Publications by authors named "Alice Long"

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Neutrophil-enriched gene signature correlates with teplizumab therapy resistance in different stages of type 1 diabetes.
Gabriele Sassi, Pierre Lemaitre, Laia Fernández Calvo, Francesca Lodi, Álvaro Cortés Calabuig, S Alice Long

J Clin Invest· December 2025

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Mutant p53 binds RNA to drive mitochondrial dysfunction.
Wuyue Zhou, Alice Long, Cameron J Douglas, Dalila Gallegos, James M Burke

bioRxiv· November 2025

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Transcriptional fingerprinting of regulatory T cells: ensuring quality in cell therapy applications.
Zhang Cheng, Li-Jie Wang, Yuchi Honaker, Steven A Cincotta, Claire E Page, S Alice Long

Front Immunol· July 2025

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Longitudinally stable T cell function and innate immune activation distinguish healthy adult immunotypes.
Megan E Smithmyer, Alex Hu, Matthew J Dufort, Anne M Hocking, Alice E Wiedeman, S Alice Long

Sci Transl Med· June 2025

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Latent EBV enhances the efficacy of anti-CD3 mAb in Type 1 diabetes.
Ana Lledó-Delgado, Paula Preston-Hurlburt, Lauren Higdon, Alex Hu, Eddie James, S Alice Long

Nat Commun· May 2025

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Mesoscale proximity labeling to study macro changes to chromatin occupancy.
Cameron J Douglas, Preston Samowitz, Feifei Tong, Alice Long, Caitlin M Bradley

bioRxiv· March 2025

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Emerging Concepts and Success Stories in Type 1 Diabetes Research: A Road Map for a Bright Future.
Roberto Mallone, Emily Sims, Peter Achenbach, Chantal Mathieu, Alberto Pugliese, S Alice Long

Diabetes· January 2025

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Early expansion of TIGIT+PD1+ effector memory CD4 T cells via agonistic effect of alefacept in new-onset type 1 diabetes.
Lauren E Higdon, Laura A Cooney, Elisavet Serti, Duangchan Suwannasaen, Virginia S Muir, S Alice Long

J Immunol· January 2025

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PD-L1 and PD-1 Are Associated with Clinical Outcomes and Alveolar Immune Cell Activation in Acute Respiratory Distress Syndrome.
Eric D Morrell, Sarah E Holton, Alice Wiedeman, Susanna Kosamo, Mallorie A Mitchem, S Alice Long

Am J Respir Cell Mol Biol· November 2024

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42-parameter mass cytometry panel to assess cellular and functional phenotypes of leukocytes in bronchoalveolar lavage of Rhesus macaque.
Mohau S Makatsa, Anna Kus, Alice Wiedeman, S Alice Long, Chetan Seshadri

bioRxiv· September 2024

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Teplizumab induces persistent changes in the antigen-specific repertoire in individuals at risk for type 1 diabetes.
Ana Lledó-Delgado, Paula Preston-Hurlburt, Sophia Currie, Pamela Clark, Peter S Linsley, S Alice Long

J Clin Invest· August 2024

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Impact on in-depth immunophenotyping of delay to peripheral blood processing.
Lauren E Higdon, Sheila Scheiding, Anna M Kus, Noha Lim, S Alice Long

Clin Exp Immunol· July 2024

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Integrating Omics into Functional Biomarkers of Type 1 Diabetes.
S Alice Long, Peter S Linsley

Cold Spring Harb Perspect Med· July 2024

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Interconnected lineage trajectories link conventional and natural killer (NK)-like exhausted CD8 T cells beneficial in type 1 diabetes.
Erin M Witkop, Kirsten Diggins, Alice Wiedeman, Elisavet Serti, Gerald Nepom, S Alice Long

Commun Biol· June 2024

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A phase 2 randomized trial with autologous polyclonal expanded regulatory T cells in children with new-onset type 1 diabetes.
Christine Bender, Alice E Wiedeman, Alex Hu, Alyssa Ylescupidez, William K Sietsema, S Alice Long

Sci Transl Med· May 2024

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Couple-close construction of polycyclic rings from diradicals.
Alice Long, Christian J Oswood, Christopher B Kelly, Marian C Bryan, David W C MacMillan

Nature· April 2024

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Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review.
Jamie L Felton, Maria J Redondo, Richard A Oram, Cate Speake, S Alice Long

Commun Med (Lond)· April 2024

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A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab.
Chantal Mathieu, Alice Wiedeman, Karen Cerosaletti, S Alice Long, Elisavet Serti

Diabetologia· January 2024

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High proinsulin:C-peptide ratio identifies individuals with stage 2 type 1 diabetes at high risk for progression to clinical diagnosis and responses to teplizumab treatment.
Emily K Sims, Susan M Geyer, S Alice Long, Kevan C Herold

Diabetologia· December 2023

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Th2 cell clonal expansion at diagnosis in human type 1 diabetes.
Aditi Narsale, Francisco Almanza, Theo Tran, Breanna Lam, David Seo, S Alice Long

Clin Immunol· December 2023

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Inhibition of polyamine biosynthesis preserves β cell function in type 1 diabetes.
Emily K Sims, Abhishek Kulkarni, Audrey Hull, Stephanie E Woerner, Susanne Cabrera, S Alice Long

Cell Rep Med· November 2023

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Disease-modifying therapies and features linked to treatment response in type 1 diabetes prevention: a systematic review.
Jamie L Felton, Kurt J Griffin, Richard A Oram, Cate Speake, S Alice Long

Commun Med (Lond)· October 2023

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Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine.
Deirdre K Tobias, Jordi Merino, Abrar Ahmad, Catherine Aiken, Jamie L Benham, S Alice Long

Nat Med· October 2023

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Shifts in isoform usage underlie transcriptional differences in regulatory T cells in type 1 diabetes.
Jeremy R B Newman, S Alice Long, Cate Speake, Carla J Greenbaum, Karen Cerosaletti

Commun Biol· September 2023

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Latent EBV impairs immune cell signaling and enhances the efficacy of anti-CD3 mAb in Type 1 Diabetes.
Ana Lledo Delgado, Paula Preston-Hurlburt, Noha Lim, Tomokazu S Sumida, S Alice Long

medRxiv· July 2023

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