Publications by authors named "Alexander Hoepping"

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Efficacy of [F]PSMA-1007 PET/CT in Primary Staging of Prostate Carcinoma: A Systematic Review and Metaanalysis.
Kambiz Rahbar, Frederik L Giesel, Ken Herrmann, Mijin Yun, Tadashi Watabe, Alexander Hoepping

J Nucl Med· October 2025

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A cost-effectiveness study of PSMA-PET/CT for the detection of clinically significant prostate cancer.
Bastiaan M Privé, Tim M Govers, Bas Israël, Marcel J R Janssen, Bart J R Timmermans, Alexander Hoepping

Eur J Nucl Med Mol Imaging· July 2025

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Development of [Tc]TcO-ABX474: Design, Synthesis, and Biological Evaluation of PSMA-Binding Technetium-99m Radioligands for SPECT Imaging of Prostate Cancer.
Christian Lis, Friedrich-Alexander Ludwig, Steffen Fischer, Martin Ullrich, Hans-Joachim Lankau, Alexander Hoepping

J Med Chem· April 2025

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Combination of [F]FDG and [F]PSMA-1007 PET/CT predicts tumour aggressiveness at staging and biochemical failure postoperatively in patients with prostate cancer.
Jisu Kim, Seunghwan Lee, Dongwoo Kim, Hyun Jeong Kim, Kyeong Taek Oh, Alexander Hoepping

Eur J Nucl Med Mol Imaging· May 2024

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Multiparametric MRI and F-PSMA-1007 PET/CT for the Detection of Clinically Significant Prostate Cancer.
Bastiaan M Privé, Bas Israël, Marcel J R Janssen, Marloes M G van der Leest, Maarten de Rooij, Alexander Hoepping

Radiology· May 2024

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Phase III Study of F-PSMA-1007 Versus F-Fluorocholine PET/CT for Localization of Prostate Cancer Biochemical Recurrence: A Prospective, Randomized, Crossover Multicenter Study.
Pierre Olivier, Anne-Laure Giraudet, Andrea Skanjeti, Charles Merlin, Pierre Weinmann, Alexander Hoepping

J Nucl Med· April 2023

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Preclinical Evaluation of a Companion Diagnostic Radiopharmaceutical, [F]PSMA-1007, in a Subcutaneous Prostate Cancer Xenograft Mouse Model.
Su Bin Kim, In Ho Song, Seon Yoo Kim, Hae Young Ko, Hee Seup Kil, Alexander Hoepping

Mol Pharm· February 2023

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An Explorative Study of the Incidental High Renal Excretion of [F]PSMA-1007 for Prostate Cancer PET/CT Imaging.
Youssra Allach, Amina Banda, Willemijn van Gemert, Michel de Groot, Yvonne Derks, Alexander Hoepping

Cancers (Basel)· April 2022

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(+)-[F]Flubatine as a novel α4β2 nicotinic acetylcholine receptor PET ligand-results of the first-in-human brain imaging application in patients with β-amyloid PET-confirmed Alzheimer's disease and healthy controls.
Solveig Tiepolt, Georg-Alexander Becker, Stephan Wilke, Diego Cecchin, Michael Rullmann, Alexander Hoepping

Eur J Nucl Med Mol Imaging· March 2021

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and Human Metabolism of ()-[F]Fluspidine - A Radioligand for Imaging σ Receptors With Positron Emission Tomography (PET).
Friedrich-Alexander Ludwig, Steffen Fischer, Richard Houska, Alexander Hoepping, Winnie Deuther-Conrad

Front Pharmacol· June 2019

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Image-Guided Development of Heterocyclic Sulfoxides as Ligands for Tau Neurofibrillary Tangles: From First-in-Man to Second-Generation Ligands.
Waqas Rafique, Vasko Kramer, Tania Pardo, René Smits, Mona M Spilhaug, Alexander Hoepping

ACS Omega· July 2018

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Cognitive correlates of α4β2 nicotinic acetylcholine receptors in mild Alzheimer's dementia.
Osama Sabri, Philipp M Meyer, Susanne Gräf, Swen Hesse, Stephan Wilke, Alexander Hoepping

Brain· June 2018

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Exploring the Metabolism of (+)-[F]Flubatine in Vitro and in Vivo: LC-MS/MS Aided Identification of Radiometabolites in a Clinical PET Study.
Friedrich-Alexander Ludwig, Steffen Fischer, René Smits, Winnie Deuther-Conrad, Alexander Hoepping

Molecules· February 2018

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Procedures for the GMP-Compliant Production and Quality Control of [F]PSMA-1007: A Next Generation Radiofluorinated Tracer for the Detection of Prostate Cancer.
Jens Cardinale, René Martin, Yvonne Remde, Martin Schäfer, Antje Hienzsch, Alexander Hoepping

Pharmaceuticals (Basel)· September 2017

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Radiation dosimetry of the αβ nicotinic receptor ligand (+)-[F]flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results.
Mathias Kranz, Bernhard Sattler, Solveig Tiepolt, Stephan Wilke, Winnie Deuther-Conrad, Alexander Hoepping

EJNMMI Phys· December 2016

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LC-MS Supported Studies on the in Vitro Metabolism of both Enantiomers of Flubatine and the in Vivo Metabolism of (+)-[(18)F]Flubatine-A Positron Emission Tomography Radioligand for Imaging α4β2 Nicotinic Acetylcholine Receptors.
Friedrich-Alexander Ludwig, René Smits, Steffen Fischer, Cornelius K Donat, Alexander Hoepping

Molecules· September 2016

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Enhanced copper-mediated (18)F-fluorination of aryl boronic esters provides eight radiotracers for PET applications.
Sean Preshlock, Samuel Calderwood, Stefan Verhoog, Matthew Tredwell, Mickael Huiban, Alexander Hoepping

Chem Commun (Camb)· June 2016

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Development of a Novel Nonpeptidic (18)F-Labeled Radiotracer for in Vivo Imaging of Oxytocin Receptors with Positron Emission Tomography.
Barbara Wenzel, Jan Mollitor, Winnie Deuther-Conrad, Sladjana Dukic-Stefanovic, Mathias Kranz, Alexander Hoepping

J Med Chem· March 2016

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Radiosynthesis and first preclinical evaluation of the novel norepinephrine transporter pet-ligand [(11)C]ME@HAPTHI.
Christina Rami-Mark, Neydher Berroterán-Infante, Cecile Philippe, Stefanie Foltin, Chrysoula Vraka, Alexander Hoepping

EJNMMI Res· December 2015

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First-in-human PET quantification study of cerebral α4β2* nicotinic acetylcholine receptors using the novel specific radioligand (-)-[(18)F]Flubatine.
Osama Sabri, Georg-Alexander Becker, Philipp M Meyer, Swen Hesse, Stephan Wilke, Alexander Hoepping

Neuroimage· September 2015

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Internal dose assessment of (-)-18F-flubatine, comparing animal model datasets of mice and piglets with first-in-human results.
Bernhard Sattler, Mathias Kranz, Alexander Starke, Stephan Wilke, Cornelius K Donat, Alexander Hoepping

J Nucl Med· November 2014

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Evaluation of metabolism, plasma protein binding and other biological parameters after administration of (-)-[(18)F]Flubatine in humans.
Marianne Patt, Georg A Becker, Udo Grossmann, Bernd Habermann, Andreas Schildan, Alexander Hoepping

Nucl Med Biol· July 2014

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Synthesis and biological evaluation of both enantiomers of [(18)F]flubatine, promising radiotracers with fast kinetics for the imaging of α4β2-nicotinic acetylcholine receptors.
René Smits, Steffen Fischer, Achim Hiller, Winnie Deuther-Conrad, Barbara Wenzel, Alexander Hoepping

Bioorg Med Chem· January 2014

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Fully automated radiosynthesis of both enantiomers of [18F]Flubatine under GMP conditions for human application.
Marianne Patt, Andreas Schildan, Bernd Habermann, Steffen Fischer, Achim Hiller, Alexander Hoepping

Appl Radiat Isot· October 2013

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Radiosynthesis of racemic and enantiomerically pure (-)-[18F]flubatine--a promising PET radiotracer for neuroimaging of α4β2 nicotinic acetylcholine receptors.
Steffen Fischer, Achim Hiller, René Smits, Alexander Hoepping, Uta Funke

Appl Radiat Isot· April 2013

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