Publications by authors named "Alexandre Kauskot"

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Unveiling platelet aging with progressive β-galactose exposure as a signature of platelet senescence in humans and mice.
Catherine Angénieux, Thomas Nipoti, Gabriel Rojas-Jiménez, Mélanie Daniel, Frédéric Adam, Alexandre Kauskot

Haematologica· December 2025

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F-actin disassembly by the oxidoreductase MICAL1 promotes mechano-dependent VWF-GPIbα interaction in platelets.
Jean Solarz, Christelle Soukaseum, Stéphane Frémont, Sébastien Eymieux, Camilia Nabli, Alexandre Kauskot

Nat Commun· August 2025

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Increased RhoA pathway activation downstream of αIIbβ3/SRC contributes to heterozygous Bernard Soulier syndrome.
Larissa Lordier, Christian A Di Buduo, Alexandre Kauskot, Nathalie Balayn, Cécile Lavenu-Bombled

Haematologica· July 2025

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Consensus protocol for platelet desialylation (β-galactose exposure) quantification using lectins by flow cytometry: communication from the ISTH SSC Subcommittee on Platelet Physiology.
Alexandre Kauskot, Sofia Ramstrom, Thomas Nipoti, Dianne E van der Wal

J Thromb Haemost· June 2025

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Thrombin cleaves membrane-bound endoglin potentially contributing to the heterogeneity of circulating endoglin in preeclampsia.
Divina El Hamaoui, Aurore Marchelli, Sophie Gandrille, Etienne Reboul, Alain Stepanian, Alexandre Kauskot

Commun Biol· February 2025

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Somatic RAP1B gain-of-function variant underlies isolated thrombocytopenia and immunodeficiency.
Marta Benavides-Nieto, Frédéric Adam, Emmanuel Martin, Charlotte Boussard, Chantal Lagresle-Peyrou, Alexandre Kauskot

J Clin Invest· July 2024

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Deregulation of the p19/CDK4/CDK6 axis in Jak2 megakaryocytes accelerates the development of myelofibrosis.
Hélène Duparc, Delphine Muller, Laure Gilles, Agathe L Chédeville, Mira El Khoury, Alexandre Kauskot

Leukemia· April 2024

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MAGT1 deficiency in XMEN disease is associated with severe platelet dysfunction and impaired platelet glycoprotein N-glycosylation.
Alexandre Kauskot, Coralie Mallebranche, Arnaud Bruneel, François Fenaille, Jean Solarz

J Thromb Haemost· November 2023

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Over-expression of Dyrk1A affects bleeding by modulating plasma fibronectin and fibrinogen level in mice.
Guillaume Postic, Jean Solarz, Cécile Loubière, Janany Kandiah, Jaysen Sawmynaden, Alexandre Kauskot

J Cell Mol Med· August 2023

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Soluble endoglin reduces thrombus formation and platelet aggregation via interaction with αIIbβ3 integrin.
Elisa Rossi, Miguel Pericacho, Alexandre Kauskot, Luis Gamella-Pozuelo, Etienne Reboul

J Thromb Haemost· July 2023

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DOCK11 deficiency in patients with X-linked actinopathy and autoimmunity.
Charlotte Boussard, Laure Delage, Tania Gajardo, Alexandre Kauskot, Maxime Batignes

Blood· June 2023

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ADP receptor P2Y12 is the capstone of the cross-talk between Ca mobilization pathways dependent on Ca ATPases sarcoplasmic/endoplasmic reticulum type 3 and type 2b in platelets.
Miao Feng, Béatrice Hechler, Frédéric Adam, Christian Gachet, Anita Eckly, Alexandre Kauskot

Res Pract Thromb Haemost· January 2023

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A gain-of-function filamin A mutation in mouse platelets induces thrombus instability.
Frédéric Adam, Alexandre Kauskot, Lamia Lamrani, Jean Solarz, Christelle Soukaseum

J Thromb Haemost· November 2022

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A thrombopoietin receptor agonist to rescue an unusual platelet transfusion-induced reaction in a p.V1316M-associated von Willebrand disease type 2B patient.
Caterina Casari, Remi Favier, Paulette Legendre, Alexandre Kauskot, Frederic Adam

Ther Adv Hematol· February 2022

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Endoglin Is an Endothelial Housekeeper against Inflammation: Insight in ECFC-Related Permeability through LIMK/Cofilin Pathway.
Elisa Rossi, Alexandre Kauskot, François Saller, Elisa Frezza, Sonia Poirault-Chassac

Int J Mol Sci· August 2021

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Mitochondrial dynamics and reactive oxygen species initiate thrombopoiesis from mature megakaryocytes.
Sonia Poirault-Chassac, Valérie Nivet-Antoine, Amandine Houvert, Alexandre Kauskot, Evelyne Lauret

Blood Adv· March 2021

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Towards the Therapeutic Use of Thrombospondin 1/CD47 Targeting TAX2 Peptide as an Antithrombotic Agent.
Albin Jeanne, Thomas Sarazin, Magalie Charlé, Charlotte Kawecki, Alexandre Kauskot

Arterioscler Thromb Vasc Biol· January 2021

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Receptor for Advanced Glycation End Products is Involved in Platelet Hyperactivation and Arterial Thrombosis during Chronic Kidney Disease.
Jérémy Ortillon, Nathalie Hézard, Karim Belmokhtar, Charlotte Kawecki, Christine Terryn, Alexandre Kauskot

Thromb Haemost· September 2020

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A hemophilia A mouse model for the in vivo assessment of emicizumab function.
Stephen Ferrière, Ivan Peyron, Olivier D Christophe, Charlotte Kawecki, Caterina Casari, Alexandre Kauskot

Blood· August 2020

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Measuring beta-galactose exposure on platelets: Standardization and healthy reference values.
Dominique Lasne, Tiffany Pascreau, Sadyo Darame, Marie-Charlotte Bourrienne, Peggy Tournoux, Alexandre Kauskot

Res Pract Thromb Haemost· July 2020

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Relevance of platelet desialylation and thrombocytopenia in type 2B von Willebrand disease: preclinical and clinical evidence.
Annabelle Dupont, Christelle Soukaseum, Mathilde Cheptou, Frédéric Adam, Thomas Nipoti, Alexandre Kauskot

Haematologica· December 2019

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A single-domain antibody that blocks factor VIIa activity in the absence but not presence of tissue factor.
Stephen Ferrière, Charlotte Kawecki, Jean-François Ottavi, Cécile V Denis, Alexandre Kauskot

J Thromb Haemost· December 2019

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A novel missense mutation in a leucine-rich repeat of GPIbα in a Bernard-Soulier variant reduces shear-dependent adherence on von Willebrand factor.
Valerie Proulle, Catherine Strassel, Christelle Perrault, Marie-Jeanne Baas, Sylvie Moog, Alexandre Kauskot

Br J Haematol· September 2019

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TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology.
Athanasia Stoupa, Frédéric Adam, Dulanjalee Kariyawasam, Catherine Strassel, Sanjay Gawade, Alexandre Kauskot

EMBO Mol Med· December 2018

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A mutation of the human gene leads to a major platelet functional defect.
Eliane Berrou, Christelle Soukaseum, Rémi Favier, Frédéric Adam, Ziane Elaib, Alexandre Kauskot

Blood· November 2018

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