Publications by authors named "Astrid Spannhoff"

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Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1.
Sabrina Castellano, Astrid Spannhoff, Ciro Milite, Fabrizio Dal Piaz, Donghang Cheng

J Med Chem· November 2012

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Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1.
Elisabeth-Maria Bissinger, Ralf Heinke, Astrid Spannhoff, Adrien Eberlin, Eric Metzger

Bioorg Med Chem· June 2011

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Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees.
Astrid Spannhoff, Yong Kee Kim, Noel J-M Raynal, Vazganush Gharibyan, Ming-Bo Su

EMBO Rep· March 2011

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Borrelidin modulates the alternative splicing of VEGF in favour of anti-angiogenic isoforms.
Jeanette Woolard, William Vousden, Steven J Moss, Arjun Krishnakumar, Melissa Vr Gammons, Astrid Spannhoff

Chem Sci· February 2011

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Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases.
Yanqi Chang, Thota Ganesh, John R Horton, Astrid Spannhoff, Jin Liu

J Mol Biol· July 2010

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Design, synthesis and biological evaluation of carboxy analogues of arginine methyltransferase inhibitor 1 (AMI-1).
Sabrina Castellano, Ciro Milite, Rino Ragno, Silvia Simeoni, Antonello Mai, Astrid Spannhoff

ChemMedChem· March 2010

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A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics.
Amy M Quinn, Mark T Bedford, Alexsandra Espejo, Astrid Spannhoff, Christopher P Austin

Nucleic Acids Res· January 2010

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The emerging therapeutic potential of histone methyltransferase and demethylase inhibitors.
Astrid Spannhoff, Alexander-Thomas Hauser, Ralf Heinke, Wolfgang Sippl, Manfred Jung

ChemMedChem· October 2009

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Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294.
Yanqi Chang, Xing Zhang, John R Horton, Anup K Upadhyay, Astrid Spannhoff

Nat Struct Mol Biol· March 2009

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Cancer treatment of the future: inhibitors of histone methyltransferases.
Astrid Spannhoff, Wolfgang Sippl, Manfred Jung

Int J Biochem Cell Biol· January 2009

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Virtual screening and biological characterization of novel histone arginine methyltransferase PRMT1 inhibitors.
Ralf Heinke, Astrid Spannhoff, Rene Meier, Patrick Trojer, Ingo Bauer

ChemMedChem· January 2009

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A novel arginine methyltransferase inhibitor with cellular activity.
Astrid Spannhoff, Rospita Machmur, Ralf Heinke, Patrick Trojer, Ingo Bauer

Bioorg Med Chem Lett· August 2007

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Target-based approach to inhibitors of histone arginine methyltransferases.
Astrid Spannhoff, Ralf Heinke, Ingo Bauer, Patrick Trojer, Eric Metzger

J Med Chem· May 2007

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