Publications by authors named "Alfred Merrill"

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The Emerging Mycotoxin 2-Amino-14, 16-Dimethyloctadecan-3-ol (AOD) Alters Transcriptional Regulation and Sphingolipid Metabolism and Undergoes -Acylation by HepG2 Cells.
Shenlong Mo, Zhenying Hu, Huaiyi Zhu, Boming Yu, Xiaoyan Chen, Alfred H Merrill

Toxins (Basel)· August 2025

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The bioactive sphingolipid playbook. A primer for the uninitiated as well as sphingolipidologists.
Yusuf A Hannun, Alfred H Merrill, Chiara Luberto

J Lipid Res· June 2025

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Don't Be Surprised When These Surprise You: Some Infrequently Studied Sphingoid Bases, Metabolites, and Factors That Should Be Kept in Mind During Sphingolipidomic Studies.
Alfred H Merrill

Int J Mol Sci· January 2025

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A Brief Overview of the Toxic Sphingomyelinase Ds of Brown Recluse Spider Venom and Other Organisms and Simple Methods To Detect Production of Its Signature Cyclic Ceramide Phosphate.
Hannah Lachmayr, Alfred H Merrill

Mol Pharmacol· February 2024

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Brain pathology and cerebellar purkinje cell loss in a mouse model of chronic neuronopathic Gaucher disease.
Yael Pewzner-Jung, Tammar Joseph, Shani Blumenreich, Ayelet Vardi, Natalia Santos Ferreira, Alfred H Merrill

Prog Neurobiol· February 2021

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Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures.
Gerhard Liebisch, Eoin Fahy, Junken Aoki, Edward A Dennis, Thierry Durand, Alfred H Merrill

J Lipid Res· December 2020

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The regulation of p53, p38 MAPK, JNK and XBP-1s by sphingosine kinases in human embryonic kidney cells.
Mariam Alsanafi, Samuel L Kelly, Melissa McNaughton, Alfred H Merrill, Nigel J Pyne

Biochim Biophys Acta Mol Cell Biol Lipids· April 2020

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Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin.
Espen Melum, Xiaojun Jiang, Kristi D Baker, M Fatima Macedo, Jürgen Fritsch, Alfred H Merrill

Nat Immunol· December 2019

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Analysis of 1-Deoxysphingoid Bases and Their -Acyl Metabolites and Exploration of Their Occurrence in Some Food Materials.
Junliang Wan, Jian Li, Sibali Bandyopadhyay, Samuel L Kelly, Yang Xiang, Alfred H Merrill

J Agric Food Chem· November 2019

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Ceramide synthase inhibition by fumonisins: a perfect storm of perturbed sphingolipid metabolism, signaling, and disease.
Ronald T Riley, Alfred H Merrill

J Lipid Res· July 2019

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Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice.
Natalia Presa, Robin D Clugston, Susanne Lingrell, Samuel E Kelly, Alfred H Merrill

Biochim Biophys Acta Mol Basis Dis· January 2019

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Native and Polyubiquitinated Forms of Dihydroceramide Desaturase Are Differentially Linked to Human Embryonic Kidney Cell Survival.
Mariam Alsanafi, Samuel L Kelly, Karawan Jubair, Melissa McNaughton, Rothwelle J Tate, Alfred H Merrill

Mol Cell Biol· December 2018

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Eleven residues determine the acyl chain specificity of ceramide synthases.
Rotem Tidhar, Iris D Zelnik, Giora Volpert, Shifra Ben-Dor, Samuel Kelly, Alfred H Merrill

J Biol Chem· June 2018

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Critical Role for Very-Long Chain Sphingolipids in Invariant Natural Killer T Cell Development and Homeostasis.
Ashish Saroha, Yael Pewzner-Jung, Natalia S Ferreira, Piyush Sharma, Youenn Jouan, Alfred H Merrill

Front Immunol· November 2017

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Opinion article on lipidomics: Inherent challenges of lipidomic analysis of sphingolipids.
Alfred H Merrill, M Cameron Sullards

Biochim Biophys Acta Mol Cell Biol Lipids· August 2017

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Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death.
Santosh K Dasari, Shani Bialik, Smadar Levin-Zaidman, Vered Levin-Salomon, Alfred H Merrill

Cell Death Differ· July 2017

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Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein.
Natalia Santos Ferreira, Hanne Engelsby, Ditte Neess, Samuel L Kelly, Giora Volpert, Alfred H Merrill

J Biol Chem· May 2017

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Oxidative stress elicited by modifying the ceramide acyl chain length reduces the rate of clathrin-mediated endocytosis.
Giora Volpert, Shifra Ben-Dor, Ohad Tarcic, Jingjing Duan, Ann Saada, Alfred H Merrill

J Cell Sci· April 2017

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Novel Interconnections in Lipid Metabolism Revealed by Overexpression of Sphingomyelin Synthase-1.
Gergana M Deevska, Patrick P Dotson, Alexander A Karakashian, Giorgis Isaac, Mark Wrona, Alfred H Merrill

J Biol Chem· March 2017

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Identification of Modifier Genes in a Mouse Model of Gaucher Disease.
Andrés D Klein, Natalia-Santos Ferreira, Shifra Ben-Dor, Jingjing Duan, John Hardy, Alfred H Merrill

Cell Rep· September 2016

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Delineating pathological pathways in a chemically induced mouse model of Gaucher disease.
Ayelet Vardi, Hila Zigdon, Anna Meshcheriakova, Andrés D Klein, Chen Yaacobi, Alfred H Merrill

J Pathol· August 2016

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Development of pheochromocytoma in ceramide synthase 2 null mice.
Woo-Jae Park, Ori Brenner, Aviram Kogot-Levin, Ann Saada, Alfred H Merrill

Endocr Relat Cancer· August 2015

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Introduction to Thematic Minireview Series: Novel Bioactive Sphingolipids.
Alfred H Merrill, George M Carman

J Biol Chem· June 2015

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1-Deoxysphingolipids Encountered Exogenously and Made de Novo: Dangerous Mysteries inside an Enigma.
Jingjing Duan, Alfred H Merrill

J Biol Chem· June 2015

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Biomarkers of NAFLD progression: a lipidomics approach to an epidemic.
D Lee Gorden, David S Myers, Pavlina T Ivanova, Eoin Fahy, Mano R Maurya, Alfred H Merrill

J Lipid Res· March 2015

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