Publications by authors named "Alexandre Sostelly"

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Safety, pharmacokinetics, and pharmacodynamics of the antisense oligonucleotide RO7239958 in healthy volunteers and adults with chronic hepatitis B infection.
Anna Maria Geretti, Alexandre Sostelly, Simon Buatois, Sijie Lu, Annabelle Lemenuel

Antimicrob Agents Chemother· December 2025

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Efficacy and safety of the C5 inhibitor crovalimab in complement inhibitor-naive patients with PNH (COMMODORE 3): A multicenter, Phase 3, single-arm study.
Hui Liu, Linghui Xia, Jianyu Weng, Fengkui Zhang, Chuan He, Alexandre Sostelly

Am J Hematol· September 2023

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Crovalimab treatment in patients with paroxysmal nocturnal haemoglobinuria: Long-term results from the phase I/II COMPOSER trial.
Alexander Röth, Satoshi Ichikawa, Yoshikazu Ito, Jin Seok Kim, Zsolt Nagy, Alexandre Sostelly

Eur J Haematol· August 2023

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Mitigating Drug-Target-Drug Complexes in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Switch C5 Inhibitors.
Jun-Ichi Nishimura, Antoine Soubret, Noriko Arase, Simon Buatois, Masaki Hotta, Alexandre Sostelly

Clin Pharmacol Ther· April 2023

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Crovalimab for treatment of patients with paroxysmal nocturnal haemoglobinuria and complement C5 polymorphism: Subanalysis of the phase 1/2 COMPOSER study.
Jun-Ichi Nishimura, Kensuke Usuki, Julia Ramos, Satoshi Ichikawa, Muriel Buri, Alexandre Sostelly

Br J Haematol· August 2022

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Exposure driven dose escalation design with overdose control: Concept and first real life experience in an oncology phase I trial.
Sandrine Micallef, Alexandre Sostelly, Jiawen Zhu, Paul G Baverel, Francois Mercier

Contemp Clin Trials Commun· April 2022

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The complement C5 inhibitor crovalimab in paroxysmal nocturnal hemoglobinuria.
Alexander Röth, Jun-Ichi Nishimura, Zsolt Nagy, Julia Gaàl-Weisinger, Jens Panse, Alexandre Sostelly

Blood· March 2020

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Tumor Size and Overall Survival in Patients With Platinum-Resistant Ovarian Cancer Treated With Chemotherapy and Bevacizumab.
Alexandre Sostelly, François Mercier

Clin Med Insights Oncol· May 2019

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Tumor Static Concentration Curves in Combination Therapy.
Tim Cardilin, Joachim Almquist, Mats Jirstrand, Alexandre Sostelly, Christiane Amendt

AAPS J· March 2017

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Quantitative evaluation of the combination between cytotoxic drug and efflux transporter inhibitors based on a tumour growth inhibition model.
Alexandre Sostelly, Léa Payen, Jérôme Guitton, Attilio Di Pietro, Pierre Falson

Fundam Clin Pharmacol· April 2014

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A template model for studying anticancer drug efflux transporter inhibitors in vitro.
Alexandre Sostelly, Léa Payen, Jérôme Guitton, Attilio Di Pietro, Pierre Falson

Fundam Clin Pharmacol· October 2013

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Can we predict chemo-induced hematotoxicity in elderly patients treated with pegylated liposomal doxorubicin? Results of a population-based model derived from the DOGMES phase II trial of the GINECO.
Alexandre Sostelly, Emilie Henin, Laure Chauvenet, Anne-Claire Hardy-Bessard, Véronique Jestin-Le Tallec

J Geriatr Oncol· January 2013

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