Publications by authors named "Alexandra Nicholson"

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The role of neurofilament light in genetic frontotemporal lobar degeneration.
Henrik Zetterberg, Charlotte Teunissen, John van Swieten, Jens Kuhle, Adam Boxer, Alexandra M Nicholson

Brain Commun· November 2022

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Loss of Tmem106b leads to cerebellum Purkinje cell death and motor deficits.
Rosa Rademakers, Alexandra M Nicholson, Yingxue Ren, Shunsuke Koga, Hung Phuoc Nguyen

Brain Pathol· May 2021

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Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies.
Xiaolai Zhou, Alexandra M Nicholson, Yingxue Ren, Mieu Brooks, Peizhou Jiang

Brain· June 2020

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Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency.
Andrew E Arrant, Alexandra M Nicholson, Xiaolai Zhou, Rosa Rademakers, Erik D Roberson

Mol Neurodegener· June 2018

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Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity.
Alexandra M Nicholson, Xiaolai Zhou, Ralph B Perkerson, Tammee M Parsons, Jeannie Chew

Acta Neuropathol Commun· May 2018

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Assessing changes in HIV-related legal and policy environments: Lessons learned from a multi-country evaluation.
Laura Ferguson, Alexandra Nicholson, Ian Henry, Amitrajit Saha, Tilly Sellers

PLoS One· April 2018

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Clinical and neuropathological features of ALS/FTD with TIA1 mutations.
Veronica Hirsch-Reinshagen, Cyril Pottier, Alexandra M Nicholson, Matt Baker, Ging-Yuek R Hsiung

Acta Neuropathol Commun· December 2017

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A novel methodology for strengthening human rights based monitoring in public health: Family planning indicators as an illustrative example.
Sofia Gruskin, Laura Ferguson, Shubha Kumar, Alexandra Nicholson, Moazzam Ali

PLoS One· December 2017

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Abnormal expression of homeobox genes and transthyretin in expansion carriers.
NiCole A Finch, Xue Wang, Matthew C Baker, Michael G Heckman, Tania F Gendron, Alexandra M Nicholson

Neurol Genet· August 2017

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TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics.
Ian R Mackenzie, Alexandra M Nicholson, Mohona Sarkar, James Messing, Maria D Purice

Neuron· August 2017

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Development of a single, practical measure of surgical site infection (SSI) for patient report or observer completion.
Rhiannon C Macefield, Barnaby C Reeves, Thomas K Milne, Alexandra Nicholson, Natalie S Blencowe

J Infect Prev· July 2017

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Soluble sortilin is present in excess and positively correlates with progranulin in CSF of aging individuals.
Simon Molgaard, Ditte Demontis, Alexandra M Nicholson, Nicole A Finch, Ronald C Petersen

Exp Gerontol· November 2016

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What we know about TMEM106B in neurodegeneration.
Alexandra M Nicholson, Rosa Rademakers

Acta Neuropathol· November 2016

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Prosaposin is a regulator of progranulin levels and oligomerization.
Alexandra M Nicholson, NiCole A Finch, Marcio Almeida, Ralph B Perkerson, Marka van Blitterswijk

Nat Commun· June 2016

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Effectiveness of hand hygiene interventions in reducing illness absence among children in educational settings: a systematic review and meta-analysis.
Micky Willmott, Alexandra Nicholson, Heide Busse, Georgina J MacArthur, Sara Brookes

Arch Dis Child· January 2016

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The TMEM106B locus and TDP-43 pathology in older persons without FTLD.
Dennis W Dickson, Rosa Rademakers, Alexandra M Nicholson, Julie A Schneider, Lei Yu

Neurology· October 2015

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Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease.
Cyril Pottier, Kevin F Bieniek, NiCole Finch, Maartje van de Vorst, Matt Baker, Alexandra M Nicholson

Acta Neuropathol· July 2015

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Genetic screening and functional characterization of PDGFRB mutations associated with basal ganglia calcification of unknown etiology.
Monica Sanchez-Contreras, Matthew C Baker, NiCole A Finch, Alexandra Nicholson, Aleksandra Wojtas

Hum Mutat· August 2014

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Progranulin protein levels are differently regulated in plasma and CSF.
Alexandra M Nicholson, NiCole A Finch, Colleen S Thomas, Aleksandra Wojtas, Nicola J Rutherford

Neurology· May 2014

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TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia.
Marka van Blitterswijk, Bianca Mullen, Alexandra M Nicholson, Kevin F Bieniek, Michael G Heckman

Acta Neuropathol· March 2014

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Parkinsonian features in hereditary diffuse leukoencephalopathy with spheroids (HDLS) and CSF1R mutations.
Christina Sundal, Shinsuke Fujioka, Jay A Van Gerpen, Christian Wider, Alexandra M Nicholson

Parkinsonism Relat Disord· October 2013

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TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia.
Alexandra M Nicholson, Nicole A Finch, Aleksandra Wojtas, Matt C Baker, Ralph B Perkerson

J Neurochem· September 2013

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Implementation of an educational intervention to improve hand washing in primary schools: process evaluation within a randomised controlled trial.
Catherine R Chittleborough, Alexandra L Nicholson, Elaine Young, Sarah Bell, Rona Campbell

BMC Public Health· August 2013

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CSF1R mutations link POLD and HDLS as a single disease entity.
Alexandra M Nicholson, Matt C Baker, Nicole A Finch, Nicola J Rutherford, Christian Wider

Neurology· March 2013

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