Publications by authors named "Alison Cave"

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Implementation and Results of Active Vaccine Safety Monitoring During the COVID-19 Pandemic in the UK: A Regulatory Perspective.
Jenny Wong, Katherine Donegan, Kendal Harrison, Tahira Jan, Alison Cave

Drug Saf· December 2025

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Recommendations to Enable Broader Use of Real-World Evidence to Inform Decision-Making Throughout Pharmacovigilance Signal Management.
G Niklas Norén, Katherine Donegan, Monica A Muñoz, Thamir M Alshammari, Nicole Pratt, Alison Cave

Pharmacoepidemiol Drug Saf· October 2025

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A Regulatory Perspective on a UK Federated Data Network for Medicines and Medical Devices: Lessons from a 'Study-A-Thon'.
Helen P Booth, John Connelly, Daniel Dedman, Katherine Donegan, Alison Cave

Ther Innov Regul Sci· August 2025

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Time Series Methods to Assess the Impact of Regulatory Action: A Study of UK Primary Care and Hospital Data on the Use of Fluoroquinolones.
Yuchen Guo, Berta Raventós, Martí Català, Leena Elhussein, Kim López-Güell, Alison Cave

Pharmacoepidemiol Drug Saf· October 2024

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The prescription of valproate: risk of harm.
Alison Cave

Lancet Neurol· June 2024

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Choosing drugs for UK COVID-19 treatment trials.
Patrick F Chinnery, Marion Bonnet, Alison Cave, Matthias P Hofer, Alastair Lamb

Nat Rev Drug Discov· February 2022

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Different Strategies to Execute Multi-Database Studies for Medicines Surveillance in Real-World Setting: A Reflection on the European Model.
Rona Gini, Miriam C J Sturkenboom, Janet Sultana, Alison Cave, Annalisa Landi

Clin Pharmacol Ther· August 2020

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Regulatory and health technology assessment advice on postlicensing and postlaunch evidence generation is a foundation for lifecycle data collection for medicines.
Jane Moseley, Spiros Vamvakas, Michael Berntgen, Alison Cave, Xavier Kurz

Br J Clin Pharmacol· June 2020

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Big Data - How to Realize the Promise.
Alison Cave, Nikolai C Brun, Fergus Sweeney, Guido Rasi, Thomas Senderovitz

Clin Pharmacol Ther· April 2020

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Can We Rely on Results From IQVIA Medical Research Data UK Converted to the Observational Medical Outcome Partnership Common Data Model?: A Validation Study Based on Prescribing Codeine in Children.
Gianmario Candore, Karin Hedenmalm, Jim Slattery, Alison Cave, Xavier Kurz

Clin Pharmacol Ther· April 2020

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Real-World Data for Regulatory Decision Making: Challenges and Possible Solutions for Europe.
Alison Cave, Xavier Kurz, Peter Arlett

Clin Pharmacol Ther· July 2019

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Electronic healthcare databases in Europe: descriptive analysis of characteristics and potential for use in medicines regulation.
Alexandra Pacurariu, Kelly Plueschke, Patricia McGettigan, Daniel R Morales, Jim Slattery, Alison Cave

BMJ Open· September 2018

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EU-funded initiatives for real world evidence: descriptive analysis of their characteristics and relevance for regulatory decision-making.
Kelly Plueschke, Patricia McGettigan, Alexandra Pacurariu, Xavier Kurz, Alison Cave

BMJ Open· June 2018

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Endothelial NADPH oxidase-2 promotes interstitial cardiac fibrosis and diastolic dysfunction through proinflammatory effects and endothelial-mesenchymal transition.
Colin E Murdoch, Sanjay Chaubey, Lingfang Zeng, Bin Yu, Aleksander Ivetic, Alison C Cave

J Am Coll Cardiol· June 2014

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Nox2 is required for macrophage chemotaxis towards CSF-1.
Sanjay Chaubey, Gareth E Jones, Ajay M Shah, Alison C Cave, Claire M Wells

PLoS One· July 2013

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Endothelial Nox4 NADPH oxidase enhances vasodilatation and reduces blood pressure in vivo.
Robin Ray, Colin E Murdoch, Minshu Wang, Celio X Santos, Min Zhang, Alison C Cave

Arterioscler Thromb Vasc Biol· June 2011

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The use of long acting β₂-agonists, alone or in combination with inhaled corticosteroids, in chronic obstructive pulmonary disease (COPD): a risk-benefit analysis.
Alison C Cave, Martin M Hurst

Pharmacol Ther· May 2011

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Selective targeting of NADPH oxidase for cardiovascular protection.
Alison Cave

Curr Opin Pharmacol· April 2009

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Protein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia.
Melanie Marshall, Narayana Anilkumar, Joanne Layland, Simon J Walker, Jonathan C Kentish, Alison C Cave

Cardiovasc Res· April 2009

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Involvement of Nox2 NADPH oxidase in adverse cardiac remodeling after myocardial infarction.
Yee H Looi, David J Grieve, Anjana Siva, Simon J Walker, Narayana Anilkumar, Alison C Cave

Hypertension· February 2008

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NADPH oxidases in cardiovascular health and disease.
Alison C Cave, Alison C Brewer, Anilkumar Narayanapanicker, Robin Ray, David J Grieve

Antioxid Redox Signal· March 2007

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NADPH oxidase-dependent redox signalling in cardiac hypertrophy, remodelling and failure.
Colin E Murdoch, Min Zhang, Alison C Cave, Ajay M Shah

Cardiovasc Res· July 2006

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Aldosterone mediates angiotensin II-induced interstitial cardiac fibrosis via a Nox2-containing NADPH oxidase.
Sofian Johar, Alison C Cave, Anilkumar Narayanapanicker, David J Grieve, Ajay M Shah

FASEB J· July 2006

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Glycated proteins stimulate reactive oxygen species production in cardiac myocytes: involvement of Nox2 (gp91phox)-containing NADPH oxidase.
Min Zhang, Ay Lin Kho, Narayana Anilkumar, Rakesh Chibber, Patrick J Pagano, Alison C Cave

Circulation· March 2006

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Involvement of the nicotinamide adenosine dinucleotide phosphate oxidase isoform Nox2 in cardiac contractile dysfunction occurring in response to pressure overload.
David J Grieve, Jonathan A Byrne, Anjana Siva, Joanne Layland, Sofian Johar, Alison C Cave

J Am Coll Cardiol· February 2006

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