Publications by authors named "Alexander Silver"

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Clonal hematopoiesis activates procalcific pathways in macrophages and promotes aortic valve stenosis.
Wesley T Abplanalp, Michael A Raddatz, Bianca Schuhmacher, Silvia Mas-Peiro, María A Zuriaga, Alexander J Silver

J Clin Invest· January 2026

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Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-related Patterns and Relies on IL1RAP for Clonal Expansion.
Divij Verma, Rachel Zeig-Owens, David G Goldfarb, Leah Kravets, Kith Pradhan, Alexander J Silver

Cancer Discov· December 2025

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Seronegative Paraneoplastic Opsoclonus-Myoclonus-Ataxia Syndrome Secondary to Low Volume Endocrine-Sensitive Malignancy of Likely Breast Origin.
Geraint Berger, Caitlin Jackson-Tarlton, Daniel Rayson, Alexander Silver, Mark Walsh

Curr Oncol· August 2025

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Interallelic gene conversion of leukemia-associated single nucleotide variants.
Alexander J Silver, Donovan J Brown, Sarah D Olmstead, Jackson M Watke, Agnieszka E Gorska

Gene· July 2025

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Germline genetics, disease, and exposure to medication influence longitudinal dynamics of clonal hematopoiesis.
Taralynn Mack, Yash Pershad, Caitlyn Vlasschaert, Cosmin A Bejan, Jonathan Brett Heimlich, Alexander J Silver

Haematologica· April 2025

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A blueprint for pursuing therapeutic interventions and early phase clinical trials in clonal haematopoiesis.
Tamanna Haque, Aditi Shastri, Pinkal Desai, Zhuoer Xie, Danielle Hammond, Alexander J Silver

Br J Haematol· February 2025

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Overcoming the conversion reaction limitation at three-phase interfaces using mixed conductors towards energy-dense solid-state Li-S batteries.
Daiwei Wang, Bharat Gwalani, Dominik Wierzbicki, Vijay Singh, Li-Ji Jhang, Alexander Silver

Nat Mater· February 2025

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Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies.
Christian T Meyer, Brianna N Smith, Jing Wang, Kevin B Teuscher, Brian C Grieb, Alexander J Silver

Proc Natl Acad Sci U S A· August 2024

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Multiomic profiling of human clonal hematopoiesis reveals genotype and cell-specific inflammatory pathway activation.
J Brett Heimlich, Pawan Bhat, Alyssa C Parker, Matthew T Jenkins, Caitlyn Vlasschaert, Alexander J Silver

Blood Adv· July 2024

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Cost-Effective and Scalable Clonal Hematopoiesis Assay Provides Insight into Clonal Dynamics.
Taralynn Mack, Caitlyn Vlasschaert, Kelly von Beck, Alexander J Silver, J Brett Heimlich

J Mol Diagn· July 2024

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Clonal hematopoiesis and inflammation in the vasculature: CHIVE, a prospective, longitudinal clonal hematopoiesis cohort and biorepository.
Morgan L Shannon, J Brett Heimlich, Sydney Olson, Ariana Debevec, Zachary Copeland, Alexander J Silver

Blood Adv· July 2024

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Solid Organ Transplant Recipients Exhibit More TET2-Mutant Clonal Hematopoiesis of Indeterminate Potential Not Driven by Increased Transplantation Risk.
Alexander J Silver, Caitlyn Vlasschaert, Taralynn Mack, Brian Sharber, Yaomin Xu

Clin Cancer Res· June 2024

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Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia.
Andrew J Monteith, Haley E Ramsey, Alexander J Silver, Donovan Brown, Dalton Greenwood

Cancer Res· April 2024

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Repair of leukemia-associated single nucleotide variants via interallelic gene conversion.
Alexander James Silver, Donovan J Brown, Sarah D Olmstead, Jackson M Watke, Agnieszka E Gorska

bioRxiv· April 2024

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Driver mutation zygosity is a critical factor in predicting clonal hematopoiesis transformation risk.
Ashwin Kishtagari, M A Wasay Khan, Yajing Li, Caitlyn Vlasschaert, Naimisha Marneni, Alexander J Silver

Blood Cancer J· January 2024

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Cost-effective and scalable clonal hematopoiesis assay provides insight into clonal dynamics.
Taralynn Mack, Caitlyn Vlasschaert, Kelly von Beck, Alexander J Silver, J Brett Heimlich

medRxiv· November 2023

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Loss-of-function mutations in Dnmt3a and Tet2 lead to accelerated atherosclerosis and concordant macrophage phenotypes.
Philipp J Rauch, Jayakrishnan Gopakumar, Alexander J Silver, Daniel Nachun, Herra Ahmad

Nat Cardiovasc Res· September 2023

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A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic data sets.
Caitlyn Vlasschaert, Taralynn Mack, J Brett Heimlich, Abhishek Niroula, Md Mesbah Uddin, Alexander J Silver

Blood· May 2023

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Patient-specific comorbidities as prognostic variables for survival in myelofibrosis.
Andrew L Sochacki, Cosmin Adrian Bejan, Shilin Zhao, Ameet Patel, Ashwin Kishtagari, Alexander J Silver

Blood Adv· March 2023

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High burden of clonal hematopoiesis in first responders exposed to the World Trade Center disaster.
Sakshi Jasra, Orsi Giricz, Rachel Zeig-Owens, Kith Pradhan, David G Goldfarb, Alexander J Silver

Nat Med· March 2022

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Predicting Individual Treatment Response to rTMS for Motor Recovery After Stroke: A Review and the CanStim Perspective.
Franziska E Hildesheim, Alexander N Silver, Adan-Ulises Dominguez-Vargas, Justin W Andrushko, Jodi D Edwards

Front Rehabil Sci· February 2022

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Germline risk of clonal haematopoiesis.
Alexander J Silver, Alexander G Bick, Michael R Savona

Nat Rev Genet· September 2021

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Publisher Correction: Germline risk of clonal haematopoiesis.
Alexander J Silver, Alexander G Bick, Michael R Savona

Nat Rev Genet· September 2021

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Clonal hematopoiesis: Pre-cancer PLUS.
Alexander J Silver, Siddhartha Jaiswal

Adv Cancer Res· April 2020

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Chemical and Bio Sensing Using Graphene-Enhanced Raman Spectroscopy.
Alexander Silver, Hikari Kitadai, He Liu, Tomotaroh Granzier-Nakajima, Mauricio Terrones

Nanomaterials (Basel)· April 2019

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