Publications by authors named "Alexander T Dilthey"

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Pangenome-based genome inference using integer programming.
Ghanshyam Chandra, Md Helal Hossen, Stephan Scholz, Alexander T Dilthey, Daniel Gibney

Genome Res· December 2025

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Large-scale SARS-CoV-2 sequencing indicates prior community circulation of the viral strain associated with Germany's largest meat processing plant.
Jessica Nicolai, Abigail J Miller, Naja Hahn, Julia Fazaal, Anne Bunte, Alexander T Dilthey

Sci Rep· November 2025

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Author Correction: Complex genetic variation in nearly complete human genomes.
Glennis A Logsdon, Peter Ebert, Peter A Audano, Mark Loftus, David Porubsky, Alexander T Dilthey

Nature· September 2025

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Complex genetic variation in nearly complete human genomes.
Glennis A Logsdon, Peter Ebert, Peter A Audano, Mark Loftus, David Porubsky, Alexander T Dilthey

Nature· August 2025

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From sequence to activity: the HgaI-homologous restriction modification system RM.MhoVI of Mycoplasma hominis.
Lars Vogelgsang, Manuel Dolgopolow-Schmidt, Azlan Nisar, Dana Bäcker, Alexander T Dilthey

BMC Microbiol· August 2025

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NanoCore: core-genome-based bacterial genomic surveillance and outbreak detection in healthcare facilities from Nanopore and Illumina data.
Sebastian A Fuchs, Lisanna Hülse, Teresa Tamayo, Susanne Kolbe-Busch, Klaus Pfeffer, Alexander T Dilthey

mSystems· November 2024

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Integer programming framework for pangenome-based genome inference.
Ghanshyam Chandra, Md Helal Hossen, Stephan Scholz, Alexander T Dilthey, Daniel Gibney

bioRxiv· October 2024

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Complex genetic variation in nearly complete human genomes.
Glennis A Logsdon, Peter Ebert, Peter A Audano, Mark Loftus, David Porubsky, Alexander T Dilthey

bioRxiv· September 2024

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High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response.
Alexander J Mentzer, Alexander T Dilthey, Martin Pollard, Deepti Gurdasani, Emre Karakoc

Nat Med· May 2024

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HOGVAX: Exploiting epitope overlaps to maximize population coverage in vaccine design with application to SARS-CoV-2.
Sara C Schulte, Alexander T Dilthey, Gunnar W Klau

Cell Syst· December 2023

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Complete sequences of six major histocompatibility complex haplotypes, including all the major MHC class II structures.
Torsten Houwaart, Stephan Scholz, Nicholas R Pollock, William H Palmer, Katherine M Kichula, Alexander T Dilthey

HLA· July 2023

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Rapid Selection of Sotrovimab Escape Variants in Severe Acute Respiratory Syndrome Coronavirus 2 Omicron-Infected Immunocompromised Patients.
Smaranda Gliga, Nadine Lübke, Alexander Killer, Henning Gruell, Andreas Walker, Alexander T Dilthey

Clin Infect Dis· February 2023

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Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021.
Torsten Houwaart, Samir Belhaj, Emran Tawalbeh, Dirk Nagels, Yara Fröhlich, Alexander T Dilthey

Euro Surveill· October 2022

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Pangenome-based genome inference allows efficient and accurate genotyping across a wide spectrum of variant classes.
Jana Ebler, Peter Ebert, Wayne E Clarke, Tobias Rausch, Peter A Audano, Alexander T Dilthey

Nat Genet· April 2022

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Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Clusters Based on Integrated Genomic Surveillance, Outbreak Analysis and Contact Tracing in an Urban Setting.
Andreas Walker, Torsten Houwaart, Patrick Finzer, Lutz Ehlkes, Alona Tyshaieva, Alexander T Dilthey

Clin Infect Dis· March 2022

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Modifying splice site usage with : Maintaining the while changing the underlying .
Johannes Ptok, Lisa Müller, Philipp Niklas Ostermann, Anastasia Ritchie, Alexander T Dilthey

Comput Struct Biotechnol J· May 2021

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State-of-the-art genome inference in the human MHC.
Alexander T Dilthey

Int J Biochem Cell Biol· February 2021

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Characterisation of mobile genetic elements in Mycoplasma hominis with the description of ICEHo-II, a variant mycoplasma integrative and conjugative element.
Birgit Henrich, Stephanie Hammerlage, Sebastian Scharf, Diana Haberhausen, Ursula Fürnkranz, Alexander T Dilthey

Mob DNA· November 2020

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A diploid assembly-based benchmark for variants in the major histocompatibility complex.
Chen-Shan Chin, Justin Wagner, Qiandong Zeng, Erik Garrison, Shilpa Garg, Alexander T Dilthey

Nat Commun· September 2020

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Development and validation of a universal blood donor genotyping platform: a multinational prospective study.
Nicholas S Gleadall, Barbera Veldhuisen, Jeremy Gollub, Adam S Butterworth, John Ord, Alexander T Dilthey

Blood Adv· August 2020

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Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections.
Neneh Sallah, Wendell Miley, Nazzarena Labo, Tommy Carstensen, Segun Fatumo, Alexander T Dilthey

Nat Commun· July 2020

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Genetic structure of SARS-CoV-2 reflects clonal superspreading and multiple independent introduction events, North-Rhine Westphalia, Germany, February and March 2020.
Andreas Walker, Torsten Houwaart, Tobias Wienemann, Malte Kohns Vasconcelos, Daniel Strelow, Alexander T Dilthey

Euro Surveill· June 2020

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Ultraplexing: increasing the efficiency of long-read sequencing for hybrid assembly with k-mer-based multiplexing.
Alexander T Dilthey, Sebastian A Meyer, Achim J Kaasch

Genome Biol· March 2020

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Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk.
Katarina Tengvall, Jesse Huang, Cecilia Hellström, Patrick Kammer, Martin Biström, Alexander T Dilthey

Proc Natl Acad Sci U S A· August 2019

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Strain-level metagenomic assignment and compositional estimation for long reads with MetaMaps.
Alexander T Dilthey, Chirag Jain, Sergey Koren, Adam M Phillippy

Nat Commun· July 2019

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