Publications by authors named "Alexander Faussner"

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Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive atherosclerosis.
Yvonne Döring, Emiel P C van der Vorst, Yi Yan, Carlos Neideck, Xavier Blanchet, Alexander Faussner

Nat Cardiovasc Res· February 2024

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GPR55 in B cells limits atherosclerosis development and regulates plasma cell maturation.
Raquel Guillamat-Prats, Daniel Hering, Abhishek Derle, Martina Rami, Carmen Härdtner, Alexander Faussner

Nat Cardiovasc Res· November 2022

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Direct addition of poly-lysine or poly-ethylenimine to the medium: A simple alternative to plate pre-coating.
Alexander Faussner, Matthias M Deininger, Christian Weber, Sabine Steffens

PLoS One· July 2022

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In vitro pharmacological profile of PHA-022121, a small molecule bradykinin B receptor antagonist in clinical development.
Anne Lesage, François Marceau, Christoph Gibson, Brigitte Loenders, Werner Katzer, Alexander Faussner

Int Immunopharmacol· April 2022

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Chemokines and galectins form heterodimers to modulate inflammation.
Veit Eckardt, Michelle C Miller, Xavier Blanchet, Rundan Duan, Julian Leberzammer, Alexander Faussner

EMBO Rep· April 2020

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Deficiency of Monoacylglycerol Lipase Enhances IgM Plasma Levels and Limits Atherogenesis in a CB2-Dependent Manner.
Raquel Guillamat Prats, Martina Rami, Larisa Ring, Petteri Rinne, Estelle Lauer, Alexander Faussner

Thromb Haemost· February 2019

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Chronic Intake of the Selective Serotonin Reuptake Inhibitor Fluoxetine Enhances Atherosclerosis.
Martina Rami, Raquel Guillamat-Prats, Petteri Rinne, Melanie Salvermoser, Larisa Ring, Alexander Faussner

Arterioscler Thromb Vasc Biol· May 2018

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CD27 co-stimulation increases the abundance of regulatory T cells and reduces atherosclerosis in hyperlipidaemic mice.
Holger Winkels, Svenja Meiler, Dirk Lievens, David Engel, Charlotte Spitz, Alexander Faussner

Eur Heart J· December 2017

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Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.
Philipp von Hundelshausen, Stijn M Agten, Veit Eckardt, Xavier Blanchet, Martin M Schmitt, Alexander Faussner

Sci Transl Med· April 2017

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CD70 limits atherosclerosis and promotes macrophage function.
Holger Winkels, Svenja Meiler, Esther Smeets, Dirk Lievens, David Engel, Alexander Faussner

Thromb Haemost· January 2017

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Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation.
Manuela Mandl, Maik Drechsler, Yvonne Jansen, Carlos Neideck, Heidi Noels, Alexander Faussner

PLoS One· May 2016

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Cross-Linking GPVI-Fc by Anti-Fc Antibodies Potentiates Its Inhibition of Atherosclerotic Plaque- and Collagen-Induced Platelet Activation.
Janina Jamasbi, Remco T A Megens, Mariaelvy Bianchini, Kerstin Uhland, Götz Münch, Alexander Faussner

JACC Basic Transl Sci· April 2016

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Differential Inhibition of Human Atherosclerotic Plaque-Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies: Functional and Imaging Studies.
Janina Jamasbi, Remco T A Megens, Mariaelvy Bianchini, Götz Münch, Martin Ungerer, Alexander Faussner

J Am Coll Cardiol· June 2015

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Kinin release from human kininogen by 10 aspartic proteases produced by pathogenic yeast Candida albicans.
Andrzej Kozik, Mariusz Gogol, Oliwia Bochenska, Justyna Karkowska-Kuleta, Natalia Wolak, Alexander Faussner

BMC Microbiol· March 2015

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Kinin-generating cellular model obtained from human glioblastoma cell line U-373.
Ibeth Guevara-Lora, Beata Blonska, Alexander Faussner, Andrzej Kozik

Acta Biochim Pol· April 2014

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β-Catenin-dependent pathway activation by both promiscuous "canonical" WNT3a-, and specific "noncanonical" WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 dependency.
Larisa Ring, Peter Neth, Christian Weber, Sabine Steffens, Alexander Faussner

Cell Signal· February 2014

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Release of biologically active kinin peptides, Met-Lys-bradykinin and Leu-Met-Lys-bradykinin from human kininogens by two major secreted aspartic proteases of Candida parapsilosis.
Grazyna Bras, Oliwia Bochenska, Maria Rapala-Kozik, Ibeth Guevara-Lora, Alexander Faussner

Peptides· October 2013

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Interruption of the ionic lock in the bradykinin B2 receptor results in constitutive internalization and turns several antagonists into strong agonists.
Jasmin Leschner, Goeran Wennerberg, Jens Feierler, Marcel Bermudez, Benjamin Welte, Alexander Faussner

J Pharmacol Exp Ther· January 2013

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Extracellular aspartic protease SAP2 of Candida albicans yeast cleaves human kininogens and releases proinflammatory peptides, Met-Lys-bradykinin and des-Arg(9)-Met-Lys-bradykinin.
Grazyna Bras, Oliwia Bochenska, Maria Rapala-Kozik, Ibeth Guevara-Lora, Alexander Faussner

Biol Chem· August 2012

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Helix 8 plays a crucial role in bradykinin B(2) receptor trafficking and signaling.
Jens Feierler, Markus Wirth, Benjamin Welte, Steffen Schüssler, Marianne Jochum, Alexander Faussner

J Biol Chem· December 2011

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Reporter gene HEK 293 cells and WNT/Frizzled fusion proteins as tools to study WNT signaling pathways.
Larisa Ring, Iris Peröbner, Marisa Karow, Marianne Jochum, Peter Neth, Alexander Faussner

Biol Chem· November 2011

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Fever-like temperature modification differentially affects in vitro signaling of bradykinin B(1) and B(2) receptors.
Jasmin Leschner, Larisa Ring, Jens Feierler, Klaus Dinkel, Marianne Jochum, Alexander Faussner

Biol Chem· November 2011

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Kinin generation from exogenous kininogens at the surface of retinoic acid-differentiated human neuroblastoma IMR-32 cells after stimulation with interferon-γ.
Ibeth Guevara-Lora, Magdalena Majkucinska, Anna Barbasz, Alexander Faussner, Andrzej Kozik

Peptides· June 2011

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Degradation of human kininogens with the release of kinin peptides by extracellular proteinases of Candida spp.
Maria Rapala-Kozik, Justyna Karkowska-Kuleta, Agnieszka Ryzanowska, Anna Golda, Anna Barbasz, Alexander Faussner

Biol Chem· July 2010

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A cysteine-type carboxypeptidase, cathepsin X, generates peptide receptor agonists.
Dorit K Nägler, Steffen Kraus, Jens Feierler, Reinhard Mentele, Friedrich Lottspeich, Alexander Faussner

Int Immunopharmacol· January 2010

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