Publications by authors named "Alexandre Marechal"

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Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress.
Maxime Galloy, Andréanne Blondeau, Élodie Vion, Daein Kim, Collin A Bakker

Mol Cell· August 2025

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The function of MYC in base excision repair protects against RAS-induced senescence.
Camila C F Faraco, Wanting Zhu, Anne-Marie Fortier, Zubaidah M Ramdzan, Elise Vickridge

Nucleic Acids Res· July 2025

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Detection of γ-H2A.X for Rapid Assessment of Genotoxic Agent-induced Double-strand DNA Breaks by Immunofluorescence.
Billel Djerir, Alexandre Maréchal

Methods Mol Biol· April 2025

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The single-stranded DNA-binding factor SUB1/PC4 alleviates replication stress at telomeres and is a vulnerability of ALT cancer cells.
Jean-Christophe Dubois, Erin Bonnell, Amélie Filion, Julie Frion, Samuel Zimmer

Proc Natl Acad Sci U S A· January 2025

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Heterozygous variant as a novel genetic cause of telomere biology disorders.
Rima Kochman, Ibrahima Ba, Maïlyn Yates, Vithura Pirabakaran, Florian Gourmelon

Genes Dev· September 2024

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An E3 ubiquitin ligase localization screen uncovers DTX2 as a novel ADP-ribosylation-dependent regulator of DNA double-strand break repair.
Billel Djerir, Isabelle Marois, Jean-Christophe Dubois, Steven Findlay, Théo Morin

J Biol Chem· August 2024

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SMARCAL1 ubiquitylation controls its association with RPA-coated ssDNA and promotes replication fork stability.
Maïlyn Yates, Isabelle Marois, Edlie St-Hilaire, Daryl A Ronato, Billel Djerir

PLoS Biol· March 2024

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The function of BCL11B in base excision repair contributes to its dual role as an oncogene and a haplo-insufficient tumor suppressor gene.
Elise Vickridge, Camila C F Faraco, Fanny Lo, Hedyeh Rahimian, Zi Yang Liu

Nucleic Acids Res· January 2024

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Differential effects of pesticides on dioxin receptor signaling and p53 activation.
Myriam Fauteux, Nadia Côté, Sandra Bergeron, Alexandre Maréchal, Luc Gaudreau

Sci Rep· December 2023

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Chronic treatment with ATR and CHK1 inhibitors does not substantially increase the mutational burden of human cells.
Lisa Casimir, Samuel Zimmer, Félix Racine-Brassard, Félix Goudreau, Pierre-Étienne Jacques

Mutat Res· November 2023

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The mutational impact of Illudin S on human cells.
Lisa Casimir, Samuel Zimmer, Félix Racine-Brassard, Pierre-Étienne Jacques, Alexandre Maréchal

DNA Repair (Amst)· February 2023

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The PRP19 Ubiquitin Ligase, Standing at the Cross-Roads of mRNA Processing and Genome Stability.
Mouhamed Idrissou, Alexandre Maréchal

Cancers (Basel)· February 2022

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POGZ promotes homology-directed DNA repair in an HP1-dependent manner.
John Heath, Estelle Simo Cheyou, Steven Findlay, Vincent M Luo, Edgar Pinedo Carpio

EMBO Rep· January 2022

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CUT Domains Stimulate Pol β Enzymatic Activities to Accelerate Completion of Base Excision Repair.
Zubaidah M Ramdzan, Elise Vickridge, Li Li, Camila C F Faraco, Billel Djerir

J Mol Biol· February 2021

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Human high-density lipoprotein microtranscriptome is unique and suggests an extended role in lipid metabolism.
Véronique Desgagné, Renée Guérin, Simon-Pierre Guay, Marjorie Boyer, Elizabeth Hutchins

Epigenomics· June 2019

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SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.
Steven Findlay, John Heath, Vincent M Luo, Abba Malina, Théo Morin

EMBO J· September 2018

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Cellular Depletion of BRD8 Causes p53-Dependent Apoptosis and Induces a DNA Damage Response in Non-Stressed Cells.
Anahita Lashgari, Myriam Fauteux, Alexandre Maréchal, Luc Gaudreau

Sci Rep· September 2018

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Ubiquitylation at the Fork: Making and Breaking Chains to Complete DNA Replication.
Maïlyn Yates, Alexandre Maréchal

Int J Mol Sci· September 2018

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Investigation of Protein Recruitment to DNA Lesions Using 405 Nm Laser Micro-irradiation.
Antoine Gaudreau-Lapierre, Daniel Garneau, Billel Djerir, Frédéric Coulombe, Théo Morin, Alexandre Marechal

J Vis Exp· March 2018

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A phosphorylation-and-ubiquitylation circuitry driving ATR activation and homologous recombination.
Jean-Christophe Dubois, Maïlyn Yates, Antoine Gaudreau-Lapierre, Geneviève Clément, Laurent Cappadocia

Nucleic Acids Res· September 2017

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A LARGe surprise links ATR and Rho.
Alexandre Maréchal, Lee Zou

Cell Cycle· June 2016

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SMARCAL1 Resolves Replication Stress at ALT Telomeres.
Kelli E Cox, Alexandre Maréchal, Rachel Litman Flynn

Cell Rep· February 2016

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RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response.
Alexandre Maréchal, Lee Zou

Cell Res· January 2015

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SUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathway.
Ching-Shyi Wu, Jian Ouyang, Eiichiro Mori, Hai Dang Nguyen, Alexandre Maréchal

Genes Dev· July 2014

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PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.
Alexandre Maréchal, Ju-Mei Li, Xiao Ye Ji, Ching-Shyi Wu, Stephanie A Yazinski

Mol Cell· January 2014

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