Publications by authors named "Alexander D Gitlin"

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Independent mechanisms of inflammation and myeloid bias in VEXAS syndrome.
Varun K Narendra, Tandrila Das, Linsey J Wierciszewski, Rebecca J Londoner, Joshua K Morrison, Alexander D Gitlin

Nature· November 2025

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Regulated somatic hypermutation enhances antibody affinity maturation.
Julia Merkenschlager, Andrew G T Pyo, Gabriela S Silva Santos, Dennis Schaefer-Babajew, Melissa Cipolla, Alexander D Gitlin

Nature· May 2025

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N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation.
Alexander D Gitlin, Allie Maltzman, Yuzuka Kanno, Klaus Heger, Rohit Reja

Immunity· May 2024

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Deubiquitinases in cell death and inflammation.
Kim Newton, Alexander D Gitlin

Biochem J· May 2022

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Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine.
Chunfeng Li, Audrey Lee, Lilit Grigoryan, Prabhu S Arunachalam, Madeleine K D Scott, Alexander D Gitlin

Nat Immunol· April 2022

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Integration of innate immune signalling by caspase-8 cleavage of N4BP1.
Alexander D Gitlin, Klaus Heger, Alexander F Schubert, Rohit Reja, Donghong Yan

Nature· November 2020

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Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway.
Eui Ho Kim, Matthew C Woodruff, Lilit Grigoryan, Barbara Maier, Song Hee Lee, Alexander D Gitlin

Elife· June 2020

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ICAMs support B cell interactions with T follicular helper cells and promote clonal selection.
Irina Zaretsky, Ofir Atrakchi, Roei D Mazor, Liat Stoler-Barak, Adi Biram, Alexander D Gitlin

J Exp Med· November 2017

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The microanatomic segregation of selection by apoptosis in the germinal center.
Christian T Mayer, Anna Gazumyan, Ervin E Kara, Alexander D Gitlin, Jovana Golijanin

Science· October 2017

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Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.
Max Medina-Ramírez, Fernando Garces, Amelia Escolano, Patrick Skog, Steven W de Taeye, Alexander D Gitlin

J Exp Med· September 2017

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Sequencing and cloning of antigen-specific antibodies from mouse memory B cells.
Lotta von Boehmer, Cassie Liu, Sarah Ackerman, Alexander D Gitlin, Qiao Wang

Nat Protoc· October 2016

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Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice.
Amelia Escolano, Jon M Steichen, Pia Dosenovic, Daniel W Kulp, Jovana Golijanin, Alexander D Gitlin

Cell· September 2016

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HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.
Jon M Steichen, Daniel W Kulp, Talar Tokatlian, Amelia Escolano, Pia Dosenovic, Alexander D Gitlin

Immunity· September 2016

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Independent Roles of Switching and Hypermutation in the Development and Persistence of B Lymphocyte Memory.
Alexander D Gitlin, Lotta von Boehmer, Anna Gazumyan, Ziv Shulman, Thiago Y Oliveira

Immunity· April 2016

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Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice.
Andrew T McGuire, Matthew D Gray, Pia Dosenovic, Alexander D Gitlin, Natalia T Freund

Nat Commun· February 2016

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HUMORAL IMMUNITY. T cell help controls the speed of the cell cycle in germinal center B cells.
Alexander D Gitlin, Christian T Mayer, Thiago Y Oliveira, Ziv Shulman, Mathew J K Jones

Science· August 2015

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Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice.
Pia Dosenovic, Lotta von Boehmer, Amelia Escolano, Joseph Jardine, Natalia T Freund, Alexander D Gitlin

Cell· June 2015

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Immunology: Fifty years of B lymphocytes.
Alexander D Gitlin, Michel C Nussenzweig

Nature· January 2015

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Dynamic signaling by T follicular helper cells during germinal center B cell selection.
Ziv Shulman, Alexander D Gitlin, Jason S Weinstein, Begoña Lainez, Enric Esplugues

Science· August 2014

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Clonal selection in the germinal centre by regulated proliferation and hypermutation.
Alexander D Gitlin, Ziv Shulman, Michel C Nussenzweig

Nature· May 2014

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Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development.
Philipp C Rommel, David Bosque, Alexander D Gitlin, Gist F Croft, Nathaniel Heintz

PLoS One· February 2014

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HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice.
Joshua A Horwitz, Ariel Halper-Stromberg, Hugo Mouquet, Alexander D Gitlin, Anna Tretiakova

Proc Natl Acad Sci U S A· October 2013

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T follicular helper cell dynamics in germinal centers.
Ziv Shulman, Alexander D Gitlin, Sasha Targ, Mila Jankovic, Giulia Pasqual

Science· August 2013

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Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Michela Di Virgilio, Elsa Callen, Arito Yamane, Wenzhu Zhang, Mila Jankovic, Alexander D Gitlin

Science· February 2013

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Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells.
Stefan Kubicek, Joshua C Gilbert, Dina Fomina-Yadlin, Alexander D Gitlin, Yuan Yuan

Proc Natl Acad Sci U S A· April 2012

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