February 2025

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Engineering of pH-dependent antigen binding properties for toxin-targeting IgG1 antibodies using light-chain shuffling.
Tulika Tulika, Fulgencio Ruso-Julve, Shirin Ahmadi, Anne Ljungars, Esperanza Rivera-de-Torre, Alexander K Buell

Structure· September 2024

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Amyloid formation and depolymerization of tumor suppressor p16 are regulated by a thiol-dependent redox mechanism.
Sarah G Heath, Shelby G Gray, Emilie M Hamzah, Karina M O'Connor, Stephanie M Bozonet, Alexander K Buell

Nat Commun· July 2024

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Taylor Dispersion-Induced Phase Separation for the Efficient Characterisation of Protein Condensate Formation.
Rasmus K Norrild, Thomas O Mason, Lars Boyens-Thiele, Soumik Ray, Joachim B Mortensen, Alexander K Buell

Angew Chem Int Ed Engl· June 2024

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Degree of hydrolysis is a poor predictor of the sensitizing capacity of whey- and casein-based hydrolysates in a Brown Norway rat model of cow's milk allergy.
Katrine Lindholm Bøgh, Ditte Møller Nielsen, Hossein Mohammad-Beigi, Heidi Frahm Christoffersen, Lotte Neergaard Jacobsen, Alexander Kai Buell

Food Res Int· April 2024

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Structural characterisation of α-synuclein-membrane interactions and the resulting aggregation using small angle scattering.
Céline Galvagnion, Abigail Barclay, Katarzyna Makasewicz, Frederik Ravnkilde Marlet, Martine Moulin, Alexander K Buell

Phys Chem Chem Phys· April 2024

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Emerging experimental methods to study the thermodynamics of biomolecular condensate formation.
Soumik Ray, Alexander K Buell

J Chem Phys· March 2024

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Thermodynamic characterization of amyloid polymorphism by microfluidic transient incomplete separation.
Azad Farzadfard, Antonin Kunka, Thomas Oliver Mason, Jacob Aunstrup Larsen, Rasmus Krogh Norrild, Alexander K Buell

Chem Sci· February 2024

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Mass photometric detection and quantification of nanoscale α-synuclein phase separation.
Soumik Ray, Thomas O Mason, Lars Boyens-Thiele, Azad Farzadfard, Jacob Aunstrup Larsen, Alexander K Buell

Nat Chem· September 2023

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Pyroglutamate-modified amyloid β(3-42) monomer has more β-sheet content than the amyloid β(1-42) monomer.
Soumav Nath, Alexander K Buell, Bogdan Barz

Phys Chem Chem Phys· June 2023

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Generation of robust bispecific antibodies through fusion of single-domain antibodies on IgG scaffolds: a comprehensive comparison of formats.
Andreas V Madsen, Peter Kristensen, Alexander K Buell, Steffen Goletz

MAbs· March 2023

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Structural polymorphism of the low-complexity C-terminal domain of TDP-43 amyloid aggregates revealed by solid-state NMR.
Jayakrishna Shenoy, Alons Lends, Mélanie Berbon, Muhammed Bilal, Nadia El Mammeri, Alexander K Buell

Front Mol Biosci· March 2023

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Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chains.
Rebecca Sternke-Hoffmann, Thomas Pauly, Rasmus K Norrild, Jan Hansen, Florian Tucholski, Alexander K Buell

BMC Biol· February 2023

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Stability matters, too - the thermodynamics of amyloid fibril formation.
Alexander K Buell

Chem Sci· September 2022

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The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors.
Jasmin Bartl, Marco Zanini, Flavia Bernardi, Antoine Forget, Lena Blümel, Alexander Buell

Nat Commun· July 2022

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