Publications by authors named "Fernando Garces"

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An Arrayed CRISPR Screen Identifies Knockout Combinations Improving Antibody Productivity in HEK293 Cells.
Eric Edward Bryant, Danyang Gong, Cai Guo, Fernando Garces, René Hubert

ACS Synth Biol· March 2025

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Next generation of multispecific antibody engineering.
Daniel Keri, Matt Walker, Isha Singh, Kyle Nishikawa, Fernando Garces

Antib Ther· January 2024

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Protocol for high-throughput cloning, expression, purification, and evaluation of bispecific antibodies.
Danqing Li, Alexander C Partin, Liangjun Zhao, Irwin Chen, Mark L Michaels, Fernando Garces

STAR Protoc· June 2022

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Next generation Fc scaffold for multispecific antibodies.
Bram Estes, Athena Sudom, Danyang Gong, Douglas A Whittington, Vivian Li, Fernando Garces

iScience· December 2021

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Identification of critical chemical modifications and paratope mapping by size exclusion chromatography of stressed antibody-target complexes.
Pavel Bondarenko, Andrew C Nichols, Gang Xiao, Rachel Liuqing Shi, Pik Kay Chan, Fernando Garces

MAbs· November 2021

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Rational selection of building blocks for the assembly of bispecific antibodies.
Danyang Gong, Timothy P Riley, Krzysztof P Bzymek, Ana R Correia, Danqing Li, Fernando Garces

MAbs· October 2021

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Enhancing the Prefusion Conformational Stability of SARS-CoV-2 Spike Protein Through Structure-Guided Design.
Timothy P Riley, Hui-Ting Chou, Ruozhen Hu, Krzysztof P Bzymek, Ana R Correia, Fernando Garces

Front Immunol· May 2021

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Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab).
Fernando Garces, Christopher Mohr, Li Zhang, Ching-Shin Huang, Qing Chen

Cell Rep· February 2020

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The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template.
Raiees Andrabi, Jesper Pallesen, Joel D Allen, Ge Song, Jinsong Zhang, Fernando Garces

Cell Rep· May 2019

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Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence.
Kwinten Sliepen, Byung Woo Han, Ilja Bontjer, Petra Mooij, Fernando Garces

Nat Commun· May 2019

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Efficient Single-Strand Break Repair Requires Binding to Both Poly(ADP-Ribose) and DNA by the Central BRCT Domain of XRCC1.
Luis M Polo, Yingqi Xu, Peter Hornyak, Fernando Garces, Zhihong Zeng

Cell Rep· January 2019

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Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model.
James E Voss, Raiees Andrabi, Laura E McCoy, Natalia de Val, Roberta P Fuller, Fernando Garces

Cell Rep· January 2018

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Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model.
James E Voss, Raiees Andrabi, Laura E McCoy, Natalia de Val, Roberta P Fuller, Fernando Garces

Cell Rep· October 2017

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Insights into the inhibited form of the redox-sensitive SufE-like sulfur acceptor CsdE.
Esther Peña-Soler, Juan Aranda, Miguel López-Estepa, Sara Gómez, Fernando Garces

PLoS One· October 2017

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Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.
Max Medina-Ramírez, Fernando Garces, Amelia Escolano, Patrick Skog, Steven W de Taeye

J Exp Med· September 2017

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Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.
Alba Torrents de la Peña, Jean-Philippe Julien, Steven W de Taeye, Fernando Garces, Miklos Guttman

Cell Rep· August 2017

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The path toward an HIV-1 vaccine.
Fernando Garces

Porto Biomed J· August 2017

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Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein.
Javier Guenaga, Fernando Garces, Natalia de Val, Robyn L Stanfield, Viktoriya Dubrovskaya

Immunity· May 2017

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Structural flexibility at a major conserved antibody target on hepatitis C virus E2 antigen.
Leopold Kong, David E Lee, Rameshwar U Kadam, Tong Liu, Erick Giang, Fernando Garces

Proc Natl Acad Sci U S A· November 2016

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HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.
Jon M Steichen, Daniel W Kulp, Talar Tokatlian, Amelia Escolano, Pia Dosenovic, Fernando Garces

Immunity· September 2016

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Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.
Daniel T MacLeod, Nancy M Choi, Bryan Briney, Fernando Garces, Lorena S Ver

Immunity· May 2016

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Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Leopold Kong, Bin Ju, Yajing Chen, Linling He, Li Ren, Fernando Garces

Immunity· April 2016

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Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Fernando Garces, Jeong Hyun Lee, Natalia de Val, Alba Torrents de la Pena, Leopold Kong

Immunity· December 2015

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Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.
Leopold Kong, Alba Torrents de la Peña, Marc C Deller, Fernando Garces, Kwinten Sliepen

Acta Crystallogr D Biol Crystallogr· October 2015

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Correction for Doores et al., Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope.
Katie J Doores, Leopold Kong, Stefanie A Krumm, Khoa M Le, Devin Sok, Fernando Garces

J Virol· June 2015

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