Publications by authors named "Alexander D Blanchette"

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Probabilistic risk assessment of residential exposure to electric arc furnace steel slag using Bayesian model of relative bioavailability and PBPK modeling of manganese.
Liz Mittal, Camarie S Perry, Alexander D Blanchette, Deborah M Proctor

Risk Anal· September 2024

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Use of physiologically based pharmacokinetic modeling to support development of an acute (24-hour) health-based inhalation guideline for manganese.
Camarie S Perry, Alexander D Blanchette, Stephanie N Vivanco, Ann H Verwiel, Deborah M Proctor

Regul Toxicol Pharmacol· December 2023

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Assessment of the in vivo genotoxic potential of three smoke flavoring primary product mixtures.
Chad M Thompson, Gregory Brorby, Zena Keig-Shevlin, Robert Smith, Allison Franzen, Alexander D Blanchette

Environ Mol Mutagen· December 2023

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Manganese relative oral bioavailability in electric arc furnace steel slag is influenced by high iron content and low bioaccessibility.
Deborah M Proctor, Stephanie N Vivanco, Alexander D Blanchette

Toxicol Sci· May 2023

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A tiered approach to population-based in vitro testing for cardiotoxicity: Balancing estimates of potency and variability.
Alexander D Blanchette, Sarah D Burnett, Ivan Rusyn, Weihsueh A Chiu

J Pharmacol Toxicol Methods· March 2022

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Cardiotoxicity Hazard and Risk Characterization of ToxCast Chemicals Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Multiple Donors.
Sarah D Burnett, Alexander D Blanchette, Weihsueh A Chiu, Ivan Rusyn

Chem Res Toxicol· September 2021

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Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes as an in vitro model in toxicology: strengths and weaknesses for hazard identification and risk characterization.
Sarah D Burnett, Alexander D Blanchette, Weihsueh A Chiu, Ivan Rusyn

Expert Opin Drug Metab Toxicol· August 2021

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Relationships between constituents of energy drinks and beating parameters in human induced pluripotent stem cell (iPSC)-Derived cardiomyocytes.
Yu-Syuan Luo, Zunwei Chen, Alexander D Blanchette, Yi-Hui Zhou, Fred A Wright

Food Chem Toxicol· March 2021

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A Bayesian Method for Population-wide Cardiotoxicity Hazard and Risk Characterization Using an In Vitro Human Model.
Alexander D Blanchette, Sarah D Burnett, Fabian A Grimm, Ivan Rusyn, Weihsueh A Chiu

Toxicol Sci· December 2020

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Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes.
Sarah D Burnett, Alexander D Blanchette, Fabian A Grimm, John S House, David M Reif

Toxicol Appl Pharmacol· October 2019

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Thorough QT/QTc in a Dish: An In Vitro Human Model That Accurately Predicts Clinical Concentration-QTc Relationships.
Alexander D Blanchette, Fabian A Grimm, Chimeddulam Dalaijamts, Nan-Hung Hsieh, Kyle Ferguson

Clin Pharmacol Ther· May 2019

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