Publications by authors named "Ming-Bo Su"

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Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain.
Teng-Teng Li, Cheng Peng, Ji-Qiu Wang, Zhi-Jian Xu, Ming-Bo Su

Acta Pharmacol Sin· August 2022

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Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma.
Yu-Bo Zhou, Yang-Ming Zhang, Hong-Hui Huang, Li-Jing Shen, Xiao-Feng Han, Ming-Bo Su

Acta Pharmacol Sin· April 2022

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Discovery of a Potent and Selective NF-κB-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo.
Zhiqiang Li, Xinzhi Li, Ming-Bo Su, Li-Xin Gao, Yu-Bo Zhou

J Med Chem· April 2020

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Synthesis and in Vitro and in Vivo Biological Evaluation of Tissue-Specific Bisthiazole Histone Deacetylase (HDAC) Inhibitors.
Shu-Wei Zhang, Chao-Jun Gong, Ming-Bo Su, Fei Chen, Ting He, Yi Su

J Med Chem· January 2020

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Novel spirocyclic tranylcypromine derivatives as lysine-specific demethylase 1 (LSD1) inhibitors.
Ying Shi, Yan-Ran Wu, Ming-Bo Su, Dong-Hao Shen, Hendra Gunosewoyo

RSC Adv· January 2018

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Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors.
Yue-Yang Ji, Sen-Dong Lin, Yu-Jie Wang, Ming-Bo Su, Wei Zhang

Eur J Med Chem· December 2017

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Design, synthesis and biological evaluation of bisthiazole-based trifluoromethyl ketone derivatives as potent HDAC inhibitors with improved cellular efficacy.
Chao-Jun Gong, An-Hui Gao, Yang-Ming Zhang, Ming-Bo Su, Fei Chen

Eur J Med Chem· April 2016

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Curcusone D, a novel ubiquitin-proteasome pathway inhibitor via ROS-induced DUB inhibition, is synergistic with bortezomib against multiple myeloma cell growth.
Mei-Na Cao, Yu-Bo Zhou, An-Hui Gao, Jia-Yi Cao, Li-Xin Gao, Ming-Bo Su

Biochim Biophys Acta· June 2014

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Potent and orally efficacious bisthiazole-based histone deacetylase inhibitors.
Fei Chen, Hui Chai, Ming-Bo Su, Yang-Ming Zhang, Jia Li

ACS Med Chem Lett· June 2014

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Novel small-molecule AMPK activator orally exerts beneficial effects on diabetic db/db mice.
Yuan-Yuan Li, Li-Fang Yu, Li-Na Zhang, Bei-Ying Qiu, Ming-Bo Su

Toxicol Appl Pharmacol· December 2013

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Development of Novel Alkene Oxindole Derivatives As Orally Efficacious AMP-Activated Protein Kinase Activators.
Li-Fang Yu, Yuan-Yuan Li, Ming-Bo Su, Mei Zhang, Wei Zhang

ACS Med Chem Lett· May 2013

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Synthesis and biological evaluation of piperamide analogues as HDAC inhibitors.
Yu Luo, Hao-Min Liu, Ming-Bo Su, Li Sheng, Yu-Bo Zhou

Bioorg Med Chem Lett· August 2011

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Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees.
Astrid Spannhoff, Yong Kee Kim, Noel J-M Raynal, Vazganush Gharibyan, Ming-Bo Su

EMBO Rep· March 2011

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Small molecule antagonizes autoinhibition and activates AMP-activated protein kinase in cells.
Tao Pang, Zhen-Shan Zhang, Min Gu, Bei-Ying Qiu, Li-Fang Yu, Ming-Bo Su

J Biol Chem· June 2008

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