Publications by authors named "Alexander N Plotnikov"

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Identification of a biologically active fragment of ALK and LTK-Ligand 2 (augmentor-α).
Andrey V Reshetnyak, Jyotidarsini Mohanty, Francisco Tomé, David E Puleo, Alexander N Plotnikov

Proc Natl Acad Sci U S A· August 2018

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BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice.
Kalung Cheung, Geming Lu, Rajal Sharma, Adam Vincek, Ruihua Zhang, Alexander N Plotnikov

Proc Natl Acad Sci U S A· March 2017

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Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.
Chunyan Ren, Keita Morohashi, Alexander N Plotnikov, Jean Jakoncic, Steven G Smith

Chem Biol· February 2015

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Selective chemical modulation of gene transcription favors oligodendrocyte lineage progression.
Mar Gacias, Guillermo Gerona-Navarro, Alexander N Plotnikov, Guangtao Zhang, Lei Zeng

Chem Biol· July 2014

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Structural insights into acetylated-histone H4 recognition by the bromodomain-PHD finger module of human transcriptional coactivator CBP.
Alexander N Plotnikov, Shuai Yang, Thomas Jiachi Zhou, Elena Rusinova, Antonio Frasca

Structure· February 2014

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Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains.
Guangtao Zhang, Alexander N Plotnikov, Elena Rusinova, Tong Shen, Keita Morohashi

J Med Chem· November 2013

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Down-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibition.
Guangtao Zhang, Ruijie Liu, Yifei Zhong, Alexander N Plotnikov, Weijia Zhang

J Biol Chem· August 2012

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Structural basis for substrate specificity and catalysis of human histone acetyltransferase 1.
Hong Wu, Natasha Moshkina, Jinrong Min, Hong Zeng, Jennifer Joshua, Alexander N Plotnikov

Proc Natl Acad Sci U S A· June 2012

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Recycling of methylthioadenosine is essential for normal vascular development and reproduction in Arabidopsis.
Ishari Waduwara-Jayabahu, Yasmin Oppermann, Markus Wirtz, Zachary T Hull, Sarah Schoor, Alexander N Plotnikov

Plant Physiol· April 2012

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Rational design of cyclic peptide modulators of the transcriptional coactivator CBP: a new class of p53 inhibitors.
Guillermo Gerona-Navarro, Yoel-Rodríguez, Shiraz Mujtaba, Antonio Frasca, Jigneshkumar Patel, Alexander N Plotnikov

J Am Chem Soc· February 2011

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Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.
Lei Zeng, Qiang Zhang, Side Li, Alexander N Plotnikov, Martin J Walsh

Nature· July 2010

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Structural biology of human H3K9 methyltransferases.
Hong Wu, Jinrong Min, Vladimir V Lunin, Tatiana Antoshenko, Ludmila Dombrovski, Alexander N Plotnikov

PLoS One· January 2010

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Biochemical profiling of histone binding selectivity of the yeast bromodomain family.
Qiang Zhang, Suvobrata Chakravarty, Dario Ghersi, Lei Zeng, Alexander N Plotnikov

PLoS One· January 2010

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Crystal structures of human CDY proteins reveal a crotonase-like fold.
Hong Wu, Jinrong Min, Tatiana Antoshenko, Alexander N Plotnikov

Proteins· September 2009

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An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene.
Wolfram Tempel, Hong Wu, Ludmila Dombrovsky, Hong Zeng, Peter Loppnau, Alexander N Plotnikov

Proteins· February 2009

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The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBbeta.
Keith I Pardee, Xiaohui Xu, Jeff Reinking, Anja Schuetz, Aiping Dong, Alexander N Plotnikov

PLoS Biol· February 2009

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Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent.
Dean R Artis, Jack J Lin, Chao Zhang, Weiru Wang, Upasana Mehra, Alexander N Plotnikov

Proc Natl Acad Sci U S A· January 2009

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Structural and kinetic differences between human and Aspergillus fumigatus D-glucosamine-6-phosphate N-acetyltransferase.
Ramon Hurtado-Guerrero, Olawale G Raimi, Jinrong Min, Hong Zeng, Laura Vallius, Alexander N Plotnikov

Biochem J· October 2008

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Crystal structure of the methyltransferase domain of human TARBP1.
Hong Wu, Jinrong Min, Hong Zeng, Alexander N Plotnikov

Proteins· July 2008

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Crystal structure of human spermine synthase: implications of substrate binding and catalytic mechanism.
Hong Wu, Jinrong Min, Hong Zeng, Diane E McCloskey, Yoshihiko Ikeguchi, Alexander N Plotnikov

J Biol Chem· June 2008

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Structural analysis of CYP2R1 in complex with vitamin D3.
Natallia Strushkevich, Sergey A Usanov, Alexander N Plotnikov, Glenville Jones, Hee-Won Park

J Mol Biol· June 2008

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Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity.
Anja Schuetz, Jinrong Min, Abdellah Allali-Hassani, Matthieu Schapira, Michael Shuen, Alexander N Plotnikov

J Biol Chem· April 2008

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Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases.
Hong Wu, Ludmila Dombrovsky, Wolfram Tempel, Fernando Martin, Peter Loppnau, Alexander N Plotnikov

J Biol Chem· October 2007

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Structure and mechanism of spermidine synthases.
Hong Wu, Jinrong Min, Yoshihiko Ikeguchi, Hong Zeng, Aiping Dong, Alexander N Plotnikov

Biochemistry· July 2007

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Structural and chemical profiling of the human cytosolic sulfotransferases.
Abdellah Allali-Hassani, Patricia W Pan, Ludmila Dombrovski, Rafael Najmanovich, Wolfram Tempel, Alexander N Plotnikov

PLoS Biol· May 2007

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