Publications by authors named "Alexander Stoeck"

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Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRAS Inhibitor.
Xiaoshen Ma, David L Sloman, Ruchia Duggal, Kenneth D Anderson, Jeanine E Ballard, Alexander Stoeck

J Med Chem· July 2024

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Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling.
Shuhui Lim, Nicolas Boyer, Nicole Boo, Chunhui Huang, Gireedhar Venkatachalam, Alexander Stoeck

Chem Sci· December 2021

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Discovery and characterization of novel peptide inhibitors of the NRF2/MAFG/DNA ternary complex for the treatment of cancer.
Vladimir Simov, Michael D Altman, Elisabetta Bianchi, Sonia DelRizzo, Edward N DiNunzio, Alexander Stoeck

Eur J Med Chem· November 2021

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De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits.
Simon Ng, Yu-Chi Juang, Arun Chandramohan, Hung Yi Kristal Kaan, Ahmad Sadruddin, Alexander Stoeck

ACS Med Chem Lett· October 2020

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Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry.
Michael J Kluk, Todd Ashworth, Hongfang Wang, Birgit Knoechel, Emily F Mason, Alexander Stoeck

PLoS One· October 2017

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High Levels of Expression of P-glycoprotein/Multidrug Resistance Protein Result in Resistance to Vintafolide.
Amy D Guertin, Jennifer O'Neil, Alexander Stoeck, Joseph A Reddy, Razvan Cristescu

Mol Cancer Ther· August 2016

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Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma.
Alexander Stoeck, Serguei Lejnine, Andrew Truong, Li Pan, Hongfang Wang

Cancer Discov· October 2014

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Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancer.
Jin-Gyoung Jung, Alexander Stoeck, Bin Guan, Ren-Chin Wu, Heng Zhu

PLoS Genet· October 2014

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Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer.
Luca Magnani, Alexander Stoeck, Xiaoyang Zhang, András Lánczky, Anne C Mirabella

Proc Natl Acad Sci U S A· April 2013

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Identification of PBX1 target genes in cancer cells by global mapping of PBX1 binding sites.
Michelle M Thiaville, Alexander Stoeck, Li Chen, Ren-Chin Wu, Luca Magnani

PLoS One· September 2012

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Defining NOTCH3 target genes in ovarian cancer.
Xu Chen, Michelle M Thiaville, Li Chen, Alexander Stoeck, Jianhua Xuan

Cancer Res· May 2012

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Sequential and gamma-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growth.
Alexander Stoeck, Li Shang, Peter J Dempsey

J Cell Sci· July 2010

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Jagged1 expression regulated by Notch3 and Wnt/β-catenin signaling pathways in ovarian cancer.
Xu Chen, Alexander Stoeck, Soo Jung Lee, Ie-Ming Shih, Michael M Wang

Oncotarget· July 2010

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ADAM10 as a target for anti-cancer therapy.
Marcia L Moss, Alexander Stoeck, Wenbo Yan, Peter J Dempsey

Curr Pharm Biotechnol· February 2008

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The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events.
Marcia L Moss, Martha Bomar, Qian Liu, Harvey Sage, Peter Dempsey, Alexander Stoeck

J Biol Chem· December 2007

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Malignant ascites-derived exosomes of ovarian carcinoma patients contain CD24 and EpCAM.
Steffen Runz, Sascha Keller, Christian Rupp, Alexander Stoeck, Yasmin Issa

Gynecol Oncol· December 2007

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L1-CAM in a membrane-bound or soluble form augments protection from apoptosis in ovarian carcinoma cells.
Alexander Stoeck, Daniela Gast, Michael P Sanderson, Yasmin Issa, Paul Gutwein

Gynecol Oncol· February 2007

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Exosomes: from biogenesis and secretion to biological function.
Sascha Keller, Michael P Sanderson, Alexander Stoeck, Peter Altevogt

Immunol Lett· November 2006

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L1 on ovarian carcinoma cells is a binding partner for Neuropilin-1 on mesothelial cells.
Alexander Stoeck, Sabine Schlich, Yasmin Issa, Verena Gschwend, Till Wenger

Cancer Lett· August 2006

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A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44.
Alexander Stoeck, Sascha Keller, Svenja Riedle, Michael P Sanderson, Steffen Runz

Biochem J· February 2006

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L1 augments cell migration and tumor growth but not beta3 integrin expression in ovarian carcinomas.
Daniela Gast, Svenja Riedle, Svenja Riedle, Heidi Schabath, Sabine Schlich, Alexander Stoeck

Int J Cancer· July 2005

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Cleavage of L1 in exosomes and apoptotic membrane vesicles released from ovarian carcinoma cells.
Paul Gutwein, Alexander Stoeck, Svenja Riedle, Daniela Gast, Steffen Runz

Clin Cancer Res· April 2005

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Brain development in mice lacking L1-L1 homophilic adhesion.
Kyoko Itoh, Ling Cheng, Yoshimasa Kamei, Shinji Fushiki, Hiroyuki Kamiguchi, Alexander Stoeck

J Cell Biol· April 2004

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L1 expression as a predictor of progression and survival in patients with uterine and ovarian carcinomas.
Mina Fogel, Paul Gutwein, Sabine Mechtersheimer, Svenja Riedle, Alexander Stoeck

Lancet· September 2003

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ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles.
Paul Gutwein, Sabine Mechtersheimer, Svenja Riedle, Alexander Stoeck, Daniela Gast

FASEB J· February 2003

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