Publications by authors named "Robbert Q Kim"

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Development and Validation of a High-Throughput Screening Assay for the Legionella ADP-Ribosyl Transferase SdeA.
Halana C Vlaming, Vito Pol, Bjorn R van Doodewaerd, Angeliki Moutsiopoulou, Paul P Geurink, Robbert Q Kim

Chembiochem· November 2025

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Structural and mechanistic study of a novel inhibitor analogue of cytochrome bc:aa.
Amit K Verma, Robbert Q Kim, Dirk A Lamprecht, Clara Aguilar-Pérez, Sarah Wong

NPJ Drug Discov· April 2025

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Covalent Probes To Capture Dup Effector Enzymes.
Max S Kloet, Rishov Mukhopadhyay, Rukmini Mukherjee, Mohit Misra, Minwoo Jeong, Robbert Q Kim

J Am Chem Soc· October 2024

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Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell.
Yuqing Jia, Merve Oyken, Robbert Q Kim, Rayman T N Tjokrodirijo, Arnoud H de Ru

J Med Chem· May 2024

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RNF26 binds perinuclear vimentin filaments to integrate ER and endolysosomal responses to proteotoxic stress.
Tom Cremer, Lenard M Voortman, Erik Bos, Marlieke Lm Jongsma, Laurens R Ter Haar, Robbert Q Kim

EMBO J· September 2023

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Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2.
Jin Gan, Jelle de Vries, Jimmy J L L Akkermans, Yassene Mohammed, Rayman T N Tjokrodirijo, Robbert Q Kim

ACS Chem Biol· September 2023

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Comparison of methods generating antibody-epitope conjugates for targeting cancer with virus-specific T cells.
Willemijn van der Wulp, Anna M Gram, Boris Bleijlevens, Renate S Hagedoorn, Can Araman, Robbert Q Kim

Front Immunol· June 2023

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Technologies for Direct Detection of Covalent Protein-Drug Adducts.
Elma Mons, Robbert Q Kim, Monique P C Mulder

Pharmaceuticals (Basel)· April 2023

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Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymes.
Bianca D M van Tol, Bjorn R van Doodewaerd, Guinevere S M Lageveen-Kammeijer, Bas C Jansen, Cami M P Talavera Ormeño, Robbert Q Kim

Nat Commun· March 2023

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Arginine ADP-Ribosylation: Chemical Synthesis of Post-Translationally Modified Ubiquitin Proteins.
Jim Voorneveld, Max S Kloet, Sven Wijngaarden, Robbert Q Kim, Angeliki Moutsiopoulou

J Am Chem Soc· November 2022

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Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput.
Yuqing Jia, Robbert Q Kim, Raymond Kooij, Huib Ovaa, Aysegul Sapmaz

J Med Chem· October 2022

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Malaria parasite evades mosquito immunity by glutaminyl cyclase-mediated posttranslational protein modification.
Surendra Kumar Kolli, Alvaro Molina-Cruz, Tamasa Araki, Fiona J A Geurten, Jai Ramesar, Robbert Q Kim

Proc Natl Acad Sci U S A· August 2022

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A Comprehensive Guide for Assessing Covalent Inhibition in Enzymatic Assays Illustrated with Kinetic Simulations.
Elma Mons, Sander Roet, Robbert Q Kim, Monique P C Mulder

Curr Protoc· June 2022

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Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining.
Jenny Kaur Singh, Rebecca Smith, Magdalena B Rother, Anton J L de Groot, Wouter W Wiegant, Robbert Q Kim

Nat Commun· November 2021

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Exploring the Versatility of the Covalent Thiol-Alkyne Reaction with Substituted Propargyl Warheads: A Deciding Role for the Cysteine Protease.
Elma Mons, Robbert Q Kim, Bjorn R van Doodewaerd, Peter A van Veelen, Monique P C Mulder

J Am Chem Soc· May 2021

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Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection.
Robbert Q Kim, Mohit Misra, Alexis Gonzalez, Ines Tomašković, Donghyuk Shin

Chemistry· February 2021

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Synthesis of Stable NAD Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitylating Enzyme SdeC.
Jerre M Madern, Robbert Q Kim, Mohit Misra, Ivan Dikic, Yong Zhang

Chembiochem· October 2020

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Quantitative analysis of USP activity in vitro.
Shreya Dharadhar, Robbert Q Kim, Michael Uckelmann, Titia K Sixma

Methods Enzymol· November 2019

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Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity.
Robbert Q Kim, Paul P Geurink, Monique P C Mulder, Alexander Fish, Reggy Ekkebus

Nat Commun· January 2019

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Regulation of USP7: A High Incidence of E3 Complexes.
Robbert Q Kim, Titia K Sixma

J Mol Biol· November 2017

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Structure of USP7 catalytic domain and three Ubl-domains reveals a connector α-helix with regulatory role.
Robbert Q Kim, Willem J van Dijk, Titia K Sixma

J Struct Biol· July 2016

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Structural enzymology of Helicobacter pylori methylthioadenosine nucleosidase in the futalosine pathway.
Robbert Q Kim, Wendy A Offen, Gideon J Davies, Keith A Stubbs

Acta Crystallogr D Biol Crystallogr· January 2014

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The copper active site of CBM33 polysaccharide oxygenases.
Glyn R Hemsworth, Edward J Taylor, Robbert Q Kim, Rebecca C Gregory, Sally J Lewis

J Am Chem Soc· April 2013

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