Publications by authors named "Alfred T Harding"

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Single-cell analysis of human airway epithelium identifies cell-type-specific responses to and .
Alfred T Harding, Arianne J Crossen, Yanting Zhang, Jennifer L Reedy, Kyle J Basham, Hannah Brown Harding

mBio· November 2025

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Oxidative Stress and Interferon Signaling Drive Differential Pathogenesis of Ancestral and Contemporary Zika Viruses in Human Cerebral Organoids.
Alfred T Harding, Yichen Zhang, Jane-Jane Chen, Jenna M Antonucci, Alexsia Richards

bioRxiv· August 2025

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Human Brain Organoids: A New Model to Study Neurotropism.
Alfred T Harding, Lee Gehrke, Jatin M Vyas, Hannah Brown Harding

J Fungi (Basel)· July 2025

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Single-cell analysis of human airway epithelium identifies cell type-specific responses to and .
Alfred T Harding, Arianne J Crossen, Jennifer L Reedy, Kyle J Basham, Olivia W Hepworth, Hannah Brown Harding

bioRxiv· September 2024

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Human otic progenitor cell models of congenital hearing loss reveal potential pathophysiologic mechanisms of Zika virus and cytomegalovirus infections.
Alfred T Harding, Karen Ocwieja, Minjin Jeong, Yichen Zhang, Valerie Leger

mBio· April 2024

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Mechanisms of Neuroinvasion and Neuropathogenesis by Pathologic Flaviviruses.
Liset de Vries, Alfred T Harding

Viruses· January 2023

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Single-cell genome-wide association reveals that a nonsynonymous variant in confers increased susceptibility to influenza virus.
Benjamin H Schott, Liuyang Wang, Xinyu Zhu, Alfred T Harding, Emily R Ko

Cell Genom· November 2022

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Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.
Tomer M Yaron, Brook E Heaton, Tyler M Levy, Jared L Johnson, Tristan X Jordan, Alfred T Harding

Sci Signal· October 2022

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Rapid tissue prototyping with micro-organospheres.
Zhaohui Wang, Matteo Boretto, Rosemary Millen, Naveen Natesh, Elena S Reckzeh, Alfred T Harding

Stem Cell Reports· September 2022

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A Virion-Based Combination Vaccine Protects against Influenza and SARS-CoV-2 Disease in Mice.
Ryan R Chaparian, Alfred T Harding, Cait E Hamele, Kristina Riebe, Amelia Karlsson

J Virol· August 2022

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The Impact of Estrogens and Their Receptors on Immunity and Inflammation during Infection.
Alfred T Harding, Nicholas S Heaton

Cancers (Basel)· February 2022

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ETV7 limits antiviral gene expression and control of influenza viruses.
Heather M Froggatt, Alfred T Harding, Ryan R Chaparian, Nicholas S Heaton

Sci Signal· July 2021

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GPER1 is required to protect fetal health from maternal inflammation.
Alfred T Harding, Marisa A Goff, Heather M Froggatt, Jean K Lim, Nicholas S Heaton

Science· January 2021

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The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro.
Tomer M Yaron, Brook E Heaton, Tyler M Levy, Jared L Johnson, Tristan X Jordan, Alfred T Harding

bioRxiv· December 2020

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Influenza viruses that require 10 genomic segments as antiviral therapeutics.
Alfred T Harding, Griffin D Haas, Benjamin S Chambers, Nicholas S Heaton

PLoS Pathog· November 2019

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Control of antiviral innate immune response by protein geranylgeranylation.
Shigao Yang, Alfred T Harding, Catherine Sweeney, David Miao, Gregory Swan

Sci Adv· May 2019

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Efforts to Improve the Seasonal Influenza Vaccine.
Alfred T Harding, Nicholas S Heaton

Vaccines (Basel)· March 2018

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A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host Factor.
Brook E Heaton, Edward M Kennedy, Rebekah E Dumm, Alfred T Harding, Matthew T Sacco

Cell Rep· August 2017

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Rationally Designed Influenza Virus Vaccines That Are Antigenically Stable during Growth in Eggs.
Alfred T Harding, Brook E Heaton, Rebekah E Dumm, Nicholas S Heaton

mBio· June 2017

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