Publications by authors named "Alexander Nielsen"

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Positive 10-year clinical outcomes of a total hip arthroplasty system with a unique femoral stem design.
Alexander Nielsen, Jesua Law, Matthew Parkin, Aaron Hofmann

J Orthop· December 2025

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Positive clinical outcomes at 10 Years with the universal femoral component in total knee arthroplasty.
Alexander Nielsen, Jesua Law, Lauren Homolka, D Alex Forrester, Aaron Hofmann

J Orthop· August 2025

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Bulk Measurement of Membrane Permeability for Random Cyclic Peptides in Living Cells to Guide Drug Development.
Alexander L Nielsen, Christian R O Bartling, Anne Zarda, Nathan De Sadeleer, Rebecca M Neeser

Angew Chem Int Ed Engl· July 2025

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Large Macrocyclic Libraries via Thioether Cyclization.
Alexander L Nielsen

Methods Mol Biol· July 2025

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Discovery of De Novo Macrocycle Inhibitors of Histone Deacetylase 11.
Daniela Danková, Alexander L Nielsen, Anne Zarda, Tobias N Hansen, Marie Hesse

JACS Au· March 2025

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Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation.
Alexander L Nielsen, Zsolt Bognar, Ganesh K Mothukuri, Anne Zarda, Mischa Schüttel

Angew Chem Int Ed Engl· June 2024

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De novo development of small cyclic peptides that are orally bioavailable.
Manuel L Merz, Sevan Habeshian, Bo Li, Jean-Alexandre G L David, Alexander L Nielsen

Nat Chem Biol· May 2024

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Solid-phase peptide synthesis in 384-well plates.
Mischa Schüttel, Edward Will, Gontran Sangouard, Anne Zarda, Sevan Habeshian, Alexander L Nielsen

J Pept Sci· April 2024

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Cyclic Peptides for Drug Development.
Xinjian Ji, Alexander L Nielsen, Christian Heinis

Angew Chem Int Ed Engl· January 2024

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Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide-Activated Sirtuin 7.
Julie E Bolding, Alexander L Nielsen, Iben Jensen, Tobias N Hansen, Line A Ryberg

Angew Chem Int Ed Engl· December 2023

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A bipartite function of ESRRB can integrate signaling over time to balance self-renewal and differentiation.
Teresa E Knudsen, William B Hamilton, Martin Proks, Maria Lykkegaard, Madeleine Linneberg-Agerholm, Alexander V Nielsen

Cell Syst· September 2023

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Transformation of a Metal Chelate into a "Catch and Anchor" Inhibitor of Botulinum A Protease.
Lucy Lin, Ealin N Patel, Alexander L Nielsen, Lewis D Turner, William H Tepp

Int J Mol Sci· February 2023

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A Stereocontrolled Total Synthesis of Lipoxin B4 and its Biological Activity as a Pro-Resolving Lipid Mediator of Neuroinflammation.
C Frank Lee, Carla E Brown, Alexander J Nielsen, Changmo Kim, Izhar Livne-Bar

Chemistry· June 2022

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Identification of the central intermediate in the extra-embryonic to embryonic endoderm transition through single-cell transcriptomics.
Michaela Mrugala Rothová, Alexander Valentin Nielsen, Martin Proks, Yan Fung Wong, Alba Redo Riveiro

Nat Cell Biol· June 2022

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Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme.
Nima Rajabi, Tobias N Hansen, Alexander L Nielsen, Huy T Nguyen, Michael Baek

Angew Chem Int Ed Engl· May 2022

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Understanding Patient Preference of Providers to Treat Foot and Ankle Disorders.
Jonathan Kraus, Alexander Nielsen, Brian Law, Glenn Shi, Gunnar Whealy

Clin Med Res· March 2022

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Chemical Pretreatment Activated a Plastic State Amenable to Direct Lineage Reprogramming.
Zhenghao Yang, Xiaochan Xu, Chan Gu, Alexander Valentin Nielsen, Guokai Chen

Front Cell Dev Biol· March 2022

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Class I histone deacetylases (HDAC1-3) are histone lysine delactylases.
Carlos Moreno-Yruela, Di Zhang, Wei Wei, Michael Bæk, Wenchao Liu, Alexander L Nielsen

Sci Adv· January 2022

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Nonlinear Localization of Dissipative Modulation Instability.
Alexander U Nielsen, Yiqing Xu, Caleb Todd, Michel Ferré, Marcel G Clerc

Phys Rev Lett· September 2021

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Use of Crystallography and Molecular Modeling for the Inhibition of the Botulinum Neurotoxin A Protease.
Lewis D Turner, Alexander L Nielsen, Lucy Lin, Antonio J Campedelli, Nicholas R Silvaggi

ACS Med Chem Lett· August 2021

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Spontaneous symmetry breaking of dissipative optical solitons in a two-component Kerr resonator.
Gang Xu, Alexander U Nielsen, Bruno Garbin, Lewis Hill, Gian-Luca Oppo

Nat Commun· June 2021

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Irreversible inhibition of BoNT/A protease: proximity-driven reactivity contingent upon a bifunctional approach.
Lewis D Turner, Alexander L Nielsen, Lucy Lin, Sabine Pellett, Takashi Sugane

RSC Med Chem· June 2021

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Mechanism-based inhibitors of SIRT2: structure-activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration.
Alexander L Nielsen, Nima Rajabi, Norio Kudo, Kathrine Lundø, Carlos Moreno-Yruela

RSC Chem Biol· April 2021

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Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase.
Kathrin S Troelsen, Michael Bæk, Alexander L Nielsen, Andreas S Madsen, Nima Rajabi

RSC Chem Biol· April 2021

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