Publications by authors named "Alfred Lewin"

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Modulation of retinal inflammation delays degeneration in a mouse model of geographic atrophy.
Raela B Ridley, Brianna M Tischner, Jieun Lee, Erin Walsh, Michael T Massengill, Alfred S Lewin

Sci Rep· August 2025

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Mitochondrial DNA Damage in the Retinal Pigmented Epithelium (RPE) and Its Role in RPE Pathobiology.
Raela B Ridley, Ashley C Amontree, Alfred S Lewin, Cristhian J Ildefonso

Adv Exp Med Biol· February 2025

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Corneal application of SOCS1/3 peptides for the treatment of eye diseases mediated by inflammation and oxidative stress.
Chulbul M Ahmed, Howard M Johnson, Alfred S Lewin

Front Immunol· August 2024

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Suppressor of cytokine signaling 3-derived peptide as a therapeutic for inflammatory and oxidative stress-induced damage to the retina.
Chulbul M Ahmed, Anil P Patel, Howard M Johnson, Cristhian J Ildefonso, Alfred S Lewin

Mol Vis· January 2024

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Buspirone Enhances Cell Survival and Preserves Structural Integrity during Oxidative Injury to the Retinal Pigment Epithelium.
Manas R Biswal, Ryan J Paulson, Riddhi Vichare, Alfred S Lewin

Antioxidants (Basel)· December 2023

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Inhibition of Ryanodine Receptor 1 Reduces Endoplasmic Reticulum (ER) Stress and Promotes ER Protein Degradation in Cyclic Nucleotide-Gated Channel Deficiency.
Fan Yang, Hongwei Ma, Rekha Garg, Alfred Lewin, Xi-Qin Ding

Adv Exp Med Biol· July 2023

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Binocular benefit following monocular subretinal AAV injection in a mouse model of autosomal dominant retinitis pigmentosa (adRP).
Chulbul M Ahmed, Michael T Massengill, Cristhian J Ildefonso, Archana Jalligampala, Ping Zhu, Alfred S Lewin

Vision Res· May 2023

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Modulation of Retinal Inflammation Delays Degeneration in a Mouse Model of Geographic Atrophy.
Raela B Ridley, Brianna M Bowman, Jieun Lee, Erin Walsh, Michael T Massengill, Alfred S Lewin

bioRxiv· February 2023

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Gene Therapy for Rhodopsin Mutations.
Alfred S Lewin, W Clay Smith

Cold Spring Harb Perspect Med· August 2022

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Individual and Synergistic Anti-Coronavirus Activities of SOCS1/3 Antagonist and Interferon α1 Peptides.
Chulbul M Ahmed, Tristan R Grams, David C Bloom, Howard M Johnson, Alfred S Lewin

Front Immunol· July 2022

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Gene Delivery of a Caspase Activation and Recruitment Domain Improves Retinal Pigment Epithelial Function and Modulates Inflammation in a Mouse Model with Features of Dry Age-Related Macular Degeneration.
Mayur Choudhary, Cristhian J Ildefonso, Alfred S Lewin, Goldis Malek

J Ocul Pharmacol Ther· June 2022

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Gene Therapy for Rhodopsin-associated Autosomal Dominant Retinitis Pigmentosa.
Michael T Massengill, Alfred S Lewin

Int Ophthalmol Clin· October 2021

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Erythropoietin Gene Therapy Delays Retinal Degeneration Resulting from Oxidative Stress in the Retinal Pigment Epithelium.
Manas R Biswal, Zhaoyao Wang, Ryan J Paulson, Rukshana R Uddin, Yao Tong, Alfred S Lewin

Antioxidants (Basel)· May 2021

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Corneal Application of R9-SOCS1-KIR Peptide Alleviates Endotoxin-Induced Uveitis.
Chulbul M Ahmed, Anil P Patel, Cristhian J Ildefonso, Howard M Johnson, Alfred S Lewin

Transl Vis Sci Technol· March 2021

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Automated segmentation and analysis of retinal microglia within ImageJ.
Neil F Ash, Michael T Massengill, Lindsey Harmer, Ahmed Jafri, Alfred S Lewin

Exp Eye Res· February 2021

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SOCS, Intrinsic Virulence Factors, and Treatment of COVID-19.
Howard M Johnson, Alfred S Lewin, Chulbul M Ahmed

Front Immunol· December 2020

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Sectoral activation of glia in an inducible mouse model of autosomal dominant retinitis pigmentosa.
Michael T Massengill, Neil F Ash, Brianna M Young, Cristhian J Ildefonso, Alfred S Lewin

Sci Rep· October 2020

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Preface.
Lung-Ji Chang, Alfred S Lewin

Curr Gene Ther· April 2020

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A C-terminal peptide from type I interferon protects the retina in a mouse model of autoimmune uveitis.
Chulbul M Ahmed, Cristhian J Ildefonso, Howard M Johnson, Alfred S Lewin

PLoS One· April 2020

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AMPK May Play an Important Role in the Retinal Metabolic Ecosystem.
Emily E Brown, Alfred S Lewin, John D Ash

Adv Exp Med Biol· February 2020

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Biodistribution of adeno-associated virus type 2 with mutations in the capsid that contribute to heparan sulfate proteoglycan binding.
Oleg S Gorbatyuk, Kenneth H Warrington, Marina S Gorbatyuk, Irene Zolotukhin, Alfred S Lewin

Virus Res· December 2019

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AAV Mediated Delivery of Myxoma Virus M013 Gene Protects the Retina against Autoimmune Uveitis.
Raela B Ridley, Brianna M Young, Jieun Lee, Erin Walsh, Chulbul M Ahmed, Alfred S Lewin

J Clin Med· November 2019

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SRD005825 Acts as a Pharmacologic Chaperone of Opsin and Promotes Survival of Photoreceptors in an Animal Model of Autosomal Dominant Retinitis Pigmentosa.
Chulbul M Ahmed, Brian T Dwyer, All Romashko, Stev Van Adestine, Eun-He Park, Alfred S Lewin

Transl Vis Sci Technol· November 2019

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Expression of a CARD Slows the Retinal Degeneration of a Geographic Atrophy Mouse Model.
Brianna M Young, Kyle Jones, Michael T Massengill, Erin Walsh, Hong Li, Alfred S Lewin

Mol Ther Methods Clin Dev· September 2019

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Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors.
Emily E Brown, Alexander J DeWeerd, Cristhian J Ildefonso, Alfred S Lewin, John D Ash

Redox Biol· June 2019

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