Publications by authors named "Alexander Fish"

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Late-onset epilepsy of unknown etiology is more treatment-responsive than acquired lesional late-onset epilepsy.
L Brian Hickman, Bhavya Pandey, Alexander Fish, Mohit Bandla, Adnan Husein

Epilepsia Open· December 2025

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Toward an ion-based large-scale integrated circuit: design, simulation, and integration.
Noa Edri Fraiman, Barak Sabbagh, Gilad Yossifon, Alexander Fish

Commun Eng· October 2025

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NASP modulates histone turnover to drive PARP inhibitor resistance.
Sarah C Moser, Anna Khalizieva, Josef Roehsner, Elisabeth Pottendorfer, Milo L Kaptein, Alexander Fish

Nature· September 2025

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USP1/UAF1 targets polyubiquitinated PCNA with an exo-cleavage mechanism that can temporarily enrich for monoubiquitinated PCNA.
Niels Keijzer, Jan Sakoltchik, Kaustav Majumder, Nina van Lil, Farid El Oualid, Alexander Fish

Nat Commun· July 2025

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SRBD1, a highly conserved gene required for chromosome individualization.
Jonne A Raaijmakers, Louise M E Janssen, Abdelghani Mazouzi, Amber L H Hondema, Razvan Borza, Alexander Fish

Cell Rep· April 2025

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Content analysis of Reddit posts about coadministration of selective serotonin reuptake inhibitors and psilocybin mushrooms.
Kimberly Sakai, Ellen R Bradley, Joseph A Zamaria, Gabrielle Agin-Liebes, D Parker Kelley, Alexander Fish

Psychopharmacology (Berl)· August 2024

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Variety in the USP deubiquitinase catalytic mechanism.
Niels Keijzer, Anu Priyanka, Yvette Stijf-Bultsma, Alexander Fish, Malte Gersch

Life Sci Alliance· April 2024

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Unconventional life history in a migratory shorebird: desegregating reproduction and migration.
Colby R Slezak, Erik J Blomberg, Amber M Roth, Liam A Berigan, Alexander C Fish

Proc Biol Sci· April 2024

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Unexpected moves: a conformational change in MutSα enables high-affinity DNA mismatch binding.
Susanne R Bruekner, Wietske Pieters, Alexander Fish, A Manuel Liaci, Serge Scheffers

Nucleic Acids Res· February 2023

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Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells.
Nikolaos Karantzelis, Michalis Petropoulos, Valeria De Marco, David A Egan, Alexander Fish

Front Pharmacol· April 2022

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Correction to: Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study.
Blanca López-Méndez, Bruno Baron, Chad A Brautigam, Thomas A Jowitt, Stefan H Knauer, Alexander Fish

Eur Biophys J· December 2021

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Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study.
Blanca López-Méndez, Bruno Baron, Chad A Brautigam, Thomas A Jowitt, Stefan H Knauer, Alexander Fish

Eur Biophys J· May 2021

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Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery.
Misbha Ud Din Ahmad, Alexander Fish, Jeroen Molenaar, Sridhar Sreeramulu, Christian Richter

J Vis Exp· May 2021

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Insert L1 is a central hub for allosteric regulation of USP1 activity.
Shreya Dharadhar, Willem J van Dijk, Serge Scheffers, Alexander Fish, Titia K Sixma

EMBO Rep· April 2021

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The selection process of licensing a DNA mismatch for repair.
Rafael Fernandez-Leiro, Doreth Bhairosing-Kok, Vladislav Kunetsky, Charlie Laffeber, Herrie H Winterwerp, Alexander Fish

Nat Struct Mol Biol· April 2021

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K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap.
Gabriëlle B A van Tilburg, Andrea G Murachelli, Alexander Fish, Gerbrand J van der Heden van Noort, Huib Ovaa

Cell Chem Biol· February 2021

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Natural Killer Cell Activation Receptor NKp30 Oligomerization Depends on Its -Glycosylation.
Ondřej Skořepa, Samuel Pazicky, Barbora Kalousková, Jan Bláha, Celeste Abreu, Alexander Fish

Cancers (Basel)· July 2020

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A fragment-like approach to PYCR1 inhibition.
Kirsty Milne, Jianhui Sun, Esther A Zaal, Jenna Mowat, Patrick H N Celie, Alexander Fish

Bioorg Med Chem Lett· September 2019

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Sharp kinking of a coiled-coil in MutS allows DNA binding and release.
Doreth Bhairosing-Kok, Flora S Groothuizen, Alexander Fish, Shreya Dharadhar, Herrie H K Winterwerp

Nucleic Acids Res· September 2019

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Fluorescence-guided tumor detection with a novel anti-EpCAM targeted antibody fragment: Preclinical validation.
Leonora S F Boogerd, Martin C Boonstra, Hendrica A J M Prevoo, Henricus J M Handgraaf, Peter J K Kuppen, Alexander Fish

Surg Oncol· March 2019

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Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity.
Robbert Q Kim, Paul P Geurink, Monique P C Mulder, Alexander Fish, Reggy Ekkebus

Nat Commun· January 2019

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Characterization and structure determination of a llama-derived nanobody targeting the J-base binding protein 1.
Bart van Beusekom, Tatjana Heidebrecht, Athanassios Adamopoulos, Alexander Fish, Els Pardon

Acta Crystallogr F Struct Biol Commun· November 2018

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Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis.
Carlos Sacristan, Misbha Ud Din Ahmad, Jenny Keller, Job Fermie, Vincent Groenewold, Alexander Fish

Nat Cell Biol· July 2018

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USP48 restrains resection by site-specific cleavage of the BRCA1 ubiquitin mark from H2A.
Michael Uckelmann, Ruth M Densham, Roy Baas, Herrie H K Winterwerp, Alexander Fish

Nat Commun· January 2018

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A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme.
Shreya Dharadhar, Marcello Clerici, Willem J van Dijk, Alexander Fish, Titia K Sixma

J Struct Biol· December 2016

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