Publications by authors named "Alexandre Trottier"

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Pharmacokinetic profile of PBRM in rodents, a first selective covalent inhibitor of 17β-HSD1 for breast cancer and endometriosis treatments.
René Maltais, Alexandre Trottier, Jenny Roy, Diana Ayan, Nicolas Bertrand

J Steroid Biochem Mol Biol· April 2018

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Insight into the mode of action and selectivity of PBRM, a covalent steroidal inhibitor of 17β-hydroxysteroid dehydrogenase type 1.
Alexandre Trottier, René Maltais, Diana Ayan, Xavier Barbeau, Jenny Roy

Biochem Pharmacol· November 2017

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Impact of structural modifications at positions 13, 16 and 17 of 16β-(m-carbamoylbenzyl)-estradiol on 17β-hydroxysteroid dehydrogenase type 1 inhibition and estrogenic activity.
René Maltais, Alexandre Trottier, Xavier Barbeau, Patrick Lagüe, Martin Perreault

J Steroid Biochem Mol Biol· July 2016

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Identification of fused 16β,17β-oxazinone-estradiol derivatives as a new family of non-estrogenic 17β-hydroxysteroid dehydrogenase type 1 inhibitors.
René Maltais, Alexandre Trottier, Audrey Delhomme, Xavier Barbeau, Patrick Lagüe

Eur J Med Chem· March 2015

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Identification of a first enzymatic activator of a 17β-hydroxysteroid dehydrogenase.
Alexandre Trottier, René Maltais, Donald Poirier

ACS Chem Biol· August 2014

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Discovery of a non-estrogenic irreversible inhibitor of 17β-hydroxysteroid dehydrogenase type 1 from 3-substituted-16β-(m-carbamoylbenzyl)-estradiol derivatives.
René Maltais, Diana Ayan, Alexandre Trottier, Xavier Barbeau, Patrick Lagüe

J Med Chem· January 2014

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Facile photoinduced charge separation through a cyanoacetylide bridge in a heterobimetallic Fe(II)-Re(I) complex.
Mark E Smith, Emma L Flynn, Mark A Fox, Alexandre Trottier, Eckart Wrede

Chem Commun (Camb)· November 2008

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On the dynamics of the H+ +D2(v=0,j=0)-->HD+D + reaction: a comparison between theory and experiment.
Estela Carmona-Novillo, Tomás González-Lezana, Octavio Roncero, Pascal Honvault, Jean-Michel Launay, Alexandre Trottier

J Chem Phys· January 2008

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