Publications by authors named "Alexander U Singer"

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An asymmetric tetrabody is a potent and efficacious agonist of the erythropoietin receptor in vitro and in vivo.
Jarrett J Adams, Levi L Blazer, Jacky Chung, Minoo Karimi, Taylor Davidson, Alexander U Singer

Protein Sci· October 2025

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Synthetic antibodies targeting EphA2 induce diverse signaling-competent clusters with differential activation.
Jarrett J Adams, Heather A Bruce, Suryasree Subramania, Lynda Ploder, Julia Garcia, Alexander U Singer

Protein Sci· June 2025

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Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones.
Heather A Bruce, Alexander U Singer, Levi L Blazer, Khanh Luu, Lynda Ploder

Protein Sci· July 2024

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Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Heather A Bruce, Alexander U Singer, Ekaterina V Filippova, Levi L Blazer, Jarrett J Adams

Protein Sci· January 2024

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A pathogen type III effector with a novel E3 ubiquitin ligase architecture.
Alexander U Singer, Sebastian Schulze, Tatiana Skarina, Xiaohui Xu, Hong Cui

PLoS Pathog· January 2013

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Structure and activity of the cold-active and anion-activated carboxyl esterase OLEI01171 from the oil-degrading marine bacterium Oleispira antarctica.
Sofia Lemak, Anatoli Tchigvintsev, Pierre Petit, Robert Flick, Alexander U Singer

Biochem J· July 2012

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Phage auxiliary metabolic genes and the redirection of cyanobacterial host carbon metabolism.
Luke R Thompson, Qinglu Zeng, Libusha Kelly, Katherine H Huang, Alexander U Singer

Proc Natl Acad Sci U S A· September 2011

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Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme.
Anatoli Tchigvintsev, Alexander U Singer, Robert Flick, Pierre Petit, Greg Brown

Biochem J· July 2011

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NleG Type 3 effectors from enterohaemorrhagic Escherichia coli are U-Box E3 ubiquitin ligases.
Bin Wu, Tatiana Skarina, Adelinda Yee, Marie-Claude Jobin, Rosa Dileo, Alexander U Singer

PLoS Pathog· June 2010

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Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases.
Alexander U Singer, John R Rohde, Robert Lam, Tatiana Skarina, Olga Kagan

Nat Struct Mol Biol· December 2008

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