Publications by authors named "Alison Humbles"

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Oxidised IL-33 drives COPD epithelial pathogenesis ST2-independent RAGE/EGFR signalling complex.
Sam Strickson, Kirsty F Houslay, Victor A Negri, Yoichiro Ohne, Tomas Ottosson, Alison A Humbles

Eur Respir J· September 2023

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Proteomic profiling of serum identifies a molecular signature that correlates with clinical outcomes in COPD.
Rania Dagher, Paul Fogel, Jingya Wang, David Soussan, Chia-Chien Chiang, Alison A Humbles

PLoS One· December 2022

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Novel mechanisms of action contributing to benralizumab's potent anti-eosinophilic activity.
Rania Dagher, Varsha Kumar, Alan M Copenhaver, Sandra Gallagher, Mahboobe Ghaedi, Alison A Humbles

Eur Respir J· March 2022

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Microbial Regulation of Enteric Eosinophils and Its Impact on Tissue Remodeling and Th2 Immunity.
Rodrigo Jiménez-Saiz, Varun C Anipindi, Heather Galipeau, Yosef Ellenbogen, Roopali Chaudhary, Alison Humbles

Front Immunol· March 2021

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Isolation, Culture, and Induction of Plasticity in ILC2s.
Jonathan Silver, Alison A Humbles, Yoichiro Ohne

Methods Mol Biol· February 2021

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IL-33-ST2 axis regulates myeloid cell differentiation and activation enabling effective club cell regeneration.
Rania Dagher, Alan M Copenhaver, Valerie Besnard, Aaron Berlin, Fatima Hamidi, Alison A Humbles

Nat Commun· September 2020

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Eosinophils, basophils and type 2 immune microenvironments in COPD-affected lung tissue.
Prajakta Jogdand, Premkumar Siddhuraj, Michiko Mori, Caroline Sanden, Jimmie Jönsson, Alison A Humbles

Eur Respir J· May 2020

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Author Correction: c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies.
Jochem H Bernink, Yoichiro Ohne, Marcel B M Teunissen, Jingya Wang, Jincheng Wu, Alison A Humbles

Nat Immunol· January 2020

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c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies.
Jochem H Bernink, Yoichiro Ohne, Marcel B M Teunissen, Jingya Wang, Jincheng Wu, Alison A Humbles

Nat Immunol· August 2019

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Tissue kallikrein regulates alveolar macrophage apoptosis early in influenza virus infection.
Melia Magnen, Fabien Gueugnon, Agnès Petit-Courty, Thomas Baranek, Damien Sizaret, Alison A Humbles

Am J Physiol Lung Cell Mol Physiol· June 2019

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Distal respiratory tract viral infections in young children trigger a marked increase in alveolar mast cells.
Cecilia K Andersson, Medya Shikhagaie, Michiko Mori, Amal Al-Garawi, Jennifer L Reed, Alison A Humbles

ERJ Open Res· October 2018

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Kallikrein-Related Peptidase 5 Contributes to H3N2 Influenza Virus Infection in Human Lungs.
Mélia Magnen, Fabien Gueugnon, Antoine Guillon, Thomas Baranek, Virginie C Thibault, Alison A Humbles

J Virol· August 2017

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NK cells join the plasticity party.
Jonathan S Silver, Alison A Humbles

Nat Immunol· August 2017

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Role of BAFF in pulmonary autoantibody responses induced by chronic cigarette smoke exposure in mice.
Mathieu C Morissette, Yang Gao, Pamela Shen, Danya Thayaparan, Jean-Christophe Bérubé, Alison A Humbles

Physiol Rep· December 2016

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Altered expression of the CCN genes in the lungs of mice in response to cigarette smoke exposure and viral and bacterial infections.
Fabien Gueugnon, Virginie C Thibault, Jennifer Kearley, Agnès Petit-Courty, Amandine Vallet, Alison A Humbles

Gene· July 2016

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Erratum: IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity.
Yoichiro Ohne, Jonathan S Silver, LuAnn Thompson-Snipes, Magalie A Collet, Jean Philippe Blanck, Alison A Humbles

Nat Immunol· July 2016

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Erratum: Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs.
Jonathan S Silver, Jennifer Kearley, Alan M Copenhaver, Caroline Sanden, Michiko Mori, Alison A Humbles

Nat Immunol· July 2016

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IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity.
Yoichiro Ohne, Jonathan S Silver, LuAnn Thompson-Snipes, Magalie A Collet, Jean Philippe Blanck, Alison A Humbles

Nat Immunol· June 2016

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Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs.
Jonathan S Silver, Jennifer Kearley, Alan M Copenhaver, Caroline Sanden, Michiko Mori, Alison A Humbles

Nat Immunol· June 2016

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S100A9 induced inflammatory responses are mediated by distinct damage associated molecular patterns (DAMP) receptors in vitro and in vivo.
Bo Chen, Allison L Miller, Marlon Rebelatto, Yambasu Brewah, Daniel C Rowe, Alison A Humbles

PLoS One· December 2015

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Allergen induced pulmonary inflammation enhances mammary tumor growth and metastasis: Role of CHI3L1.
Stephania Libreros, Ramon Garcia-Areas, Patricia Keating, Nathalia Gazaniga, Philip Robinson, Alison Humbles

J Leukoc Biol· May 2015

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Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin-33-dependent response to infection.
Jennifer Kearley, Jonathan S Silver, Caroline Sanden, Zheng Liu, Aaron A Berlin, Alison A Humbles

Immunity· March 2015

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Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage.
Tara E Sutherland, Nicola Logan, Dominik Rückerl, Alison A Humbles, Stuart M Allan

Nat Immunol· December 2014

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Cigarette smoke primes the pulmonary environment to IL-1α/CXCR-2-dependent nontypeable Haemophilus influenzae-exacerbated neutrophilia in mice.
Jake K Nikota, Pamela Shen, Mathieu C Morissette, Kimberly Fernandes, Abraham Roos, Alison A Humbles

J Immunol· September 2014

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Indigenous enteric eosinophils control DCs to initiate a primary Th2 immune response in vivo.
Derek K Chu, Rodrigo Jimenez-Saiz, Christopher P Verschoor, Tina D Walker, Susanna Goncharova, Alison A Humbles

J Exp Med· July 2014

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