Publications by authors named "Alexsandra Espejo"

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Investigative needle core biopsies support multimodal deep-data generation in glioblastoma.
Kenny K H Yu, Sreyashi Basu, Gerard Baquer, Ryuhjin Ahn, Jennifer Gantchev, Alexsandra B Espejo

Nat Commun· April 2025

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Immune checkpoint inhibitors plus debulking surgery for patients with metastatic renal cell carcinoma: clinical outcomes and immunological correlates of a prospective pilot trial.
Sangeeta Goswami, Jianjun Gao, Sreyashi Basu, Daniel D Shapiro, Jose A Karam, Alexsandra B Espejo

Nat Commun· February 2025

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Safety outcomes and immunological correlates in a prospective clinical trial of immune checkpoint therapy plus debulking surgery for patients with metastatic renal cell carcinoma.
Sangeeta Goswami, Jianjun Gao, Sreyashi Basu, Daniel D Shapiro, Jose A Karam, Alexsandra B Espejo

Res Sq· November 2024

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Investigative needle core biopsies for multi-omics in Glioblastoma.
Kenny K H Yu, Sreyashi Basu, Gerard Baquer, Ryuhjin Ahn, Jennifer Gantchev, Alexsandra B Espejo

medRxiv· December 2023

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Comparison of pharmacological inhibitors of lysine-specific demethylase 1 in glioblastoma stem cells reveals inhibitor-specific efficacy profiles.
Lea M Stitzlein, Achintyan Gangadharan, Leslie M Walsh, Deokhwa Nam, Alexsandra B Espejo

Front Neurol· April 2023

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Immune and pathologic responses in patients with localized prostate cancer who received daratumumab (anti-CD38) or edicotinib (CSF-1R inhibitor).
Bilal A Siddiqui, Brian F Chapin, Sonali Jindal, Fei Duan, Sreyashi Basu, Alexsandra B Espejo

J Immunother Cancer· March 2023

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Pilot study of Tremelimumab with and without cryoablation in patients with metastatic renal cell carcinoma.
Matthew T Campbell, Surena F Matin, Alda L Tam, Rahul A Sheth, Kamran Ahrar, Alexsandra B Espejo

Nat Commun· November 2021

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Phosphorylation of Connexin36 near the C-terminus switches binding affinities for PDZ-domain and 14-3-3 proteins in vitro.
Stephan Tetenborg, Helen Y Wang, Lena Nemitz, Anne Depping, Alexsandra B Espejo

Sci Rep· October 2020

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Zdhhc13-dependent Drp1 S-palmitoylation impacts brain bioenergetics, anxiety, coordination and motor skills.
Eleonora Napoli, Gyu Song, Siming Liu, Alexsandra Espejo, Carlos J Perez

Sci Rep· October 2017

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PRMT5 C-terminal Phosphorylation Modulates a 14-3-3/PDZ Interaction Switch.
Alexsandra B Espejo, Guozhen Gao, Karynne Black, Sitaram Gayatri, Nicolas Veland

J Biol Chem· February 2017

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Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation.
Eric Metzger, Dominica Willmann, Joel McMillan, Ignasi Forne, Philipp Metzger, Alexsandra Espejo

Nat Struct Mol Biol· February 2016

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Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 Gene.
Carlos J Perez, Lars Mecklenburg, Jean Jaubert, Lucia Martinez-Santamaria, Brian M Iritani, Alexsandra Espejo

J Invest Dermatol· December 2015

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Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and Its Substrate RNA Splicing Factor SF3B2.
Andrea Hadjikyriacou, Yanzhong Yang, Alexsandra Espejo, Mark T Bedford, Steven G Clarke

J Biol Chem· July 2015

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Phosphorylation-Dependent Enhancement of Rad53 Kinase Activity through the INO80 Chromatin Remodeling Complex.
Prabodh Kapoor, Yunhe Bao, Jing Xiao, Alexsandra Espejo, Lin Yang

Mol Cell· June 2015

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Methyllysine reader plant homeodomain (PHD) finger protein 20-like 1 (PHF20L1) antagonizes DNA (cytosine-5) methyltransferase 1 (DNMT1) proteasomal degradation.
Pierre-Olivier Estève, Jolyon Terragni, Kanneganti Deepti, Hang Gyeong Chin, Nan Dai, Alexsandra Espejo

J Biol Chem· March 2014

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Protein arginine methyl transferases-3 and -5 increase cell surface expression of cardiac sodium channel.
Pedro Beltran-Alvarez, Alexsandra Espejo, Ralf Schmauder, Carlos Beltran, Ralf Mrowka

FEBS Lett· October 2013

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Methylation by Set9 modulates FoxO3 stability and transcriptional activity.
Daniel R Calnan, Ashley E Webb, Jamie L White, Timothy R Stowe, Tapasree Goswami, Alexsandra Espejo

Aging (Albany NY)· July 2012

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Interaction of proliferation cell nuclear antigen (PCNA) with c-Abl in cell proliferation and response to DNA damages in breast cancer.
Huajun Zhao, Po-Chun Ho, Yuan-Hung Lo, Alexsandra Espejo, Mark T Bedford

PLoS One· May 2012

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MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Yanqi Chang, Lidong Sun, Kenji Kokura, John R Horton, Mikiko Fukuda, Alexsandra Espejo

Nat Commun· November 2011

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Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling.
Dan Levy, Alex J Kuo, Yanqi Chang, Uwe Schaefer, Christopher Kitson, Alexsandra Espejo

Nat Immunol· January 2011

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TDRD3 is an effector molecule for arginine-methylated histone marks.
Yanzhong Yang, Yue Lu, Alexsandra Espejo, Jiacai Wu, Wei Xu

Mol Cell· December 2010

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Mouse models for the p53 R72P polymorphism mimic human phenotypes.
Feng Zhu, Martijn E T Dollé, Thomas R Berton, Raoul V Kuiper, Carrie Capps, Alexsandra Espejo

Cancer Res· July 2010

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A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics.
Amy M Quinn, Mark T Bedford, Alexsandra Espejo, Astrid Spannhoff, Christopher P Austin

Nucleic Acids Res· January 2010

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Crystal structure of the three tandem FF domains of the transcription elongation regulator CA150.
Ming Lu, Jun Yang, Zhiyong Ren, Subir Sabui, Alexsandra Espejo

J Mol Biol· October 2009

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Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks.
Dennis J Bua, Alex J Kuo, Peggie Cheung, Chih Long Liu, Valentina Migliori, Alexsandra Espejo

PLoS One· August 2009

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