Publications by authors named "Alexander Mackie"

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Biologic outcomes in U.S. Hispanic and Black patients with severe asthma.
Jennifer Trevor, Wendy C Moore, Njira Lugogo, Dennis K Ledford, Alexander Mackie

J Allergy Clin Immunol Pract· October 2024

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Reduced Effectiveness of Anti-IgE Treatment Among Adults with Severe Asthma with Older Age of Asthma Onset: Results from the CHRONICLE Study.
Dennis K Ledford, Warner W Carr, Wendy C Moore, Njira L Lugogo, Arjun Mohan, Alexander R Mackie

J Asthma Allergy· October 2024

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Endothelial smoothened-dependent hedgehog signaling is not required for sonic hedgehog induced angiogenesis or ischemic tissue repair.
Rajesh Gupta, Alexander R Mackie, Sol Misener, Lijun Liu, Douglas W Losordo

Lab Invest· May 2018

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Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan.
Rahul Rai, Asish K Ghosh, Mesut Eren, Alexander R Mackie, Daniel C Levine

Cell Rep· November 2017

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Negative Regulation of miR-375 by Interleukin-10 Enhances Bone Marrow-Derived Progenitor Cell-Mediated Myocardial Repair and Function After Myocardial Infarction.
Venkata Naga Srikanth Garikipati, Prasanna Krishnamurthy, Suresh Kumar Verma, Mohsin Khan, Tatiana Abramova, Alexander R Mackie

Stem Cells· December 2015

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Enhanced Cardiac Regenerative Ability of Stem Cells After Ischemia-Reperfusion Injury: Role of Human CD34+ Cells Deficient in MicroRNA-377.
Darukeshwara Joladarashi, Venkata Naga Srikanth Garikipati, Rajarajan A Thandavarayan, Suresh K Verma, Alexander R Mackie

J Am Coll Cardiol· November 2015

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Sirtuin-6 deficiency exacerbates diabetes-induced impairment of wound healing.
Rajarajan A Thandavarayan, Venkata Naga Srikanth Garikipati, Darukeshwara Joladarashi, Sahana Suresh Babu, Prince Jeyabal, Alexander R Mackie

Exp Dermatol· October 2015

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Therapeutic manipulation of angiogenesis with miR-27b.
Dorina Veliceasa, Dauren Biyashev, Gangjian Qin, Sol Misener, Alexander Roy Mackie

Vasc Cell· July 2015

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Embryonic stem cell-derived exosomes promote endogenous repair mechanisms and enhance cardiac function following myocardial infarction.
Mohsin Khan, Emily Nickoloff, Tatiana Abramova, Jennifer Johnson, Suresh Kumar Verma, Alexander Roy Mackie

Circ Res· June 2015

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E2F1 suppresses cardiac neovascularization by down-regulating VEGF and PlGF expression.
Min Wu, Junlan Zhou, Min Cheng, Chan Boriboun, Dauren Biyashev, Alexander Mackie

Cardiovasc Res· December 2014

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Differential protein kinase C-dependent modulation of Kv7.4 and Kv7.5 subunits of vascular Kv7 channels.
Lioubov I Brueggemann, Alexander R Mackie, Leanne L Cribbs, Jessica Freda, Abhishek Tripathi

J Biol Chem· January 2014

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Bone marrow progenitor cell therapy-mediated paracrine regulation of cardiac miRNA-155 modulates fibrotic response in diabetic hearts.
Raj Kishore, Suresh K Verma, Alexander R Mackie, Erin E Vaughan, Tatiana V Abramova

PLoS One· September 2013

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Alcohol consumption negates estrogen-mediated myocardial repair in ovariectomized mice by inhibiting endothelial progenitor cell mobilization and function.
Alexander R Mackie, Prasanna Krishnamurthy, Suresh K Verma, Tina Thorne, Veronica Ramirez

J Biol Chem· June 2013

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Elucidation of a novel pathway through which HDAC1 controls cardiomyocyte differentiation through expression of SOX-17 and BMP2.
Eneda Hoxha, Erin Lambers, John A Wasserstrom, Alexander Mackie, Veronica Ramirez

PLoS One· March 2013

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CD34-positive stem cells: in the treatment of heart and vascular disease in human beings.
Alexander R Mackie, Douglas W Losordo

Tex Heart Inst J· November 2012

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Sonic hedgehog-modified human CD34+ cells preserve cardiac function after acute myocardial infarction.
Alexander R Mackie, Ekaterina Klyachko, Tina Thorne, Kathryn M Schultz, Meredith Millay

Circ Res· July 2012

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Enhanced angiogenic and cardiomyocyte differentiation capacity of epigenetically reprogrammed mouse and human endothelial progenitor cells augments their efficacy for ischemic myocardial repair.
Melissa A Thal, Prasanna Krishnamurthy, Alexander R Mackie, Eneda Hoxha, Erin Lambers

Circ Res· July 2012

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Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-κB.
Suresh Kumar Verma, Prasanna Krishnamurthy, David Barefield, Neha Singh, Rajesh Gupta, Alexander Mackie

Circulation· July 2012

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Diclofenac distinguishes among homomeric and heteromeric potassium channels composed of KCNQ4 and KCNQ5 subunits.
Lioubov I Brueggemann, Alexander R Mackie, Jody L Martin, Leanne L Cribbs, Kenneth L Byron

Mol Pharmacol· January 2011

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Novel Actions of Nonsteroidal Anti-Inflammatory Drugs on Vascular Ion Channels: Accounting for Cardiovascular Side Effects and Identifying New Therapeutic Applications.
Lioubov I Brueggemann, Bharath K Mani, Alexander R Mackie, Leanne L Cribbs, Kenneth L Byron

Mol Cell Pharmacol· January 2010

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Differential effects of selective cyclooxygenase-2 inhibitors on vascular smooth muscle ion channels may account for differences in cardiovascular risk profiles.
Lioubov I Brueggemann, Alexander R Mackie, Bharath K Mani, Leanne L Cribbs, Kenneth L Byron

Mol Pharmacol· November 2009

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Cardiovascular KCNQ (Kv7) potassium channels: physiological regulators and new targets for therapeutic intervention.
Alexander R Mackie, Kenneth L Byron

Mol Pharmacol· November 2008

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Vascular KCNQ potassium channels as novel targets for the control of mesenteric artery constriction by vasopressin, based on studies in single cells, pressurized arteries, and in vivo measurements of mesenteric vascular resistance.
Alexander R Mackie, Lioubov I Brueggemann, Kyle K Henderson, Aaron J Shiels, Leanne L Cribbs

J Pharmacol Exp Ther· May 2008

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Changes in accumbal and pallidal pCREB and deltaFosB in morphine-sensitized rats: correlations with receptor-evoked electrophysiological measures in the ventral pallidum.
John McDaid, Jeanine E Dallimore, Alexander R Mackie, T Celeste Napier

Neuropsychopharmacology· June 2006

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